Stevens-Johnson Syndrome

About the Disease
Erythema Multiforme, also known as erythema polymorphe, erythema multiforme type, is related to severe cutaneous adverse reaction and graft-versus-host disease. An important gene associated with Erythema Multiforme is DSP (Desmoplakin), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Calcipotriol and Betamethasone have been mentioned in the context of this disorder. Affiliated tissues include skin, eye and salivary gland, and related phenotypes are no effect and no effect

Common Targets
HLA-DQA1 | TRAF3IP2-AS1 | G5243 | PTGER3 | CFD | IL4R | HLA-A | TMCC3 | DDX39B | LOC105370891 | GSTT1 | REC114 | IL10 | CYP3A5 | IFNG | G7124 | PSORS1C1 | SCN1A | GSTM1 | Complement Complex | CYP2C9 | IL4 | HLA-DPB1 | HLA-DQB1 | Serine-aspartate repeat-containing protein I-like | HLA-C | CYP2B6 | IL13 | EPHX1 | ABCC10 | TRAF3IP2 | ACTG1P25 | HLA-DRB1 | CYP3A4 | HLA-B | TLR3 | CYP2C19 | IGSF11 | BAG6

Note: If you'd like to get a target analysis report for Stevens-Johnson Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Stevens-Johnson Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Gout | Osteogenesis Imperfecta Type V | Patent Ductus Arteriosus | Tietze Syndrome | Restrictive Dermopathy | Transcobalamin Deficiency | ACTH-independent Macronodular Adrenal Hyperplasia | Osteogenesis Imperfecta Type VI | Ocular Albinism Type 1 | Episodic Ataxia Type 2 | Glucagonoma | Multiple Sclerosis, Chronic Progressive | Leri-Weill Dyschondrosteosis | 3-methylglutaconic Aciduria Type I | Glaucomatocyclitic Crisis | Hypokalemia | Intracerebral Hemorrhage | Cramp Fasciculation Syndrome | Abetalipoproteinemia | Retinal Degeneration | Dysfibrinogenemia | Infantile Neuroaxonal Dystrophy | Cranial Nerve Disease | 3-M Syndrome | Enterocolitis, Necrotizing | DICER1 Syndrome | Chromosome 17q21.31 Deletion Syndrome | Hereditary Sensory And Autonomic Neuropathy | Micro Syndrome | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Autoimmune Disease | Osteogenesis Imperfecta Type III | Communication Disorders | Malaria, Cerebral | Scleroderma, Diffuse | Angiodysplasia | Basal Cell Nevus Syndrome | Oligoastrocytoma | Mucormycosis | Neurotoxicity | Medulloblastoma | Gerodermia Osteodysplastica | Erythropoietic Protoporphyria | Chondrodysplasia Punctata | Still Disease | Aceruloplasminemia | Carcinoma, Transitional Cell | Left Ventricular Noncompaction | Costello Syndrome | Hamartoma | Nasodigitoacoustic Syndrome | Macular Corneal Dystrophy Type 1 | Crohn's Disease | Bainbridge-Ropers Syndrome | Gastritis | Epidermolytic Ichthyosis, Annular | Dermatomyositis | Polyneuropathy | Familial Partial Lipodystrophy | Corneal Edema | Ventricular Septal Defect | Hypoproteinemia, Hypercatabolic | Adenoma, Villous | Familial Hyperaldosteronism | Osteoporosis | Tyrosinemia Type 2 | Panic Disorder | Hypotonia-cystinuria Syndrome | Cole-Carpenter Syndrome | Melnick-Needles Syndrome | Pilomatrix Carcinoma | Shock, Cardiogenic | Erythromelalgia | Anuria | Saethre-Chotzen Syndrome | Spinocerebellar Ataxia Type 42 | Ocular Hypertension | Carbamoyl Phosphate Synthetase I Deficiency | Nemaline Myopathy | Pericarditis | Spina Bifida | Endometrial Hyperplasia | Biotinidase Deficiency | Nephrosclerosis | Seminoma | Meesmann Corneal Dystrophy | Cholelithiasis | Intestinal Hypomagnesemia 1 | Blue Nevus | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Dermatitis Herpetiformis | Milk Allergy | Epilepsy Of Infancy With Migrating Focal Seizures | Lipodystrophy | Glomerulonephritis | Scleritis | Anodontia | Enhanced S-cone Syndrome | Hepatitis B, Chronic | Choroiditis | Wolfram Syndrome | Hyperparathyroidism, Secondary | Familial Hypobetalipoproteinemia | Carcinoid Syndrome | Paroxysmal Kinesigenic Dyskinesia | Cat Eye Syndrome | Camurati-Engelmann Disease | Clouston Hidrotic Ectodermal Dysplasia | Depression | Neurofibrosarcoma | Tularemia | Familial Exudative Vitreoretinopathy | Best Macular Dystrophy | Dermatitis | Birk-Barel Syndrome | Asplenia | Wolcott-Rallison Syndrome | Asthma, Nocturnal | Alagille Syndrome | GM2-gangliosidosis AB Variant | Tremor | Posterior Polar Cataract | Influenza | Rubinstein-Taybi Syndrome | Ophthalmia, Sympathetic | Campomelic Dysplasia | Alazami Syndrome | Familial Episodic Pain Syndrome | Oligospermia | Chromosome 8q21.11 Deletion Syndrome | Hyperinsulinemia | Sarcomatoid Carcinoma Of The Lung | Prurigo Nodularis | Tyrosinemia | Neutrophilia | Marfan Syndrome | Diarrhea | Sleep Apnea | Leri Pleonosteosis | Stuve-Wiedemann Syndrome | Neurofibromatosis Type 2 | Retinopathy Of Prematurity | Benign Recurrent Intrahepatic Cholestasis 1 | Adenoma, Pituitary | Neurofibroma | Sarcoma, Alveolar Soft Part | Androgenic Alopecia | Astigmatism | CEDNIK Syndrome | Mucolipidosis | Cellulitis | Early Infantile Epileptic Encephalopathy 4 | Christianson Syndrome | Spondylometaphyseal Dysplasia | Neurofibromatosis | Pleural Tuberculosis | Glomerulonephritis, Membranoproliferative | Walker-Warburg Syndrome | Branchiootorenal Syndrome | Osteomyelitis | Myasthenia | Vulvovaginitis | Aneurysm, Thoracic Aortic | Meleda Disease | Congenital Diaphragmatic Hernia | Atelosteogenesis Type 1 | Rash | Diabetic Macular Edema | Martsolf Syndrome | Diabetes Insipidus, Neurogenic | Schizoaffective Disorder | Pyruvate Decarboxylase Deficiency | Robinow Syndrome | Chronic Beryllium Disease | Spitzoid Melanoma | Carpal Tunnel Syndrome | Oligoasthenoteratozoospermia | Bloom Syndrome | Renal Medullary Carcinoma | Teratozoospermia | Neuroblastoma | Graft-versus-host Disease | Spondyloepiphyseal Dysplasia Tarda, X-linked | Intestinal Tuberculosis | Neural Tube Defect | Osteoarthritis | Craniopharyngioma | Insulin Resistance | H Syndrome | Congenital Generalized Lipodystrophy | Hypersensitivity Pneumonitis | Thrombophilia | Vici Syndrome | Diabetes Type 2 | Congenital Myasthenic Syndrome | Nephrotic Syndrome Type 1 | Schizencephaly | Hepatitis, Alcoholic | Stomatitis | Thyrotoxic Periodic Paralysis | Urticaria | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Combined Deficiency Of Factor V And Factor VIII | Epidermolysis Bullosa Simplex, Localized | Noonan Syndrome | Fascioliasis | Preaxial Polydactyly | Otitis Media | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | DEND Syndrome | Sialidosis Type I | Salla Disease | Agranulocytosis | Multiple Sclerosis, Primary Progressive | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | IgA Nephropathy | Hyperglycemia | KBG Syndrome | Lyme Disease | Diabetes Type 1 | Periventricular Nodular Heterotopia | Epilepsy | Congenital Mirror Movements | Hemimegalencephaly | Chronic Myelomonocytic Leukemia | Ependymoma | Sick Sinus Syndrome 1 | Neurodermatitis | Trichomegaly | Hartnup Disease | Progressive Myoclonic Epilepsy | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Autoimmune Polyendocrine Syndrome | Cystitis, Interstitial | Myocardial Infarction | Hemochromatosis Type 2 | Chorioretinitis | Chronic Lymphocytic Leukemia | Pseudomyxoma Peritonei | Cholera | Liddle Syndrome | Amebiasis | Cohen Syndrome | Tricho-hepato-enteric Syndrome | Homocystinuria | Mitochondrial Cytopathy | Benign Familial Infantile Seizures | Gardner Syndrome | Chorea | Hereditary Xerocytosis | Neurocutaneous Melanocytosis | Aldosterone Deficiency | Bladder Exstrophy | Alpha-1 Antitrypsin Deficiency | Blepharoconjunctivitis | Arthritis | Spitz