DICER1 Syndrome
DICER1 Syndrome
About the Disease
Dicer1 Syndrome, also known as dicer1-related pleuropulmonary blastoma cancer predisposition syndrome, is related to pleuropulmonary blastoma and blastoma. An important gene associated with Dicer1 Syndrome is DICER1 (Dicer 1, Ribonuclease III), and among its related pathways/superpathways is Fragile X syndrome. The drugs Cyclophosphamide and Dactinomycin have been mentioned in the context of this disorder. Affiliated tissues include thyroid, lung and liver, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)
Common Targets
DICER1

Note: If you'd like to get a target analysis report for DICER1 Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of DICER1 Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.
Other Diseases
Uterine Leiomyoma | Neurofibromatosis Type 2 | Anorchia | Primary Progressive Nonfluent Aphasia | Prader-Willi Syndrome | Encephalitis, Tick-borne | Trigonocephaly | Camurati-Engelmann Disease | Neurodegeneration With Brain Iron Accumulation | Synovitis | Hereditary Inclusion Body Myopathy | Hypertension, Renal | Hypertension, Essential | Hemochromatosis | Vogt-Koyanagi-Harada Syndrome | Melanoma, Malignant | Arthritis, Gouty | Irritable Bowel Syndrome | Spondylo-ocular Syndrome | Dengue Hemorrhagic Fever | Chondrodysplasia Punctata | Inborn Errors Of Metabolism | Pseudohypoparathyroidism Type 1C | Farber Disease | Fragile X Syndrome | Agammaglobulinemia | Hypercalcemia | Neurofibroma, Plexiform | Basal Ganglia Cerebrovascular Disease | Diabetic Nephropathy | Hepatorenal Syndrome | Aneurysm, Abdominal Aortic | Rhabdomyosarcoma, Embryonal | Creatine Deficiency Syndrome | Conduct Disorder | Lupus Erythematosus | Pseudoexfoliation Syndrome | Veno-occlusive Disease | B-cell Prolymphocytic Leukemia | Dystonia | Cerebral Amyloid Angiopathy | Myositis, Focal | Localized Scleroderma | High Molecular Weight Kininogen Deficiency | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Osteogenesis Imperfecta Type III | Congenital Generalized Lipodystrophy | Hereditary Neuropathy With Liability To Pressure Palsies | Pituitary Stalk Interruption Syndrome | Desbuquois Syndrome | Systemic Mastocytosis | Pycnodysostosis | Gerstmann-Straussler-Scheinker Syndrome | Bruck Syndrome | Axenfeld-Rieger Syndrome | Meningeal Melanocytoma | Low Phospholipid Associated Cholelithiasis | Hypogonadism | Dysplastic Nevus | Thanatophoric Dysplasia Type 1 | GM2-gangliosidosis AB Variant | Cockayne Syndrome | McLeod Syndrome | Bone Marrow Necrosis | Cohen Syndrome | Adenomyosis | Connective Tissue Disorders | Waardenburg Syndrome | Alpers Syndrome | Craniofacial Dysostosis | Combined Pituitary Hormone Deficiency | Moyamoya Disease | Ornithine Transcarbamylase Deficiency | Chronic Lymphocytic Leukemia | Crohn's Disease | Craniometaphyseal Dysplasia | Bronchitis | Chondroma | Superficial Spreading Melanoma | Argininosuccinic Aciduria | Liver Diseases | Macrophage Activation Syndrome | Lipid Storage Myopathy | Stargardt Disease | Thyroid Hormone Resistance | McCune-Albright Syndrome | Pure Autonomic Failure | Hyperinsulinemia | Pilomatrix Carcinoma | Kleine-Levin Syndrome | Gingivitis | Systemic Lupus Erythematosus | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Achondrogenesis | Erythematotelangiectatic Rosacea | Myotonia | Majeed Syndrome | Congenital Hereditary Endothelial Dystrophy Type II | Intestinal Obstruction | Facioscapulohumeral Muscular Dystrophy Type 1 | Insulinoma | Gynecomastia | Protein C Deficiency | Congenital Myasthenic Syndrome | Schaaf-Yang Syndrome | Weill-Marchesani Syndrome | Episodic Ataxia | Generalized Epilepsy And Paroxysmal Dyskinesia | Autism | Kaposiform Hemangioendothelioma | Hyperlipidemia | Glutathione Synthetase Deficiency | Thyroid Dyshormonogenesis | Ectodermal Dysplasia | Blepharo-cheilo-odontic Syndrome | Fibromuscular Dysplasia | Ventricular Septal Defect | Crimean-Congo Hemorrhagic Fever | Hepatitis, Autoimmune | Dystonia-parkinsonism, X-linked | Hypersensitivity | Corticobasal Syndrome | Alexander Disease | Hamartoma | Phenylketonuria | Aceruloplasminemia | Noonan Syndrome-like Disorder With Loose Anagen Hair | Cholestasis, Intrahepatic | Trismus-pseudocamptodactyly Syndrome | Renal Tubular Acidosis | Leukodystrophies | Nanophthalmos | Stroke, Hemorrhagic | Craniolenticulosutural Dysplasia | IgA Nephropathy | Panuveitis | Pseudomyxoma Peritonei | Cherubism | Purpura | Adenosine Deaminase Deficiency | Anal Fissure | Melnick-Needles Syndrome | Jalili Syndrome | Diabetic Macular Edema | Leukoplakia | Galactosemia | Lentigo | Congenital Hemolytic Anemia | Distal Spinal Muscular Atrophy | Robinow Syndrome | Kohlschutter-Tonz Syndrome | Sclerocornea | Pouchitis | Migraine | Glycogen Storage Disease Type 4 | Antenatal Bartter Syndrome Type 1 | Prostatitis | Tardive Dyskinesia | Charcot-Marie-Tooth Disease, Type 2 | Lyme Disease | Delayed Sleep Phase Syndrome | Toxoplasmosis | Renpenning Syndrome | Hypobetalipoproteinemias | Coffin-Siris Syndrome | Adams-Oliver Syndrome | Endocarditis | Parkinson's Disease | Dent Disease | Sclerosteosis | Oligodendroglioma | Microcephaly, Seizures, And Developmental Delay | Bloom Syndrome | Congenital Torticollis | Spinocerebellar Ataxia Type 17 | Osteogenesis Imperfecta Type VI | Glucagonoma | Pendred Syndrome | Anovulation | Emery-Dreifuss Muscular Dystrophy | Frontotemporal Dementia | IMAGe Syndrome | Lattice Corneal Dystrophy Type 1 | Hereditary Coproporphyria | Ganglioneuroma | Chudley-McCullough Syndrome | Primary Lateral Sclerosis | Familial Digital Arthropathy-brachydactyly | Epithelioid Hemangioma | Stevens-Johnson Syndrome | Omenn Syndrome | Combined Malonic And Methylmalonic Acidemia | Epilepsy, Generalized | Vitreoretinal Degeneration, Snowflake Type | Congenital Disorders Of Glycosylation | Relapsing Polychondritis | Acute Lung Injury | Myasthenia Gravis | Smith-Lemli-Opitz Syndrome | Language Disorders | CHARGE Syndrome | Spinocerebellar Ataxia Type 5 | CDKL5 Deficiency Disorder | Autonomic Nervous System Disorders | Jawad Syndrome | Wagner Disease | Metanephric Adenoma | Gastrointestinal Disorders | IgA Deficiency | Gangliosidosis | Necrobiosis Lipoidica | Cold-induced Sweating Syndrome | Hypertension, Pulmonary | Cardiomyopathy, Dilated, 1L | Myofibromatosis | Lathosterolosis | Optic Nerve Hypoplasia, Bilateral | Hypolipoproteinemia | Anemia | Tetraplegia | Amelanotic Melanoma | X-linked Acrogigantism | Hyperglycemia | GNE Myopathy | Neuropathy | Seasonal Mood Disorder | Sarcomatoid Carcinoma Of The Lung | Schwartz-Jampel-Aberfeld Syndrome | Anencephaly | Rheumatic Heart Disease | Hepatitis E | Urethritis | Acromegaly | Obsessive-compulsive Disorder | Ileitis | Diastrophic Dysplasia | Crisponi Syndrome | Microphthalmia | Splenomegaly | Schnyder Crystalline Corneal Dystrophy | Usher Syndrome Type II | Measles | Palmoplantar Keratoderma | Arthritis, Psoriatic | Peripheral Neuropathy | Ollier Disease | Familial Male-limited Precocious Puberty | Blomstrand Osteochondrodysplasia | Acrodysostosis | Norrie Disease | Blastoma, Pleuropulmonary | Down Syndrome | Lipodystrophy | Renal Hypouricemia | Intracerebral Hemorrhage | Chromosome 9q34.3 Deletion Syndrome | Guanidinoacetate Methyltransferase