Disease

Ichthyosis Hystrix, Curth-Macklin Type

About the Disease
Ichthyosis Hystrix, Curth-Macklin Type, also known as ichthyosis hystrix of curth-macklin, is related to ichthyosis and palmoplantar keratosis. An important gene associated with Ichthyosis Hystrix, Curth-Macklin Type is KRT1 (Keratin 1). Affiliated tissues include skin, and related phenotypes are ichthyosis and recurrent skin infections

Common Targets
KRT1

疾病靶点研报
Ichthyosis Hystrix, Curth-Macklin type

Note: If you'd like to get a target analysis report for Ichthyosis Hystrix, Curth-Macklin Type, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Ichthyosis Hystrix, Curth-Macklin Type at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.tech.

Other Diseases

Oculocutaneous Albinism Type 2 | Polyarteritis Nodosa | Osteogenesis Imperfecta | Hepatitis, Alcoholic | Monilethrix | Shprintzen-Goldberg Syndrome | POEMS Syndrome | Sorsby Fundus Dystrophy | Primary Progressive Nonfluent Aphasia | Acrodysostosis | Antenatal Bartter Syndrome Type 1 | Crigler-Najjar Syndrome | Cancer, Skin | Congenital Mirror Movements | Nemaline Myopathy 10 | 5-oxoprolinase Deficiency | Narcolepsy | Spondylocostal Dysostosis | Cardiofaciocutaneous Syndrome | Cardiac Sarcoidosis | Goiter | Metatropic Dysplasia | Spinocerebellar Ataxia Type 14 | Sclerosteosis | Spinal Muscular Atrophy Type 2 | Saethre-Chotzen Syndrome | Guillain-Barre Syndrome | Okihiro Syndrome | Infertility, Male | Vasculitis | Heimler Syndrome | Blastoma, Pleuropulmonary | T-cell Lymphoma, Subcutaneous Panniculitis-like | Congenital Bilateral Absence Of Vas Deferens | Hypoalbuminemia | Hashimoto Thyroiditis | Waardenburg Syndrome Type 2 | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Headache | Melanoma, Malignant | Split Hand-foot Malformation | Loeys-Dietz Syndrome Type 4 | Alpha-1 Antitrypsin Deficiency | Basal Ganglia Disease | Thrombophilia | Coenzyme Q10 Deficiency | Hyperparathyroidism, Primary | Tangier Disease | Dysgerminoma | Meningioma, Benign | Chediak-Higashi Syndrome | Kidney Stones | Reye Syndrome | Hemosiderosis | Hypopituitarism | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Cerebellar Ataxia, Cayman Type | Retinitis | Allan-Herndon-Dudley Syndrome | Urethritis | Membranous Nephropathy | Leri Pleonosteosis | Duane Retraction Syndrome | Hyperbilirubinemia | Macrodactyly | Arteriovenous Malformations | Muscular Dystrophy | Cherubism | Myoclonus | Tumoral Calcinosis | Encephalocele | Oculocutaneous Albinism Type 1 | Schistosomiasis Mansoni | Tricho-hepato-enteric Syndrome | Corneal Dystrophy | Wolfram Syndrome | Periodontitis | Renpenning Syndrome | Central Pain Syndrome | Iron Overload | Gastroschisis | Mitochondrial Cytopathy | Encephalopathy, Ethylmalonic | Spondylo-ocular Syndrome | Cardiomyopathy, Restrictive | Early Infantile Epileptic Encephalopathy | Alstrom Syndrome | Eiken Syndrome | Takenouchi-Kosaki Syndrome | Hereditary Xerocytosis | Occipital Neuralgia | Carcinoma, Signet Ring Cell | Asthma, Exercise-induced | Obsessive-compulsive Disorder | Hepatitis A | Fibrillation, Atrial | Paraganglioma, Carotid Body | Pre-eclampsia | Spinocerebellar Ataxia Type 31 | Autoimmune Hemolytic Anemia | Liver Failure | Blastomycosis | Hereditary Inclusion Body Myopathy | Cancer, Breast | Myositis | Esophagitis | Cutaneous Angiosarcoma | Uremia | Wilson's Disease | Oculocutaneous Albinism Type 4 | Multiple Epiphyseal Dysplasia | Generalized Epilepsy With Febrile Seizures Plus | Arthritis, Psoriatic | Meleda Disease | Juvenile Xanthogranuloma | Zollinger-Ellison Syndrome | Myelomeningocele | Pyruvate