Onchocerciasis

About the Disease
Onchocerciasis, also known as infection by onchocerca volvulus, is related to loiasis and filariasis. An important gene associated with Onchocerciasis is IL5 (Interleukin 5), and among its related pathways/superpathways are Signal Transduction and MIF Mediated Glucocorticoid Regulation. The drugs Anticonvulsants and Moxidectin have been mentioned in the context of this disorder. Affiliated tissues include skin, eye and t cells, and related phenotypes are immune system and hematopoietic system

Common Targets
Tubulin | MAP3K14 | CDK6 | CDK4

Note: If you'd like to get a target analysis report for Onchocerciasis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Onchocerciasis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Hyperinsulinemia | Blepharo-cheilo-odontic Syndrome | Dementia | Cholecystitis | Low Tension Glaucoma | Gyrate Atrophy Of The Choroid And Retina | Delirium | Arthritis | Molybdenum Cofactor Deficiency | Lassa Fever | Hyperthyroidism | Familial Episodic Pain Syndrome | Sclerocornea | Glycogen Storage Disease Type 4 | Congenital Hereditary Endothelial Dystrophy Type II | Cancer, Colon | Congenital Bilateral Absence Of Vas Deferens | Prader-Willi Syndrome | Arteriosclerosis | Distal Myopathy | Patent Foramen Ovale | Myoclonic Atonic Epilepsy | Postaxial Polydactyly | Niemann-Pick Disease, Type C | Shock, Cardiogenic | Hypertension, Pulmonary | Rheumatoid Arthritis | Hyperbilirubinemia, Neonatal | Multiple Epiphyseal Dysplasia | Necrotizing Autoimmune Myopathy | Richter's Syndrome | Blepharoconjunctivitis | Mabry Syndrome | Transcobalamin Deficiency | Trimethylaminuria | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Gitelman Syndrome | Hartsfield Syndrome | Chondrodysplasia Punctata 2, X-linked Dominant | Thyroid Dyshormonogenesis | Rhabdomyosarcoma | Dentinogenesis Imperfecta | Ectopia Lentis, Isolated, Autosomal Recessive | Ebstein Anomaly | Sleep Apnea, Obstructive | Heart Block | Familial Male-limited Precocious Puberty | Wolfram Syndrome | Hyperostosis | Vitreoretinal Degeneration, Snowflake Type | Malaria, Cerebral | Heterotopic Ossification | Creatine Deficiency Syndrome Due To AGAT Deficiency | Iron Deficiency Anemia | Sarcoidosis, Pulmonary | Progressive Encephalopathy-optic Atrophy Syndrome | Familial Hyperaldosteronism | Porphyria | Hypercholesterolemia, Familial | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Hemoglobinopathies | Lymphoproliferative Disorders | Chondrodysplasia Punctata | Intracranial Hypertension | X-linked Myotubular Myopathy | Intestinal Obstruction | Ichthyosis, X-linked | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Choriocarcinoma | Geleophysic Dysplasia | Carcinoid Syndrome | Metanephric Adenoma | Keratosis, Seborrheic | Conjunctivitis, Allergic | Chitayat Syndrome | Keratosis | Pancreatitis, Chronic | Alzheimer Disease, Late Onset | Encephalopathy | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Costello Syndrome | Pemphigus | Hoyeraal-Hreidarsson Syndrome | Multiple Sulfatase Deficiency | Kaposi Sarcoma | Vitiligo | Duodenal Atresia | Stargardt Disease | Erdheim-Chester Disease | Dysplastic Nevus | Primary Hyperoxaluria | Blomstrand Osteochondrodysplasia | Congenital Bile Acid Synthesis Defect | Fascioliasis | Multiple Sclerosis, Chronic Progressive | Endophthalmitis | Ventricular Septal Defect | Gnathodiaphyseal Dysplasia | Hairy Cell Leukemia | Weill-Marchesani Syndrome | Heart Failure | Lymphedema | Familial Partial Lipodystrophy | Keratosis, Actinic | Pyoderma Gangrenosum | Mosaic Variegated Aneuploidy Syndrome 2 | Combined Deficiency Of Factor V And Factor VIII | Cutaneous Lupus Erythematosus | Diabetic Nephropathy | Chorea | Blue Rubber Bleb Nevus Syndrome | Dowling-Degos Disease | Mastitis | Congenital Dyserythropoietic Anemia | Episodic Ataxia | Diabetic Macular Edema | Charcot-Marie-Tooth Disease | Autoimmune Disease | Mohr-Tranebjaerg Syndrome | Pheochromocytoma | Still Disease | Insulinoma | Carpal Tunnel Syndrome | Epidermolysis Bullosa Simplex | Meier-Gorlin Syndrome | Sleep Apnea | Hypermethioninemia | Chanarin-Dorfman Syndrome | Brooke-Spiegler Syndrome | Cardiomyopathy, Restrictive | Congenital Torticollis | Diffuse Palmoplantar Keratoderma | Thalassemia | Tendinitis | Congestive Heart Failure | Miyoshi Myopathy | Triphalangeal Thumb-polysyndactyly Syndrome | Coloboma | Venous Insufficiency | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Fraser Syndrome | Ganglioneuroma | POEMS Syndrome | KBG Syndrome | Papilloma | Zygomycosis | Ulcerative Colitis | Epicondylitis | Spinocerebellar Ataxia Type 28 | Erythromelalgia | Spinocerebellar Ataxia Type 8 | Lymphangiomatosis | Familial Retinal Arterial Macroaneurysm | Progressive Myoclonic Epilepsy | Hyperkeratosis | Nail-Patella Syndrome | Congenital Mirror Movements | Myelitis, Transverse | Spinal Cord Diseases | Behcet's Disease | Dysthymia | Colitis | Hereditary Sensory Neuropathy Type 1 | Heterotaxy | Eccrine Porocarcinoma | Plasma Cell Leukemia | Pseudohypoparathyroidism Type 1A | Hypophosphatasia | Aplasia Cutis Congenita | Limb Girdle Muscular Dystrophy | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Hyperthermia, Malignant | Intermittent Claudication | Spinocerebellar Ataxia Type 14 | Hemochromatosis | Parapsoriasis | Familial Isolated Hyperparathyroidism | Argininosuccinic Aciduria | Nanophthalmos | Gerstmann-Straussler-Scheinker Syndrome | Narcolepsy | Hyperparathyroidism, Primary | Hereditary Inclusion Body Myopathy | Lennox-Gastaut Syndrome | Cutaneous T-cell Lymphoma | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Chronic Idiopathic Myelofibrosis | Headache | Thrombotic Microangiopathy | Werner's Syndrome | Neuronal Ceroid Lipofuscinosis | Apparent Mineralocorticoid Excess Syndrome | Leukoencephalopathy, Progressive Multifocal | Hyperlipidemia Type V | Epidermolysis Bullosa | Progressive Familial Intrahepatic Cholestasis Type 2 | Borjeson-Forssman-Lehmann Syndrome | Succinic Semialdehyde Dehydrogenase Deficiency | Platelet Disorders | Warsaw Breakage Syndrome | Autoimmune Autonomic Ganglionopathy | Phenylketonuria II | Primary Familial Brain Calcification | Hereditary Folate Malabsorption | Neurofibroma | Basal Ganglia Cerebrovascular Disease | Toxic Epidermal Necrolysis | Melnick-Needles Syndrome | Birt-Hogg-Dube Syndrome | Cleidocranial Dysplasia | Autosomal Recessive Bestrophinopathy | Lafora Disease | Acrodysostosis | Keratopathy | Thrombophlebitis | Corneal Neovascularization | Nevus | Gangliosidosis | Pancreatitis | Precocious Puberty | Synovitis | Hyperhomocysteinemia | Williams Syndrome | Hepatopulmonary Syndrome | Mast Cell Leukemia | Congenital Aniridia | Antithrombin III Deficiency | Spastic Paraplegia Type 7 | Schizophrenia | Inborn Errors Of Metabolism | Gray Platelet Syndrome | Macrodactyly | Hemangioma | Leukocyte Adhesion Deficiency Type 1 | Leishmaniasis, Visceral | Progressive Familial Intrahepatic Cholestasis | Guillain-Barre Syndrome | Arts Syndrome | Dental Caries | Pelvic Inflammatory Disease | Osteomyelitis | Osteoporosis | Huntington's Disease-like 2 | Familial Hemiplegic Migraine | Posterior Polar Cataract | Congenital Heart Block | Colitis, Collagenous | Calcium Pyrophosphate Deposition Disease | Obesity | Greig Cephalopolysyndactyly Syndrome | Noonan Syndrome | Wolfram Syndrome 2 | Meleda Disease | Myopia | Carcinoma, Squamous Cell | Lentigo | Hypoglycemia | Alopecia Totalis | Yellow Fever | Polycythemia | Goiter, Nodular | Cancer, Prostate | Cantu Syndrome | Scleritis | Hypotrichosis Simplex | Loeys-Dietz Syndrome Type 4 | Sweet Syndrome | Paraplegia | Choroiditis | Atopic Dermatitis | Leigh Syndrome | Astrocytoma | Cardiomyopathy, Dilated, 1L | Nestor-Guillermo Progeria Syndrome | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Heavy Chain Disease | Episodic Ataxia Type 2 | Chorea-acanthocytosis | Cysticercosis | Sitosterolemia | Hypersomnia | Oguchi Disease-2 | Pantothenate Kinase-associated Neurodegeneration | Bethlem Myopathy | Pachyonychia Congenita | 3-M Syndrome | Hypertrophy | Hypertriglyceridemia | IMAGe Syndrome | Nephroblastoma | Congenital Central Hypoventilation Syndrome | Non-Hodgkin Lymphoma | Martsolf Syndrome | Barrett Esophagus | Cancer, Bladder | Scapuloperoneal Spinal Muscular Atrophy | Sengers Syndrome | Alexander Disease | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | LMNA-related Congenital Muscular Dystrophy | Eosinophilia | Fetal Alcohol Syndrome | Tyrosinemia | Sporadic Hemiplegic Migraine | Becker Muscular Dystrophy | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Neonatal Progeroid Syndrome | Carney Triad | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Alopecia | Giant Axonal Neuropathy | Rhabdomyosarcoma, Embryonal | Otosclerosis | Knobloch Syndrome | Blepharophimosis Syndrome | Early Infantile Epileptic Encephalopathy 28 | Diamond-Blackfan Anemia | Alazami Syndrome | Encephalitis | Sialidosis Type I | Multifocal Motor Neuropathy | Pure Red Cell Aplasia | Hypocalcemia | Hydrolethalus Syndrome | Lipid Storage Diseases | Benign Familial Pemphigus | B-cell Prolymphocytic Leukemia | Common Variable Immunodeficiency | Spinocerebellar Ataxia Type 31 | Persistent Hyperplastic Primary Vitreous | C3 Glomerulopathy | Sorsby Fundus Dystrophy | SAPHO Syndrome | Galactosialidosis | Primary Carnitine Deficiency | Hydrops Fetalis | Neurocutaneous Syndromes | Adenoma, Pleomorphic | Osteosarcoma | Dengue Hemorrhagic Fever | Granular Corneal Dystrophy Type 1 | Juvenile Xanthogranuloma | Charcot-Marie-Tooth Disease, Type 2C | Alpha-thalassemia Myelodysplasia Syndrome | Multisystemic Smooth Muscle Dysfunction Syndrome | Peeling Skin Syndrome Type B | Colon Adenoma | Occipital Neuralgia | Aspergillosis | Sarcoidosis | Lung Diseases | Retinal Dystrophy | Osteogenesis Imperfecta Type IV | Tyrosine Hydroxylase Deficiency | Lymphopenia | Smith-Magenis Syndrome | Scleroderma, Diffuse | Non-bullous Congenital Ichthyosiform Erythroderma | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | LRBA Deficiency | Hydrocephalus, Normal Pressure | Polyradiculopathy | Autonomic Neuropathy | Camptocormia | Amyloidosis | Inflammatory Myofibroblastic Tumor | Blau Syndrome | Alpers Syndrome | Dyggve-Melchior-Clausen Disease | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Focal Segmental Glomerulosclerosis | Hypertelorism | Sarcomatoid Carcinoma Of The Lung | Membranous Nephropathy | Primary Hyperoxaluria Type 1 | Prurigo Nodularis | Erysipelas | Congenital Adrenal Hyperplasia 1 | Bronchitis | Pneumonia, Mycoplasma | Danon Disease | Arthropathy | X-linked Sideroblastic Anemia | Congenital Afibrinogenemia | Adrenoleukodystrophy, X-linked | 3-methylglutaconic Aciduria Type IV | Subcortical Band Heterotopia | Hypertensive Nephropathy | Cutis Laxa | Deafness, Dystonia, And Cerebral Hypomyelination | Traboulsi Syndrome | Ichthyosis Hystrix, Curth-Macklin Type | Mitochondrial DNA Depletion Syndrome 13 | Shprintzen-Goldberg Syndrome | Wolcott-Rallison Syndrome | Raine Syndrome | Blue Nevus | Neurogenic Bladder | Fibrosarcoma | Microcephaly, Seizures, And Developmental Delay