Disease

Narcolepsy

About the Disease
Narcolepsy, also known as narcoleptic syndrome, is related to narcolepsy 1 and cerebellar ataxia, deafness, and narcolepsy, autosomal dominant, and has symptoms including hemiplegia, sleep disturbances and snoring. An important gene associated with Narcolepsy is HCRT (Hypocretin Neuropeptide Precursor), and among its related pathways/superpathways are Transcription factor regulation in adipogenesis and Orexin receptor pathway. The drugs Central Nervous System Stimulants and Sodium citrate have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and eye.

Common Targets
HNMT | G7124 | PER2 | CCR3 | Glutamate Receptor Ionotropic AMPA Receptor | G5243 | HLA-C | SCN5A | HRH3 | HLA-DQB1 | HCRT | SNORD105 | PPAN | Phosphodiesterase 1 (PDE1) (nonspecified subtype) | Gamma-Aminobutyric acid type B receptor | NPSR1 | PDE1C | Alpha-2 Adrenergic receptors (nonspecified subtype) | CHKB-DT | Calcium channel (nonspecified subtype) | HLA-DQA1 | HCRTR1 | CPT1B | NFATC2 | EIF3G | P2RY11 | HTR2B | SLC6A2 | HLA-B | CACNA1C | SCP2 | DRD2 | Nicotinic alpha4beta2 receptor | GABA(A) receptor | CTSH | HLA-DRB1 | ADRA2A | OPRL1 | HLA-DPA1 | CHKB | ADORA2A | CHKB-CPT1B | PTGDR | HCRTR2 | ADRB1 | ACHE | DRD1 | GSK3B | HLA-A | TRIB2 | PDE1B | CCR1 | HTR1B | alpha1-Adrenoceptor (nonspecified subtype) | SLC6A4 | HLA-DPB1 | NMDA receptor | APP | G1786 | HTR2C | MCHR1 | PDE1A | CHRNB2 | TAAR1 | SLC6A3

疾病靶点研报
Narcolepsy

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