Carboxylase Deficiency Disease | Progressive Familial Intrahepatic Cholestasis | Lung Diseases | Non-epidermolytic Palmoplantar Keratoderma | Non-Langerhans Cell Histiocytosis | Intermittent Claudication | Cold-induced Sweating Syndrome | Transthyretin-related Amyloidosis | Glucagonoma | Dupuytren Disease | Osteogenesis Imperfecta Type VI | Raine Syndrome | Choroiditis | Polycythemia Vera | Infantile Liver Failure Syndrome 1 | Delayed Sleep Phase Syndrome | Williams Syndrome | Pyelonephritis | Hypertension, Pulmonary | Osteochondroma | Gingivitis | Extramammary Paget's Disease | GLUT1 Deficiency Syndrome | Spinocerebellar Ataxia Type 38 | Premature Ejaculation | Wolff-Parkinson-White Syndrome | Spinocerebellar Ataxia Type 2 | Colitis, Lymphocytic | PHARC Syndrome | Leukoencephalopathy, Progressive Multifocal | Amblyopia | Cutis Laxa | Uveitis, Anterior | Gynecomastia | Hodgkin Lymphoma | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Progressive Familial Intrahepatic Cholestasis Type 1 | Pernicious Anemia | Leukocyte Adhesion Deficiency Type 1 | Hoyeraal-Hreidarsson Syndrome | Usher Syndrome Type IIC | Congenital Absence Of Vas Deferens | Infantile Neuroaxonal Dystrophy | Gangliosidosis | Syndactyly | Spinocerebellar Ataxia Type 10 | Liver Diseases | Hamartoma | Hepatitis, Autoimmune | Pigment Dispersion Syndrome | Dementia | Craniopharyngioma | Larsen Syndrome | Exostoses | Nestor-Guillermo Progeria Syndrome | Hydrocephalus, Normal Pressure | Thyroid Hormone Resistance | Nasodigitoacoustic Syndrome | Cenani-Lenz Syndactyly Syndrome | Menetrier Disease | Rhizomelic Chondrodysplasia Punctata | Acrodermatitis Enteropathica | Cornelia De Lange Syndrome | Brachial Plexus Neuropathy | Glycogen Storage Disease Type 0, Muscle | Infantile Nephropathic Cystinosis | Dysmorphophobia | Retinal Diseases | Scapuloperoneal Myopathy, X-linked Dominant | Familial Retinal Arterial Macroaneurysm | Basal Cell Nevus Syndrome | Optic Neuropathy, Anterior Ischemic | Woodhouse-Sakati Syndrome | Cockayne Syndrome | Fetal Akinesia Deformation Sequence | Exocrine Pancreatic Insufficiency | Lipoma | Behavioral Variant Of Frontotemporal Dementia | Brooke-Spiegler Syndrome | CHARGE Syndrome | Charcot-Marie-Tooth Disease Type 4E | Frontometaphyseal Dysplasia | X-linked Creatine Transporter Deficiency | Pitt-Hopkins Syndrome | Renal Hypouricemia | Hidradenitis Suppurativa | Nemaline Myopathy | Multiple Myeloma | Prolymphocytic Leukemia | Huntington's Disease | Stuttering | Peripheral T-cell Lymphoma | Richter's Syndrome | Pulverulent Zonular Cataract | Erythema Multiforme | Vogt-Koyanagi-Harada Syndrome | Incontinentia Pigmenti | Early Infantile Epileptic Encephalopathy 1 | CREST Syndrome | Congenital Dysfibrinogenemia | Arthrogryposis | Desmosterolosis | 3-methylglutaconic Aciduria Type IV | Sialidosis | Charcot-Marie-Tooth Disease Type 4D | Prune Belly Syndrome | Hereditary Spastic Paraplegia | Osteoporosis, Postmenopausal | Hyperparathyroidism | Granular Corneal Dystrophy | Tyrosinemia | LMNA-related Congenital Muscular Dystrophy | Danon Disease | Lymphoma, B-cell | Erdheim-Chester Disease | Primary Hyperoxaluria | Hemophagocytic Lymphohistiocytosis | Fetal Alcohol Syndrome | Pure Red Cell Aplasia | Crohn's Disease | Chondrosarcoma | Microtia | Glioblastoma | Familial Male-limited Precocious Puberty | Alopecia Areata | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | WAGR Syndrome | Myofibromatosis | Encephalopathy | Adrenomyeloneuropathy | Congestive Heart Failure | Infantile Spasm | DEND Syndrome | Neurodermatitis | Pain | Renal Oncocytoma | D-2-Hydroxyglutaric Aciduria | Enterocolitis, Necrotizing | Sezary Syndrome | Anorectal Malformations | Dysplastic Nevus | Mast Cell Leukemia | Corneal Neovascularization | Anemia | Familial Glucocorticoid Deficiency | Celiac Disease | Autism Spectrum Disorders | Hypolipoproteinemia | Silicosis | Hydrops Fetalis | Vici Syndrome | Leishmaniasis, Visceral | Globozoospermia | Conduct Disorder | NGLY1 Deficiency | Dominant Optic Atrophy | Cardiac Arrest | Rhinitis | Schizophrenia | Non-Hodgkin Lymphoma | Sialoadenitis | Anovulation | Alopecia Totalis | Chronic Myeloid Leukemia | VEXAS Syndrome | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Psoriasis | Hypokalemia | Chondrodysplasia Punctata 1, X-linked Recessive | DOCK8 Immunodeficiency Syndrome | Meconium Ileus | Lissencephaly 2 | Snyder-Robinson Syndrome | Episodic Ataxia | Leber Congenital Amaurosis | Hepatitis, Chronic | Spinocerebellar Ataxia Type 8 | Jawad Syndrome | Melanoma | Greenberg Dysplasia | Sweet Syndrome | Chronic Idiopathic Myelofibrosis | Familial Pheochromocytoma-paraganglioma | Nicotine Dependence | Glomerulonephritis, Membranoproliferative | Hyperbilirubinemia, Neonatal | Argininosuccinic Aciduria | Milk Allergy | Thin Basement Membrane Disease | Paroxysmal Kinesigenic Dyskinesia | Cranioectodermal Dysplasia | Eccrine Porocarcinoma | Dengue Shock Syndrome | Placenta Previa | Hypertensive Retinopathy | Lymphopenia | Leprosy | Camptocormia | Harlequin Ichthyosis | Hereditary Mixed Polyposis Syndrome | Rubeosis Iridis | Cerebral Cavernous Malformations | Epidermolysis Bullosa Simplex, Generalized | Gallstones | Persistent Hyperplastic Primary Vitreous | Oguchi Disease-2 | Ovarian Hyperstimulation Syndrome | Optic Neuritis | Chronic Kidney Disease | Glycogen Storage Disease Type 3 | Cartilage Disorders | Epidermal Nevus Syndrome | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Gastrointestinal Disorders | Sarcoidosis, Pulmonary | Empyema | Thanatophoric Dysplasia | Bronchiolitis | Ghosal Syndrome | Syphilis | Myelitis | Osteogenesis Imperfecta Type I | Pemphigus | Nanophthalmos | Charcot-Marie-Tooth Disease, Type 2 | Desbuquois Syndrome | Long QT Syndrome Type 2 | Arthritis, Reactive | Depression | Alopecia | Sturge-Weber Syndrome | Frontotemporal Dementia | Cole-Carpenter Syndrome | Tylosis With Esophageal Cancer | Aplasia Cutis Congenita | Congenital Sodium Diarrhea | Endometritis | Ichthyosis, X-linked | Sitosterolemia | Bullous Pemphigoid | Multisystemic Smooth Muscle Dysfunction Syndrome | Pulmonary Vein Stenosis | Charcot-Marie-Tooth Disease Axonal Type 2N | Beare-Stevenson Syndrome | Carbonic Anhydrase VA Deficiency | Fibronectin Glomerulopathy | Basal Ganglia Cerebrovascular Disease | 3-methylglutaconic Aciduria Type I | Lattice Corneal Dystrophy Type 1 | Gitelman Syndrome | Familial Episodic Pain Syndrome | Pompe Disease | Fragile X Syndrome | Neuroma | Exfoliative Dermatitis | Congenital Primary Aphakia | Hypertension, Portal | Trichomegaly | Microphthalmia, Syndromic 7 | Demyelinating Diseases | Prurigo Nodularis | Amish Infantile Epilepsy Syndrome | Cholera | Glycogen Storage Disease Type 4 | Carcinoid Tumor | Lipid Storage Diseases | Galactosialidosis | Wiskott-Aldrich Syndrome | Dermatomyositis | Hypobetalipoproteinemias | Nephrosclerosis | Myeloid Leukemia | Cardiomyopathy, Hypertrophic | Plasma Cell Leukemia | Disseminated Superficial Actinic Porokeratosis | Sensory Neuropathy | Spinocerebellar Ataxia Type 17 | HUPRA Syndrome | Obesity, Morbid | Discoid Lupus Erythematosus | Erectile Dysfunction | Tardive Dyskinesia | Spondyloperipheral Dysplasia