Disease

DICER1 Syndrome

About the Disease
Dicer1 Syndrome, also known as dicer1-related pleuropulmonary blastoma cancer predisposition syndrome, is related to pleuropulmonary blastoma and blastoma. An important gene associated with Dicer1 Syndrome is DICER1 (Dicer 1, Ribonuclease III), and among its related pathways/superpathways is Fragile X syndrome. The drugs Cyclophosphamide and Dactinomycin have been mentioned in the context of this disorder. Affiliated tissues include thyroid, lung and liver, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Common Targets
DICER1

疾病靶点研报
DICER1 Syndrome

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