Familial Mediterranean Fever

About the Disease
Familial Mediterranean Fever, also known as periodic fever syndrome, is related to autoinflammation, panniculitis, and dermatosis syndrome and brucellosis, and has symptoms including abdominal pain, arthralgia and fever. An important gene associated with Familial Mediterranean Fever is MEFV (MEFV Innate Immunity Regulator, Pyrin), and among its related pathways/superpathways are Innate Immune System and Disease. The drugs Interleukin 1 Receptor Antagonist Protein and Pharmaceutical Solutions have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, b cells and kidney, and related phenotypes are nausea and vomiting and constipation

Common Targets
Interleukin-1 (nonspecified subtype) | IL1B | FAM161A | IL-1 Receptor (nonspecified subtype) | MVK | G114548 | ABCG5 | NLRP3 Inflammasome | ZNF200 | PTPN22 | CXCR2 | MEFV | IL6R | HLA-DRB1 | TNFRSF1A | IL1RN | SAA1 | HLA-B | G5243 | Tubulin | CYP2D6 | MMP3

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