Disease

Gastroschisis

About the Disease
Gastroschisis, also known as laparoschisis, is related to ileus and nutritional deficiency disease. An important gene associated with Gastroschisis is AEBP1 (AE Binding Protein 1), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Bupivacaine and Acetaminophen have been mentioned in the context of this disorder. Affiliated tissues include small intestine, liver and lung, and related phenotypes are gastroschisis and intestinal atresia

Common Targets
CSK | GNB3 | CD83 | ICAM1 | ICAM4 | CCDC88B | ATG5 | MAP3K14 | PAG1 | ADD1 | RORA | NOS3 | ICAM5 | F5 | GPR183 | B2M | PTPRC

疾病靶点研报
Gastroschisis

Note: If you'd like to get a target analysis report for Gastroschisis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Gastroschisis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Mitochondrial Myopathy | Sclerocornea | Protein S Deficiency | Pulmonary Stenosis | Ulcerative Colitis | Panniculitis | Crisponi Syndrome | Acrodermatitis | Congenital Heart Defects | Hypertension, Renovascular | Hypersomnia | Demyelinating Diseases | Blepharo-cheilo-odontic Syndrome | Esthesioneuroblastoma | Blue Nevus | Acute Myeloid Leukemia | Pulverulent Zonular Cataract | Bainbridge-Ropers Syndrome | Cardiomyopathy, Peripartum | Combined Deficiency Of Factor V And Factor VIII | Pleomorphic Xanthoastrocytoma | Smith-Kingsmore Syndrome | Porphyria Cutanea Tarda | Central Retinal Artery Occlusion | Smoldering Myeloma | Peripheral T-cell Lymphoma | Carbamoyl Phosphate Synthetase I Deficiency | Poikiloderma With Neutropenia | Necrobiosis Lipoidica | Microphthalmia | Ornithine Transcarbamylase Deficiency | Leigh Syndrome | Pathological Gambling | Paraganglioma, Carotid Body | Trichomegaly | Congenital Stromal Corneal Dystrophy | Crouzon Syndrome With Acanthosis Nigricans | Pseudohypoaldosteronism | Congenital Nystagmus | Idiopathic Pulmonary Fibrosis | Endophthalmitis | Amelanotic Melanoma | Charcot-Marie-Tooth Disease, Type 1A | Pemphigus | Ectopia Lentis, Isolated, Autosomal Recessive | Porphyria, Acute Intermittent | Vaginitis | Limb Girdle Muscular Dystrophy | Tracheal Disorders | Hypotonia-cystinuria Syndrome | Sandhoff Disease | Alstrom Syndrome | Kindler Syndrome | LMNA-related Congenital Muscular Dystrophy | Atrial Septal Defect | Tyrosinemia Type 2 | Macular Degeneration | Intestinal Pseudo-obstruction | Asperger Syndrome | Gastroschisis | Gastroenteritis | X-linked Charcot-Marie-Tooth Disease | Lipid Storage Diseases | Autonomic Neuropathy | Isovaleric Acidemia | Endocarditis | Smith-Magenis Syndrome | Hypertension | Melanocytic Nevus | Renal Oncocytoma | Ataxia-ocular Apraxia 2 | Hypermetropia | Atelosteogenesis Type 1 | Hypodontia | Lymphomatoid Granulomatosis | Benign Familial Pemphigus | Metabolic Syndrome | Mitochondrial DNA Depletion Syndrome 13 | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Pernicious Anemia | Angina Pectoris | Alopecia | Proteus Syndrome | Alpha-1 Antitrypsin Deficiency | Micro Syndrome | Trismus-pseudocamptodactyly Syndrome | Stroke, Ischemic | Syncope | Infectious Diarrhea | Budd-Chiari Syndrome | Varicocele | Familial Thoracic Aortic Aneurysm | Neurodevelopmental Disorders | Nevus | Renal Tubular Dysgenesis | Colitis, Lymphocytic | Chronic Periodontitis | Goiter | Juvenile Myoclonic Epilepsy | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Vici Syndrome | Seasonal Mood Disorder | Chromosome 16p11.2 Deletion Syndrome | Chronic Neutrophilic Leukemia | Osteomalacia | Barakat Syndrome | B-cell Prolymphocytic Leukemia | Cholestasis, Intrahepatic | Niemann-Pick Disease, Type B | Multiple Hamartoma Syndrome | LEOPARD Syndrome | Woodhouse-Sakati Syndrome | Rickets | Vascular Calcification | Rotor Syndrome | Distal Spinal Muscular Atrophy | Acute Motor Axonal Neuropathy | Insulinoma | Progressive Familial Intrahepatic Cholestasis Type 3 | Schwannomatosis | Multisystemic Smooth Muscle Dysfunction Syndrome | Paroxysmal Kinesigenic Dyskinesia | Sclerosteosis 2 | Lafora Disease | Meningioma | Anti-glomerular Basement Membrane Disease | Esophageal Carcinoma | Polycystic Liver | Photosensitivity | Platelet Disorders | Premature Ejaculation | Osteogenesis Imperfecta Type I | Blepharophimosis Syndrome | Acrodermatitis Enteropathica | Aldosterone Deficiency | Pemphigoid | Sporadic Inclusion Body Myositis | Sitosterolemia | Ovarian Sex Cord-stromal Tumor | Lathosterolosis | Peritonitis | Epilepsy, Generalized | Carcinoma, Signet Ring Cell | Retinal Dystrophy, Early-onset Severe | Phenylketonuria | Genitopatellar Syndrome | Chudley-McCullough Syndrome | Congenital Poikiloderma | Myositis, Focal | Neuromyotonia | Birt-Hogg-Dube Syndrome | Sick Sinus Syndrome | Myasthenia Gravis | Seizures-scoliosis-macrocephaly Syndrome | Gallstones | Papilledema | Chordoma | Prolactinoma | Urea Cycle Disorder | Aceruloplasminemia | Fetal Alcohol Syndrome | Hyperlipidemia, Familial Combined | Multiple Sclerosis, Primary Progressive | Zollinger-Ellison Syndrome | Myoclonus-dystonia Syndrome | Rhabdomyosarcoma, Alveolar | Spinocerebellar Ataxia Type 15 | Congenital Myasthenic Syndrome | Encephalopathy, Glycine | Schwartz-Jampel-Aberfeld Syndrome | Multifocal Motor Neuropathy | Papillon-Lefevre Syndrome | Arteriosclerosis | Frontometaphyseal Dysplasia | Non-proliferative Diabetic Retinopathy | Myocardial Infarction | Larsen Syndrome | Borderline Personality Disorder | Hypospadias | Ocular Albinism Type 1 | Hepatoblastoma | Renal Hypouricemia | DOCK8 Immunodeficiency Syndrome | Congenital Hereditary Endothelial Dystrophy Type I | Brachial Plexus Neuropathy | Iron Deficiency Anemia | Neurotoxicity | Hyperkalemic Periodic Paralysis | Autism | Purpura, Thrombotic Thrombocytopenic | Hypokalemia | Hypertension, Essential | Tremor | Kabuki Syndrome | T-cell Leukemia | Bone Giant Cell Tumor | Waardenburg Syndrome Type 4A | Thyroid Dyshormonogenesis | Agranulocytosis | Acanthosis Nigricans | T-cell Prolymphocytic Leukemia | Anosmia, Congenital | Cerebellar Ataxia, Cayman Type | Trichothiodystrophy | Fetal And Neonatal Alloimmune Thrombocytopenia | Aicardi-Goutieres Syndrome | Amebiasis | Maternally Inherited Diabetes And Deafness | Gray Platelet Syndrome | Incontinentia Pigmenti | Pulmonary Sclerosing Hemangioma | Thrombasthenia | Schistosomiasis Mansoni | Globozoospermia | Gigantism | Oculocutaneous Albinism | Veno-occlusive Disease | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Dystonia-parkinsonism, X-linked | Dupuytren Disease | Multiple Myeloma | Pleural Tuberculosis | Azoospermia | Early Infantile Epileptic Encephalopathy 28 | Atrioventricular Septal Defect | Optic Neuritis | Stroke, Hemorrhagic | Pseudohypoparathyroidism Type 1C | VEXAS Syndrome | Gyrate Atrophy Of The Choroid And Retina | Ophthalmoplegia | Microcephaly | Scabies | Lung Diseases | Spinocerebellar Ataxia Type 12 | Thrombophlebitis | Noonan Syndrome | Cancer, Prostate | Giant Cell Glioblastoma | Keratoconjunctivitis | Acute Generalized Exanthematous Pustulosis | Diastrophic Dysplasia | Congenital Ichthyosiform Erythroderma | Congenital Central Hypoventilation Syndrome | Ependymoma | Proctitis | Nemaline Myopathy | Neuropathy | Diabetes Type 1 | Robinow Syndrome | Pigment