Familial Partial Lipodystrophy

About the Disease
Familial Partial Lipodystrophy, also known as lipodystrophy, familial partial, is related to lipodystrophy, familial partial, type 1 and lipodystrophy, familial partial, type 6, and has symptoms including myalgia An important gene associated with Familial Partial Lipodystrophy is LMNA (Lamin A/C), and among its related pathways/superpathways are Metabolism and Signal Transduction. The drugs Chenodeoxycholic acid and Pharmaceutical Solutions have been mentioned in the context of this disorder. Affiliated tissues include skin, liver and pancreas, and related phenotypes are no effect and no effect

Common Targets
ANGPTL3 | PPARG | Peroxisome Proliferator-Activated Receptors (PPAR) (nonspecified subtype) | APOC3 | LEPR | PNPLA2 | LMNA | PLIN1 | LIPE | POLD1

Note: If you'd like to get a target analysis report for Familial Partial Lipodystrophy, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Familial Partial Lipodystrophy at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Glaucoma, Congenital | Heart Septal Defects | Bulimia Nervosa | Plasma Cell Dyscrasia | Cutaneous Mastocytosis | Persistent Truncus Arteriosus | Esophagitis, Eosinophilic | Alcoholism | Cryptosporidiosis | Encephalitis | Meniere's Disease | Adult Polyglucosan Body Disease | Spinocerebellar Ataxia Type 6 | Carcinoma, Squamous Cell | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Endocarditis | Growth Hormone Excess | Shock, Cardiogenic | Androgen Insensitivity | Tylosis With Esophageal Cancer | Meningococcal Meningitis | Congenital Absence Of Vas Deferens | NGLY1 Deficiency | Glycogen Storage Disease Type 1a | Pure Autonomic Failure | Diverticulitis | Anencephaly | Polycystic Kidney, Autosomal Recessive | Encephalocele | Ghosal Syndrome | Neurofibromatosis | Chronic Beryllium Disease | Epidermal Nevus Syndrome | Autoimmune Polyendocrinopathy Syndrome Type I | Renpenning Syndrome | Systemic Mastocytosis | Pulmonary Alveolar Microlithiasis | Xeroderma Pigmentosum Variant Type | Ganglioneuroma | Nephrosclerosis | Alopecia Totalis | Thyroid Dysgenesis | Periventricular Nodular Heterotopia | Multiple Sulfatase Deficiency | Encephalopathy, Hepatic | Proteasome-associated Autoinflammatory Syndrome 2 | VACTERL/VATER Association | Hypoplastic Left Heart Syndrome | Encephalopathy, Ethylmalonic | Mandibuloacral Dysplasia With Type A Lipodystrophy | Osteoarthritis | Ocular Albinism Type 1 | Odonto-onycho-dermal Dysplasia | Protein C Deficiency | Salla Disease | Urolithiasis | Pearson Syndrome | Crimean-Congo Hemorrhagic Fever | Empyema | Spermatocele | Thymoma, Malignant | Thrombosis | Hyperuricemia | Muir-Torre Syndrome | Sepiapterin Reductase Deficiency | Contact Dermatitis | Wolfram Syndrome | Bicuspid Aortic Valve | Syndactyly | Acne Vulgaris | Long QT Syndrome Type 3 | Lafora Disease | Gaucher Disease | L-2-Hydroxyglutaric Aciduria | X-linked Myotubular Myopathy | Vitamin B12 Deficiency | Prurigo Nodularis | Enhanced S-cone Syndrome | Basal Ganglia Cerebrovascular Disease | Infantile Refsum Disease | Epilepsy | Spinocerebellar Ataxia Type 40 | Cryoglobulinemia | Cyclic Vomiting Syndrome | Thyroiditis | Aplastic Anemia | Periventricular Leukomalacia | Paronychia | Hemolytic Uremic Syndrome | Arthrogryposis | Eiken Syndrome | Colitis, Microscopic | Gigantism | C3 Glomerulonephritis | Donnai-Barrow Syndrome | Pilomatrix Carcinoma | Hyperparathyroidism, Primary | Camptocormia | Atrial Septal Defect | Tumoral Calcinosis | Multiple Hamartoma Syndrome | Carcinoma, Merkel Cell | Lymphoma | Osteochondrosis | Blomstrand Osteochondrodysplasia | Progressive External Ophthalmoplegia | Central Pain Syndrome | Spina Bifida | Androgenic Alopecia | Spinocerebellar Ataxia Type 16 | Optic Neuritis | Mumps | Intestinal Obstruction | Huntington's Disease-like 2 | Coffin-Lowry Syndrome | Neonatal Progeroid Syndrome | Hereditary Folate Malabsorption | Hypogammaglobulinemia | Cancer, Breast | Lennox-Gastaut Syndrome | Familial Hypobetalipoproteinemia | Dystonia Musculorum Deformans | Malaria | Charcot-Marie-Tooth Disease Type 4D | 3-methylglutaconic Aciduria | Malonyl-CoA Decarboxylase Deficiency | Hamartoma | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Congenital Dyserythropoietic Anemia | Coma | Neurocutaneous Syndromes | Situs Inversus | Hyperparathyroidism, Secondary | Arthritis | Cancer, Colon | Marfan Syndrome | Meningioma | Tularemia | Osteomalacia | Pheochromocytoma | H Syndrome | Malaria, Cerebral | Sjogren Syndrome | Demyelinating Diseases | Corneal Dystrophies, Hereditary | Tuberculous Meningitis | Leukoplakia, Oral | Ventricular Septal Defect | Familial Exudative Vitreoretinopathy | 3C Syndrome | Chronic Inflammatory Demyelinating Polyneuropathy | Chronic Mucocutaneous Candidiasis | Hernia, Inguinal | Smith-Lemli-Opitz Syndrome | Creatine Deficiency Syndrome | Adenoid Cystic Carcinoma | Long QT Syndrome Type 2 | Polyarteritis Nodosa | Acrodermatitis | Uveitis | Cardiomyopathy, Hypertrophic | Fibromuscular Dysplasia | Maternally Inherited Diabetes And Deafness | Japanese Encephalitis | Asphyxia Neonatorum | Hypogonadism | Polycythemia | Asplenia | Glycogen Storage Disease Type 5 | Sickle Cell Disease | Cardiomyopathy, Dilated, 1L | Sclerosteosis | Craniometaphyseal Dysplasia | Dengue Shock Syndrome | Muscle Wasting | Lymphangioleiomyomatosis | Pulmonary Vein Stenosis | Pineoblastoma | Diabetic Macular Edema | Sialidosis Type I | Evans Syndrome | Diabetes Type 2 | Meningioma, Benign | Spinocerebellar Ataxia Type 17 | Borjeson-Forssman-Lehmann Syndrome | Prolidase Deficiency | Congenital Muscular Dystrophy | Intracerebral Hemorrhage | Chronic Neutrophilic Leukemia | Sleep Apnea, Obstructive | Cancer, Kidney | Cat Eye Syndrome | Ovarian Sex Cord-stromal Tumor | Cancer, Lung | Charcot-Marie-Tooth Disease, Type 6 | Hypertension, Renovascular | Aneurysm, Thoracic Aortic | Spinocerebellar Ataxia Type 20 | Sclerocornea | Fibrosis | Iron Metabolism Disorders | Waldenstrom Macroglobulinemia | Hepatoblastoma | Schwartz-Jampel-Aberfeld Syndrome | Mevalonate Kinase Deficiency | Spinocerebellar Ataxia Type 2 | Beta-Propeller Protein-associated Neurodegeneration | Pulmonary Stenosis | Dubin-Johnson Syndrome | Subcortical Band Heterotopia | Pneumonia, Bacterial | Allan-Herndon-Dudley Syndrome | Osteochondroma | Hypermetropia | Patent Foramen Ovale | Transcobalamin Deficiency | Schwannoma | Hypodontia | Acromicric Dysplasia | Primary Familial Brain Calcification | Neurocutaneous Melanocytosis | Spinocerebellar Ataxia Type 27 | Snyder-Robinson Syndrome | Colitis, Collagenous | Acute Coronary Syndrome | Cataplexy | Aphasia | Nephroblastoma | Raine Syndrome | Wieacker-Wolff Syndrome | Delirium | DEND Syndrome | Hemochromatosis | Pulmonary Veno-occlusive Disease | Erythromelalgia | Babesiosis | Teratozoospermia | Lung Diseases | Primary Cutaneous Amyloidosis | Dysequilibrium Syndrome | Glutaric Aciduria Type 2 | Duodenal Atresia | Metachondromatosis | Restless Legs Syndrome | Sarcoma, Endometrial Stromal | Acute Motor Axonal Neuropathy | Trigonocephaly | Fontaine Progeroid Syndrome | Persistent Fetal Circulation | Scleritis | Centronuclear Myopathy | Imerslund-Grasbeck Syndrome | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Idiopathic Pulmonary Fibrosis | Vici Syndrome | Autoimmune Autonomic Ganglionopathy | Holt-Oram Syndrome | Sezary Syndrome | Osteogenesis