Disease

Hyperglycemia

About the Disease
Hyperglycemia is related to type 1 diabetes mellitus and maturity-onset diabetes of the young, type 2, and has symptoms including cachexia, cyanosis and dyspnea. An important gene associated with Hyperglycemia is MALAT1 (Metastasis Associated Lung Adenocarcinoma Transcript 1), and among its related pathways/superpathways are Metabolism and Nervous system development. The drugs Saxagliptin and Aripiprazole have been mentioned in the context of this disorder. Affiliated tissues include endothelial, liver and brain, and related phenotypes are Decreased viability and Decreased viability

Common Targets
LDLR | SLC5A2 | AVP | ITIH1 | NF-kappaB (NFkB) | MDH2 | gamma-Secretase | PREP | AMP-activated protein kinase (AMPK) | Interleukin 17 (nonspecified subtype) | GPR119 | PRC1 | G7099 | LOC105375494 | ACE | FFAR1 | DPYS | Glycogen phosphorylase (nonspecified subtype) | IL17RA | ADIPOQ | PTGIR | Somatostatin receptor (nonspecified subtype) | PPARA | ESR2 | GH1 | TYR | GCK | CYC1 | UGCG | CDKAL1 | CPT1A | PIK3R1 | SLC22A12 | MC2R | ICAM1 | MIR495 | ABCA1 | SLC6A9 | PPARG | Peroxisome Proliferator-Activated Receptors (PPAR) (nonspecified subtype) | NPY2R | PCSK9 | HSD11B1 | VCAM1 | PTGS1 | PPARD | CPT2 | DPP4 | MTNR1B | G2099 | INSR | G9429 | PYGL | GIPR | ARAP1 | PTPN1 | ACHE | XDH | GCKR | G2309 | G3630 | ZBED3-AS1 | G7124 | Mitogen-Activated Protein Kinase (nonspecified subtype) | JAZF1 | WFS1 | NR1H4 | G367 | ADAMTS9-AS2 | CTLA4 | SST | ABCC8 | G5743 | FGF11 | PKM | FASN | Carnitine O-palmitoyltransferase 2 (nonspecified subtype) | KCNQ1 | Serine protease (nonspecified subtype) | G196 | MTHFR | SPHK1 | TP53INP1 | OASL | SLC5A1 | ASIC1 | GAA | ADRB2 | NOTCH2 | SLC2A9 | Sterol Regulatory Element-Binding Protein (nonspecified subtype) | NR1D1 | CYP19A1 | FTO | IL6R | FABP4 | IDE | alpha-Amylase (nonspecified subtype) | SLC30A8 | ALOX5 | ERP44 | SIRT3 | NNMT | GALR2 | GLP1R | PGK1 | G3569 | HNF1B | TCF7L2 | alpha-Mannosidase (nonspecified subtype) | UCP2 | TRPM3 | THADA | GCGR | KCNJ11

疾病靶点研报
Hyperglycemia

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