Nevus | Intestinal Pseudo-obstruction | Takayasu's Arteritis | Spinocerebellar Ataxia Type 38 | Allan-Herndon-Dudley Syndrome | Takotsubo Cardiomyopathy | Hyperlipidemia, Familial Combined | Long QT Syndrome Type 1 | Acrodermatitis Enteropathica | Gerstmann-Straussler-Scheinker Syndrome | Oculocutaneous Albinism Type 1 | Nicolaides-Baraitser Syndrome | Pineoblastoma | Amelanotic Melanoma | Myotonic Disorders | Methemoglobinemia Type IV | Plasmacytoma | Metabolic Diseases | Mucolipidosis Type II | Huntington's Disease | Thrombocytopenia | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Colitis, Microscopic | Situs Inversus | Hyperparathyroidism | Asperger Syndrome | Fahr Disease | Leukocyte Adhesion Deficiency Type 1 | Haim-Munk Syndrome | Esotropia | Blastomycosis | Constipation | Perry Syndrome | Progressive Encephalopathy-optic Atrophy Syndrome | Duodenal Atresia | Progressive External Ophthalmoplegia | Wieacker-Wolff Syndrome | Conjunctivitis | Myeloid Leukemia | Duchenne Muscular Dystrophy | Endophthalmitis | Craniofrontonasal Syndrome | Tuberculous Meningitis | Facioscapulohumeral Muscular Dystrophy | Perivascular Epithelioid Cell Tumor | Anemia | Spinocerebellar Ataxia Type 6 | Microphthalmia | Hemorrhage | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Hypercalciuria | Mabry Syndrome | Neurofibromatosis-Noonan Syndrome | Hypersensitivity | Blepharo-cheilo-odontic Syndrome | Lymphangioleiomyomatosis | Persistent Hyperplastic Primary Vitreous | Donnai-Barrow Syndrome | Fibromyalgia | Retinal Diseases | Charcot-Marie-Tooth Disease Type 4B1 | Diabetes Gestational | Hyperuricemic Nephropathy, Familial Juvenile | Juvenile Polyposis | Palsy, Cerebral | 5-oxoprolinase Deficiency | Atherosclerosis | Paternal Uniparental Disomy Of Chromosome 14 | Thrombocythemia, Essential | Pneumonia, Mycoplasma | Congenital Dyserythropoietic Anemia Type 4 | Vertigo | Microcephaly, Seizures, And Developmental Delay | Hyperprolactinemia | Smith-Kingsmore Syndrome | Hypoalbuminemia | Immunoproliferative Disorders | Eccrine Porocarcinoma | 3-methylglutaconic Aciduria Type IV | Acromesomelic Dysplasia | IgA Deficiency | Venous Insufficiency | Encephalopathy, Hepatic | Glutaric Aciduria Type 3 | Paraplegia | Johanson-Blizzard Syndrome | Localized Scleroderma | Spinocerebellar Ataxia Type 12 | Autism | Familial Dysautonomia | Myelitis, Transverse | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Hyperbilirubinemia | GAPO Syndrome | Sarcosinemia | Acquired Partial Lipodystrophy | Hashimoto Thyroiditis | Barakat Syndrome | Tendinopathy | Neurocutaneous Syndromes | Polycystic Ovary Syndrome | Shprintzen-Goldberg Syndrome | Pseudohypoparathyroidism Type 2 | Basal Ganglia Cerebrovascular Disease | Arthropathy | Goiter | Pityriasis Rubra Pilaris | Prediabetes | Pemphigoid | Achromatopsia | Pancreatitis | Gitelman Syndrome | Urea Cycle Disorder | Sandhoff Disease | Stiff-man Syndrome | Wolman Disease | Citrullinemia | 3-hydroxy-3-methylglutaric Aciduria | Sclerosing Cholangitis | Acanthosis Nigricans | Stroke | Blood Protein Disorders | Pituitary Stalk Interruption Syndrome | Pontocerebellar Hypoplasia Type 2 | Mucolipidosis Type IV | Large Granular Lymphocytic Leukemia | Renal Dysplasia | Epithelioid Hemangioma | Colorectal Adenoma | Cardiomyopathy, Restrictive | Sepiapterin Reductase Deficiency | Lymphomatoid Granulomatosis | Williams Syndrome | Schizophrenia, Paranoid | Inflammatory Bowel Disease | Rhinitis | Aspartylglycosaminuria | Temtamy Preaxial Brachydactyly Syndrome | Farber Disease | Basal Ganglia Disease | Benign Familial Neonatal Convulsions | Diamond-Blackfan Anemia | Blue Rubber Bleb Nevus Syndrome | Juvenile Myelomonocytic Leukemia