Polymyositis

About the Disease
Polymyositis, also known as pm - [polymyositis], is related to inclusion body myositis and interstitial lung disease. An important gene associated with Polymyositis is RN7SL1 (RNA Component Of Signal Recognition Particle 7SL1), and among its related pathways/superpathways are miRNAs involved in DNA damage response and miRNAs involvement in the immune response in sepsis. The drugs Prednisone and Prednisolone phosphate have been mentioned in the context of this disorder. Affiliated tissues include skeletal muscle, heart and bone, and related phenotypes are autoimmunity and emg abnormality

Common Targets
Interferon-alpha (IFN-alpha) (nonspecified subtype) | HOXD4 | ERBB3 | IFNA13 | GLIS3 | PSMB9 | G7015 | MC2R | CD86 | TLR9 | MS4A1 | Interleukin-12 (IL-12) | CTSG | STAT4 | LILRA4 | TNFAIP3 | BLK | MIR146A | PRTN3 | WT1 | IRF5 | HOXB1 | CD80 | Immunoproteasome | S1PR5 | IL12A | IFIH1 | GLP1R | IFNAR1 | TLR7 | S1PR1 | HLA-DRB1 | PSMB8 | ELANE | HLA-B | IFNAR2 | IL12B | TLR8 | Interleukin 23 complex (IL-23) | HOXC11 | TYK2 | EMX2 | ALX4 | HOXD3

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