Lung Diseases

About the Disease
Lung Disease, also known as lung diseases, is related to interstitial lung disease and interstitial lung disease 2, and has symptoms including apnea, coughing and dyspnea. An important gene associated with Lung Disease is SFTPC (Surfactant Protein C), and among its related pathways/superpathways are Metabolism of proteins and Innate Immune System. The drugs Guaifenesin and Cathine have been mentioned in the context of this disorder. Affiliated tissues include lung, bone marrow and heart, and related phenotypes are homeostasis/metabolism and immune system

Common Targets
ELANE | HLA-B | SGCD | HLA-DRB1 | PDE4B | NBPF6 | MLKL | G4780 | ADAMTS7 | IL2RA | GABRA4 | G59272 | Ribosomal Protein S6 Kinase, 90kDa (nonspecified subtype) | ALOX5AP | EPHX2 | C5 | LPAR1 | FOXF1 | BRD4 | G598 | LCK | MMP3 | VOR Complex | LAMB1 | NKX2-1 | TRPV1 | MAP3K5 | KEAP1 | SSH2 | CYP1A1 | LOX | MMP12 | ADORA2B | DYRK1A | MAP3K8 | ARG1 | DPP4 | SLC9A3 | PTK6 | SMPD1 | PDZRN4 | ADORA2A | GSTT1 | CELF4 | PGAM5-KEAP1-NRF2 Complex | ADCY2 | INSR | MASP2 | G4318 | FLNA | SFTPC | GSK3B | IRAK4 | NR1H4 | Epithelial Sodium Channel (ENaC) | TBX4 | CYP2F1 | MUC5B | G1956 | K(ATP) Channel (nonspecified subtype) | NOS3 | SMAD9 | JAG1 | KDR | CXCR3 | Glycogen synthase kinase 3 (GSK-3) (nonspecified subtype) | ACVRL1 | CSNK1A1 | MMP2 | GPR84 | PDE5A | CCL1 | HPRT1 | Transforming growth factor beta (nonspecified subtype) | IL1B | SFTPD | NMDA receptor | ROCK2 | TPH1 | ERBB4 | G3569 | LYN | CFTR | GSTP1 | VHL | NAMPT | IRF6 | NLRP3 Inflammasome | AGER | SLC6A14 | NOTCH2 | EGLN1 | FYN | CRBN | G114548 | HLA-C | KRR1 | Arginase (nonspecified subtype) | Angiotensin receptor (AT) (nonspecified subtype) | NQO1 | G596 | RIPK1 | GSPT1 | ABCA3 | MMP1 | EGLN2 | CLK2 | G6714 | TGFB1 | ARG2 | HDAC6 | DNA Methyltransferase (DNMT) (nonspecified subtype) | TIMP3 | SELE | YES1 | CAT | HCK | CGAS | G7124 | EGLN3 | FGR | GPR35

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