Primary Hyperparathyroidism
Primary Hyperparathyroidism
About the Disease
Primary Hyperparathyroidism, also known as familial primary hyperparathyroidism, is related to hyperparathyroidism 2 with jaw tumors and hyperparathyroidism 1. An important gene associated with Primary Hyperparathyroidism is MEN1 (Menin 1), and among its related pathways/superpathways are Signal Transduction and G alpha (s) signalling events. The drugs Salmon calcitonin and Strontium ranelate have been mentioned in the context of this disorder. Affiliated tissues include bone, kidney and thyroid, and related phenotypes are no effect and no effect
Common Targets
HRAS | CDC73 | CASR | PTK2B | MEN1 | PTH1R | GCM2
Note: If you'd like to get a target analysis report for Primary Hyperparathyroidism, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Primary Hyperparathyroidism at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.
Other Diseases
Malaria | Dermatomyositis | Varicocele | Amelogenesis Imperfecta | Bronchitis, Chronic | Erythematotelangiectatic Rosacea | Tuberculous Meningitis | Benign Familial Pemphigus | Thyroid Dysgenesis | Kallmann Syndrome | Liver Diseases | Pancreatitis, Chronic | Dermatofibrosarcoma | Pyruvate Carboxylase Deficiency Disease | Optic Nerve Diseases | Low Tension Glaucoma | Glutaric Aciduria Type 1 | Familial Partial Lipodystrophy | Dermatitis | Autoimmune Hemolytic Anemia | Long QT Syndrome Type 3 | Biotinidase Deficiency | Poikiloderma With Neutropenia | Sleep Disorder | Micropenis | Norrie Disease | Non-epidermolytic Palmoplantar Keratoderma | Fuchs Dystrophy | Megalencephaly | Teratozoospermia | Neuroectodermal Tumors, Primitive | Cluster Headache | Acute Lymphocytic Leukemia | Polycythemia Vera | Pulmonary Alveolar Microlithiasis | Crouzon Syndrome With Acanthosis Nigricans | Hyperparathyroidism, Primary | Meesmann Corneal Dystrophy | Apparent Mineralocorticoid Excess Syndrome | Epidermolysis Bullosa | Scleroderma | Polycystic Kidney, Autosomal Recessive | Cystitis, Interstitial | DOCK8 Immunodeficiency Syndrome | Autoimmune Disease | Temporal Lobe Epilepsy | Rhizomelic Chondrodysplasia Punctata | Lyme Disease | Dysthymia | Jaundice, Obstructive | Congenital Lipoid Adrenal Hyperplasia | Exocrine Pancreatic Insufficiency | Saul-Wilson Syndrome | Neurofibromatosis Type 1 | Pyruvate Kinase Deficiency | Spinal Muscular Atrophy Type 2 | Nanophthalmos | Hepatitis E | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Alpers Syndrome | Metachromatic Leukodystrophy | Mountain Sickness | Microcephaly, Seizures, And Developmental Delay | Geleophysic Dysplasia | Schizophrenia | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Cancer, Skin | Thyroid Dyshormonogenesis | Sickle Cell Anemia | Transcobalamin Deficiency | Non-Langerhans Cell Histiocytosis | Onchocerciasis | Hemochromatosis Type 1 | Progressive Myoclonic Epilepsy | Cartilage Disorders | Rift Valley Fever | Familial Cerebral Amyloid Angiopathy | Cone Dystrophy | Mitochondrial Disease | Idiopathic Pulmonary Fibrosis | Vascular Cognitive Impairment | Pituitary Dwarfism | Pontocerebellar Hypoplasia Type 2 | Neovascular Glaucoma | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Congenital Hypofibrinogenemia | CEDNIK Syndrome | Isovaleric Acidemia | Renal Hypouricemia | Coenzyme Q10 Deficiency | Erythropoietic Protoporphyria | Hypertension, Pulmonary | Esophagitis | Mitochondrial DNA Depletion Syndrome 13 | Osteoglophonic Dysplasia | Histiocytosis | SAPHO Syndrome | Congenital Stromal Corneal Dystrophy | Neurocysticercosis | Antithrombin III Deficiency | Cholesteryl Ester Storage Disease | Kearns-Sayre Syndrome | Benign Familial Neonatal Convulsions | Arthrogryposis | Campomelic Dysplasia | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Fragile X Syndrome | Cirrhosis | Mannosidase Deficiency Diseases | Hypermetropia | HANAC Syndrome | Chondrodysplasia Punctata 1, X-linked Recessive | Acquired Partial Lipodystrophy | Leiomyoma | Spondyloperipheral Dysplasia | Polydactyly | Cryptosporidiosis | Chylothorax, Congenital | Acral Lentiginous Melanoma | Arthritis, Psoriatic | Mucolipidosis Type III | Hypertriglyceridemia | Otopalatodigital Syndrome Type 2 | Glioblastoma | Autonomic Neuropathy | Lipoma | Crohn's Disease | Myofibrillar Myopathy | Hypokalemic Periodic Paralysis | Tyrosine Hydroxylase Deficiency | Thrombophilia | Kabuki Syndrome | Alopecia | Acute Anterior Uveitis | NDH Syndrome | Bone Giant Cell Tumor | Klinefelter Syndrome | Depression | Vitamin D Deficiency | Dentinogenesis Imperfecta | ADNP Syndrome | Charcot-Marie-Tooth Disease Type 4 | Early Infantile Epileptic Encephalopathy 4 | Adrenomyeloneuropathy | Sclerosteosis 2 | Fetal And Neonatal Alloimmune Thrombocytopenia | Hypotrichosis Simplex | Oral Lichen Planus | Yellow Fever | Inflammatory Myofibroblastic Tumor | Brachydactyly | Diffuse Palmoplantar Keratoderma | Medulloblastoma | Epithelioid Hemangioma | Skin Carcinoma | Dubin-Johnson Syndrome | Borjeson-Forssman-Lehmann Syndrome | Hyperprolactinemia | Ollier Disease | Wolcott-Rallison Syndrome | Leukemia | Pantothenate Kinase-associated Neurodegeneration | Antley-Bixler Syndrome | Christianson Syndrome | Creatine Deficiency Syndrome Due To AGAT Deficiency | Hypereosinophilic Syndrome | Spinocerebellar Ataxia Type 12 | Lysosomal Acid Lipase Deficiency | Pigment Dispersion Syndrome | Keratosis | Spina Bifida | Becker Muscular Dystrophy | Maternally Inherited Diabetes And Deafness | Carney-Stratakis Syndrome | Gastroenteritis, Eosinophilic | Ichthyosis, X-linked | Rheumatoid Arthritis | Costello Syndrome | Pierson Syndrome | Myeloid Leukemia | Postpartum Depression | Poirier-Bienvenu Neurodevelopmental Syndrome | Raine Syndrome | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Autoimmune Autonomic Ganglionopathy | Intestinal Hypomagnesemia 1 | Esotropia | Short-chain Acyl-CoA Dehydrogenase Deficiency | Perivascular Epithelioid Cell Tumor | Malnutrition | Congenital Dyserythropoietic Anemia Type 4 | Gastritis, Atrophic | Viral Meningitis | Van Der Knaap Disease | Desmosterolosis | Vascular Calcification | Histoplasmosis | Usher Syndrome Type II | Pontocerebellar Hypoplasia | CDKL5 Deficiency Disorder | Acute Chest Syndrome | Dyslexia | Osteopathia Striata With Cranial Sclerosis | Schwartz-Jampel-Aberfeld Syndrome | Perry Syndrome | Heart Failure | Waardenburg Syndrome | Distal Spinal Muscular Atrophy | Miyoshi Myopathy | Pycnodysostosis | Thrombophlebitis | Gliosarcoma | Insulin Resistance | Craniosynostosis | Chorea | C3 Glomerulopathy | Heimler Syndrome | Charcot-Marie-Tooth Disease, Type 2 | Mycosis Fungoides | Myositis, Focal | Keratopathy | Spinocerebellar Ataxia Type 8 | Mumps | Open-angle Glaucoma | Joubert Syndrome 2 | Spondylometaphyseal Dysplasia | Constipation | Parkinson Disease 6, Autosomal Recessive Early-onset | Pseudo-pseudohypoparathyroidism | Cutaneous Mastocytosis | Astigmatism | Macular Corneal Dystrophy Type 1 | Osteogenesis Imperfecta Type VI | Basal Ganglia Cerebrovascular Disease | Cancer, Bladder | Vitamin B12 Deficiency | Nephropathy | Corneal Neovascularization | Fibrosarcoma | Usher Syndrome Type III | Cleidocranial Dysplasia | Neural Tube Defect | Sarcomatoid Carcinoma Of The Lung | Ehlers-Danlos Syndrome | Lymphoma, B-cell | Erysipelas | Joubert Syndrome | 5-oxoprolinase Deficiency | Usher Syndrome Type I | Lymphoma Lymphoblastic | Cerebrotendinous Xanthomatosis | Chromosome 16p11.2 Deletion Syndrome | Spinal And Bulbar Muscular Atrophy | Alkaptonuria | Blastomycosis | Congenital Adrenal Hyperplasia 1 | Pemphigoid | Keratoacanthoma | Myelitis, Transverse | Blepharitis | Common Variable Immunodeficiency | Birt-Hogg-Dube Syndrome | Arthropathy | Waardenburg Syndrome Type 2E | Pain | Purpura, Thrombotic Thrombocytopenic | Frontotemporal Dementia | Optic Neuropathy, Anterior Ischemic | Azoospermia | Palmoplantar Keratoderma | Spinocerebellar Ataxia | Gnathodiaphyseal Dysplasia | Duane Retraction Syndrome | Hypogammaglobulinemia | Hypothyroidism | Pyloric Stenosis, Infantile Hypertrophic | Recurrent Respiratory Papillomatosis | COACH Syndrome | Lentigo | Uveitis | Sotos Syndrome | Nicotine Addiction | Aneurysm, Abdominal Aortic | Methylmalonic Aciduria And Homocystinuria, CblC Type | Pancreatitis | Central Core Disease | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Microphthalmia | Spinocerebellar Ataxia Type 2 | Renpenning Syndrome | Sporadic Hemiplegic Migraine | Cousin Syndrome | T-cell Lymphoma, Subcutaneous Panniculitis-like | Delirium | Preaxial Polydactyly | Patent Foramen Ovale | Phosphoglycerate Dehydrogenase Deficiency | Genee-Wiedemann Syndrome | Gigantism | Primary Sclerosing Cholangitis | Cholangitis | Congenital Central Hypoventilation Syndrome | Diarrhea | Cystitis | IgA Deficiency | Budd-Chiari Syndrome | IgA Nephropathy | Hepatic Steatosis | Gangliosidosis | Premenstrual Syndrome | Colitis, Collagenous | Glycogen Storage Disease Type 3 | Tendinopathy | Jacobsen Syndrome | Werner's Syndrome | Epilepsy Of Infancy With Migrating Focal Seizures | Chronic Myeloid Leukemia | Charcot-Marie-Tooth Disease, Type 2A | Panniculitis | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Cantu Syndrome | Osteomyelitis | Facioscapulohumeral Muscular Dystrophy Type 1 | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Warsaw Breakage Syndrome | Agoraphobia | Choroiditis | TARP Syndrome | Ligneous Conjunctivitis | Pseudohermaphroditism | Impulse Control Disorder | Hyperthermia, Malignant | Endometrial Hyperplasia | Trachoma | Diabetes Insipidus, Neurogenic | Chiari Malformation Type I | Nail Disorder, Nonsyndromic Congenital | Asthma, Nocturnal | Glanzmann Thrombasthenia | Irritable Bowel Syndrome | Diastrophic Dysplasia | Multiple System Atrophy | Bartter Syndrome | Prolymphocytic Leukemia | Kawasaki Disease | Interstitial Lung Diseases | Porphyria, Variegate | Cranioectodermal Dysplasia | Ocular Albinism Type 1 | Hemochromatosis Type 2 | Hydrolethalus Syndrome | Arterial Tortuosity Syndrome | FG Syndrome | Ocular Surface Squamous Neoplasia | Malaria, Cerebral | Atrioventricular Septal Defect | Adenocarcinoma | Fetal Alcohol Syndrome | Ovarian Sex Cord-stromal Tumor | Charcot-Marie-Tooth Disease Type 4B1 | Krabbe Disease | Cardiac Arrest | Empyema | Multiple Sclerosis, Primary Progressive | Congenital Ichthyosiform Erythroderma | Potocki-Shaffer Syndrome | Hemangioblastoma | Imerslund-Grasbeck Syndrome | Primrose Syndrome | Schizotypal Personality Disorder | Trichotillomania | Bernard-Soulier Syndrome | VEXAS Syndrome | Lymphopenia | Waardenburg Syndrome Type 4 | Sarcoma | Retinitis Pigmentosa | Venous Insufficiency | Menkes Disease | Liver Failure, Acute Infantile | MIRAGE Syndrome | Non-proliferative Diabetic Retinopathy | Bacterial Meningitis | Alpha-1 Antitrypsin Deficiency | Glaucomatocyclitic Crisis | Esophageal Adenocarcinoma | Hypoproteinemia, Hypercatabolic | Hypohidrotic Ectodermal Dysplasia | Infantile Neuroaxonal Dystrophy | Binge Eating Disorder | Farber Disease | Hemolytic Anemia | Oculocutaneous Albinism Type 2 | Blomstrand Osteochondrodysplasia | Cardiofaciocutaneous Syndrome | Uveitis, Anterior | Thyroid Hormone Resistance | Ebstein Anomaly | Glycogen Storage Disease Type 1b | Choriocarcinoma