Mast Cell Leukemia

About the Disease
Mast-Cell Leukemia, also known as mast cell leukemia, is related to mastocytosis, cutaneous and mast-cell sarcoma. An important gene associated with Mast-Cell Leukemia is KIT (KIT Proto-Oncogene, Receptor Tyrosine Kinase), and among its related pathways/superpathways are Innate Immune System and Signal Transduction. The drugs Mycophenolic acid and Fludarabine have been mentioned in the context of this disorder. Affiliated tissues include peripheral blood, bone marrow and spleen, and related phenotypes are Decreased viability and Decreased viability

Common Targets
Protein kinase C (nonspecified subtype) | Tubulin | FLT3 | PDE6D | KIT | TNFRSF8

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