Hepatocerebral Form Mitochondrial DNA Depletion Syndrome

About the Disease
Mitochondrial Dna Depletion Syndrome 3, also known as deoxyguanosine kinase deficiency, is related to mitochondrial dna depletion syndrome 6 and acute liver failure, and has symptoms including icterus, seizures and vomiting. An important gene associated with Mitochondrial Dna Depletion Syndrome 3 is DGUOK (Deoxyguanosine Kinase), and among its related pathways/superpathways is Peroxisomal lipid metabolism. Affiliated tissues include liver, eye and kidney, and related phenotypes are hyperreflexia and failure to thrive

Common Targets
MPV17 | TWNK | DGUOK | TFAM | POLG | SCYL1

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