5-oxoprolinase Deficiency

About the Disease
Glutathione Synthetase Deficiency, also known as pyroglutamic aciduria, is related to hemolytic anemia and bilirubin metabolic disorder, and has symptoms including abdominal pain, diarrhea and vomiting. An important gene associated with Glutathione Synthetase Deficiency is GSS (Glutathione Synthetase), and among its related pathways/superpathways are Metabolism and Metapathway biotransformation Phase I and II. Affiliated tissues include brain, neutrophil and bone marrow, and related phenotypes are hemolytic anemia and abnormality of immune system physiology

Common Targets
OPLAH

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