Disease

Craniosynostosis

About the Disease
Craniosynostosis, also known as premature closure of cranial sutures, is related to muenke syndrome and jackson-weiss syndrome. An important gene associated with Craniosynostosis is FGFR2 (Fibroblast Growth Factor Receptor 2), and among its related pathways/superpathways are Breast cancer pathway and Endochondral ossification. The drugs Tranexamic acid and Hemostatics have been mentioned in the context of this disorder. Affiliated tissues include Bone, and related phenotypes are no effect and no effect

Common Targets
SIX2 | IDUA | COLEC11 | COLEC10 | CDC45 | G4851 | GLI2 | F13A1 | ADAMTSL4 | AHDC1 | FGFR1 | SHC4 | WDR83 | TCF12 | POR | BMP7 | MSX2 | G3845 | GLI3 | G3480 | ERF | ASXL3 | CNOT7 | FRY | SMAD6 | DLG1 | CLYBL | ADCK1 | KAT6A | VPS37A | FLNA | CENPP | LINC00955 | RAF1 | PRRX1 | SCARF2 | FREM1 | JAG1 | FGF9 | TIE1 | FASN | NF-kappaB (NFkB) | NF1 | SH3PXD2B | LINC01387 | IL11RA | TFAP2B | G673 | ATOH7 | KMT2D | MEGF8 | HUWE1 | BCL11B | PTPN11 | BMPER | KAT6B | AXIN2 | NOTCH2 | ZIC1 | CYP26B1 | TMCO1 | PIN1 | CNTNAP2 | NOG | WDR35 | RAB23 | LRRC15 | IFT122 | MASP1 | SP7 | G6774 | AHNAK2 | FGFR2 | KIR3DL3 | NELL1 | TGFBR2 | ATR | HOXC4 | TWIST1 | COG1 | SPECC1L | SPATA31E1 | NTRK2 | ETF1 | SOX11 | GNPTAB | NRBF2 | FUZ | SIX1 | EFNA4 | SMO | EFNB1 | FAM20C | DGKH | FGFR3 | ALX4 | TOP1 | RUNX2 | ALPL | RECQL4 | SKI | BBS9 | FBN1

疾病靶点研报
Craniosynostosis

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