Imperfecta Type III | Multiple System Atrophy | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Eccrine Porocarcinoma | Cerebellar Ataxia, Cayman Type | Erythema Multiforme | Agammaglobulinemia | Congenital Central Hypoventilation Syndrome | Burn-McKeown Syndrome | Goiter | Pontocerebellar Hypoplasia Type 7 | Porphyria Cutanea Tarda | Congenital Dysfibrinogenemia | Waardenburg Syndrome Type 2A | Adrenal Insufficiency | Myofibrillar Myopathy | Lassa Fever | Osteoporosis | Prune Belly Syndrome | Deafness, Dystonia, And Cerebral Hypomyelination | Myelomeningocele | Acquired Partial Lipodystrophy | Neuromyelitis Optica | Microphthalmia, Syndromic 7 | Hypotrichosis | Sickle Cell Anemia | Exfoliative Dermatitis | Rhinitis | Schizotypal Personality Disorder | T-cell Prolymphocytic Leukemia | Keratopathy | Congenital Nystagmus | Adenomyosis | Glutaric Aciduria Type 1 | Glioblastoma | Sitosterolemia | Inflammatory Bowel Disease | Menkes Disease | Adenosine Deaminase 2 Deficiency | Familial Hyperaldosteronism | Arthropathy | Uremic Pruritus | Schistosomiasis Mansoni | Cirrhosis | Stickler Syndrome | Renal Oncocytoma | Atrioventricular Septal Defect | Chudley-McCullough Syndrome | Hepatitis D | Macular Degeneration | Bardet-Biedl Syndrome | Nestor-Guillermo Progeria Syndrome | Familial Thoracic Aortic Aneurysm | MIRAGE Syndrome | Intracranial Hypertension | Paracoccidioidomycosis | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Neutrophilia | Gastroenteritis, Eosinophilic | Infantile Liver Failure Syndrome 1 | Cleidocranial Dysplasia | Paget's Disease Of The Breast | High Molecular Weight Kininogen Deficiency | Chromosome 5q Deletion Syndrome | Carbohydrate Metabolism Disorders | Eating Disorder | Hypertension, Portal | Scleroderma | Nephrotic Syndrome | Congenital Tufting Enteropathy | Leri Pleonosteosis | Polymyalgia Rheumatica | Torticollis | Superficial Spreading Melanoma | Diabetes Mellitus, Transient Neonatal | Erythrokeratodermia Variabilis | Silicosis | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Pyruvate Kinase Deficiency | Greenberg Dysplasia | Sick Sinus Syndrome | Cannabis Abuse | Infantile Nephropathic Cystinosis | Retinal Diseases | Actinomycetoma | Granular Corneal Dystrophy | Retinal Coloboma | Low Tension Glaucoma | Wilson's Disease | Aspergillosis | Malnutrition | Lattice Corneal Dystrophy Type 1 | Sporadic Inclusion Body Myositis | Pathological Gambling | Ocular Hypertension | Large Granular Lymphocytic Leukemia | Wiskott-Aldrich Syndrome | Currarino Syndrome | Epidermolysis Bullosa | Oligoastrocytoma | Panniculitis | Ovarian Hyperstimulation Syndrome | Conn Syndrome | Asthma, Nocturnal | Apert Syndrome | Sleep Disorder | Cardiac Arrest | Zollinger-Ellison Syndrome | Sarcoidosis, Pulmonary | Neurofibroma, Plexiform | Histiocytic Sarcoma | Twin-to-twin Transfusion Syndrome | Carpenter Syndrome | Bronchiolitis | Tendinitis | Hypohidrotic Ectodermal Dysplasia | Glycogen Storage Disease Type 0, Muscle | Peyronie's Disease | Uveitis, Anterior | Succinic Semialdehyde Dehydrogenase Deficiency | Epilepsy, Generalized | Bietti Crystalline Dystrophy | Chorea-acanthocytosis | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Chondrodysplasia Punctata 2, X-linked Dominant | Congenital Poikiloderma | Non-Hodgkin Lymphoma | Bacterial Meningitis | Gastritis, Atrophic | Hyperferritinemia-cataract Syndrome | Gilbert Syndrome | Epidermodysplasia Verruciformis | Acute Lung Injury | Progressive Osseous Heteroplasia | Arteriosclerosis | Myoclonus | Congenital Dyserythropoietic Anemia Type 4 | Encephalitis, Tick-borne | Leukocyte Adhesion Deficiency | Neuromuscular Disorders | McKusick Type Metaphyseal Chondrodysplasia