Filariasis

About the Disease
Filarial Elephantiasis, also known as lymphatic filariasis, is related to loiasis and onchocerciasis, and has symptoms including chyluria An important gene associated with Filarial Elephantiasis is IL10 (Interleukin 10), and among its related pathways/superpathways are Akt Signaling and Overview of interferons-mediated signaling pathway. The drugs Doxycycline and Petrolatum have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and testis, and related phenotypes are lymphadenopathy and predominantly lower limb lymphedema

Common Targets
HLA-DQB1-AS1 | Importin alpha/beta-1 | DNA Methyltransferase (DNMT) (nonspecified subtype) | HLA-DQB1 | HLA-DQA1 | Matrix Metalloproteinase (MMP) (nonspecified subtype) | Chloride channel (nonspecified subtype) | Na+/K+-ATPase (nonspecified subtype) | SLC11A1 | Tubulin | HTR2C

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