Dispersion Syndrome | Chanarin-Dorfman Syndrome | Retinoschisis | Speech Disorders | Congenital Primary Aphakia | Non-Hodgkin Lymphoma | Stiff-man Syndrome | Exfoliative Dermatitis | Mannosidase Deficiency Diseases | Malaria, Cerebral | Influenza | Tyrosine Hydroxylase Deficiency | Spinocerebellar Ataxia Type 23 | Hypokalemic Periodic Paralysis | Pouchitis | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Mitochondrial DNA Depletion Syndrome | Relapsing Polychondritis | Dowling-Degos Disease | Methemoglobinemia | Lymphedema | Hyperkeratosis | Measles | Chylomicron Retention Disease | Desmosterolosis | Episodic Ataxia Type 2 | Congenital Afibrinogenemia | Neuroleptic Malignant Syndrome | Polymyositis | Ichthyosis, X-linked | Infantile Nephropathic Cystinosis | Kleine-Levin Syndrome | Uremia | Retinitis Pigmentosa | Lymphoproliferative Disorders | Niemann-Pick Disease | Hyperoxaluria | Megaloblastic Anemia | Eccrine Porocarcinoma | Mitochondrial Cytopathy | Stevens-Johnson Syndrome | Diabetes | Pompe Disease | Rhizomelic Chondrodysplasia Punctata | Bullous Pemphigoid | Shock, Cardiogenic | Paraplegia | Tietze Syndrome | Acrocallosal Syndrome | LRBA Deficiency | Alpha-thalassemia Myelodysplasia Syndrome | Glycogen Storage Disease Type 4 | Nephronophthisis | CDKL5 Deficiency Disorder | Saethre-Chotzen Syndrome | H Syndrome | Gastroenteritis, Eosinophilic | Iron Overload | Cystinuria | Onchocerciasis | Glaucoma, Congenital | Acute Lung Injury | Corneal Dystrophies, Hereditary | Dyslexia | Frontotemporal Dementia | Apert Syndrome | Hypothyroidism | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Alpha-mannosidosis | CHOPS Syndrome | Lyme Disease | Thrombotic Microangiopathy | Familial Hyperaldosteronism | Fanconi Syndrome | Rubinstein-Taybi Syndrome | Keratosis | Brugada Syndrome 1 | Canavan Disease | Atopic Dermatitis | Basal Ganglia Disease, Biotin-responsive | Fatty Aldehyde Dehydrogenase Deficiency | Pneumonia, Mycoplasma | Bernard-Soulier Syndrome | Language Disorders | Tatton-Brown-Rahman Syndrome | Zimmermann-Laband Syndrome | Fibronectin Glomerulopathy | Currarino Syndrome | Cataplexy | C3 Glomerulonephritis | Primary Familial Brain Calcification | Metabolic Diseases | Cantu Syndrome | Coronary Artery Disease | Netherton Syndrome | Obesity, Morbid | Ollier Disease | Uterine Leiomyoma | Bartsocas-Papas Syndrome | Hemochromatosis | Malignant Fibrous Histiocytoma | Retinal Vasculitis | Stroke | Retinal Coloboma | Blau Syndrome | Hydronephrosis | Motor Neuron Diseases | Porphyria | Hypolipoproteinemia | Thromboembolism | Rhinitis | Ellis-Van Creveld Syndrome | Neurodermatitis | Inflammatory Linear Verrucous Epidermal Nevus | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Sleep Apnea, Central | Postaxial Polydactyly | Pterygium | Macular Corneal Dystrophy | Panic Disorder | Esophageal Motility Disorders | Focal Facial Dermal Dysplasia | Fucosidosis | Richter's Syndrome | Trichuriasis | Thyrotoxic Periodic Paralysis | Angioedema | Neurodegeneration With Brain Iron Accumulation | Dengue Hemorrhagic Fever | Cystinosis | Primary Aldosteronism | Hemolytic Anemia | 3-methylcrotonyl-CoA Carboxylase Deficiency | Gitelman Syndrome | Takayasu's Arteritis | Primary Carnitine Deficiency | Cholera | Nicotine Addiction | Spinocerebellar Ataxia Type 38 | Osteogenesis Imperfecta | Microphthalmia, Syndromic 7 | Osteogenesis Imperfecta Type III | Macrodactyly | Hypocalcemia | Congenital Absence Of Vas Deferens | Waardenburg Syndrome | Meier-Gorlin Syndrome | Brooke-Spiegler Syndrome | Pulmonary Capillary Hemangiomatosis | Hereditary Coproporphyria