Deficiency | Spinocerebellar Ataxia Type 14 | Epidermolysis Bullosa Dystrophica | Myoclonus | Epidermodysplasia Verruciformis | Sporadic Hemiplegic Migraine | Tularemia | Kindler Syndrome | Asphyxia Neonatorum | Fukuyama Congenital Muscular Dystrophy | Colitis, Lymphocytic | Anorexia Nervosa | Fontaine Progeroid Syndrome | Metaphyseal Chondrodysplasia, Schmid Type | Autoimmune Disease | Hypotrichosis | Non-Hodgkin Lymphoma | Spondyloarthritis | Persistent Hyperplastic Primary Vitreous | Coronary Restenosis | Vitamin D Deficiency | Spinal And Bulbar Muscular Atrophy | Pseudo-pseudohypoparathyroidism | Cryptosporidiosis | Cervicitis | Myelofibrosis | Optic Neuritis | Infantile Nephropathic Cystinosis | Eclampsia | Schistosomiasis | Spondylosis | Spinocerebellar Ataxia Type 42 | Blepharophimosis Syndrome | Fuchs Dystrophy | Viral Meningitis | Johanson-Blizzard Syndrome | Keratosis, Actinic | Hepatic Steatosis | Nephronophthisis | Polycythemia Vera | Sensory Neuropathy | Takayasu's Arteritis | Antiphospholipid Syndrome | Metabolic Syndrome | Spastic Paraplegia Type 7 | Thyroiditis | Rothmund-Thomson Syndrome | Pneumothorax | Bethlem Myopathy | Hyper IgE Syndrome | Castleman Disease | Familial Cerebral Amyloid Angiopathy | Melanoma, Uveal | Fahr Disease | Ataxia-ocular Apraxia 2 | Ichthyosis, X-linked | Citrullinemia | Snyder-Robinson Syndrome | Infertility, Male | Tatton-Brown-Rahman Syndrome | Reye Syndrome | Hypokalemic Periodic Paralysis | Hypogammaglobulinemia | Keratosis | Constipation | Erysipelas | Waardenburg Syndrome Type 2A | Infantile Spasm | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Myotonic Disorders | Pelizaeus-Merzbacher Disease | Hypopituitarism | Eosinophilic Asthma | Cystitis, Interstitial | Multicentric Carpotarsal Osteolysis Syndrome | Porphyria, Acute Intermittent | Microphthalmia, Syndromic 7 | Chylothorax, Congenital | Mitochondrial Encephalomyopathy | Stickler Syndrome | Anorectal Fistula | Hepatitis D | Sulfite Oxidase Deficiency | Hypertension | Infantile Refsum Disease | Aldosterone Synthase Deficiency | Corneal Edema | Hemolytic Uremic Syndrome | Scapuloperoneal Spinal Muscular Atrophy | Keloid | Multiple Sclerosis | Hyperammonemia | Beta-Propeller Protein-associated Neurodegeneration | Hypercholesterolemia | Bare Lymphocyte Syndrome | Netherton Syndrome | Fascioliasis | Ichthyosis | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Tay-Sachs Disease | LRBA Deficiency | Thrombophilia | Large Granular Lymphocytic Leukemia | Osteogenesis Imperfecta Type V | Peters-plus Syndrome | Aplasia Cutis Congenita | Pierre Robin Syndrome | Leri-Weill Dyschondrosteosis | Mixed Connective Tissue Disease | Malaria | Neuroleptic Malignant Syndrome | Waardenburg Syndrome Type 4A | Gastroschisis | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Brugada Syndrome 1 | Meniere's Disease | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Schnitzler Syndrome | Bulimia Nervosa | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Amelogenesis Imperfecta | Keratoacanthoma | Cerebellofaciodental Syndrome | Multiple Sclerosis, Relapsing-remitting | 3-methylglutaconic Aciduria Type IV | Early Infantile Epileptic Encephalopathy 28 | Hyperkeratosis | Arthritis | Sclerosteosis 2 | Albinism | Lattice Corneal Dystrophy | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Adenomatoid Tumor | Brenner Tumor | Chiari Malformation Type I | PHARC Syndrome | Facioscapulohumeral Muscular Dystrophy Type 2 | Myopia | Lafora Disease | Evans Syndrome | Diffuse Mesangial Sclerosis | Optic Neuropathy, Anterior Ischemic | Arteriosclerosis | Still Disease