Carotid Artery Disease

About the Disease
Carotid Artery Disease, also known as carotid artery diseases, is related to arteries, anomalies of and carotid stenosis, and has symptoms including angina pectoris, chest pain and edema. An important gene associated with Carotid Artery Disease is SLC39A2 (Solute Carrier Family 39 Member 2), and among its related pathways/superpathways are Diseases of hemostasis and Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs). The drugs Exenatide and Simvastatin have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and lung, and related phenotypes are Increased free cholesterol and homeostasis/metabolism

Common Targets
HMGCR | CDKN2B-AS1 | DPP4 | G3569 | NOS2 | FASLG | CX3CR1 | PPARG | PHACTR1 | VWF

Note: If you'd like to get a target analysis report for Carotid Artery Disease, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Carotid Artery Disease at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Hypercalcemia | Ectopia Lentis, Isolated, Autosomal Recessive | Bursitis | Generalized Epilepsy And Paroxysmal Dyskinesia | Polycystic Ovary Syndrome | Micropenis | Stroke, Hemorrhagic | Ichthyosis Hystrix, Curth-Macklin Type | Tylosis With Esophageal Cancer | Hypertension, Portal | Gaucher Disease | Trismus-pseudocamptodactyly Syndrome | Prune Belly Syndrome | Hypotrichosis Simplex | Feingold Syndrome | Fibrosis | Esthesioneuroblastoma | Spinocerebellar Ataxia Type 17 | Meckel-Gruber Syndrome | Rift Valley Fever | Goldenhar Syndrome | Cancer, Bladder | Oculocutaneous Albinism Type 1 | Carney-Stratakis Syndrome | Retinal Degeneration | Acrocallosal Syndrome | Microcephalic Primordial Dwarfism | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Hyperparathyroidism, Primary | Anthrax | Idiopathic Pulmonary Fibrosis | Vestibular Disease | Acute Motor Axonal Neuropathy | Sleep Apnea, Obstructive | Tremor | Usher Syndrome Type IIC | Rash | Meniere's Disease | Multifocal Motor Neuropathy | Primary Hyperoxaluria | Scoliosis | Carbamoyl Phosphate Synthetase I Deficiency | Lathosterolosis | Christianson Syndrome | Blue Rubber Bleb Nevus Syndrome | Progressive Familial Intrahepatic Cholestasis | Spinocerebellar Ataxia Type 8 | Renal Tubular Acidosis | Schwannoma | Homocystinuria | Corneal Dystrophy | Neovascular Glaucoma | Spondylolisthesis | ACTH-independent Macronodular Adrenal Hyperplasia | Tuberculous Meningitis | Coma | Gout | Congenital Hereditary Endothelial Dystrophy Type I | Kaposiform Hemangioendothelioma | Epilepsy | Avian Influenza | Congenital Torticollis | Waardenburg Syndrome Type 2A | Eczema | Bone Giant Cell Tumor | Connective Tissue Disorders | Congenital Ichthyosiform Erythroderma | Overactive Bladder | Bipolar Disorder | Papilledema | Hyperkeratosis | Hereditary Sensory And Autonomic Neuropathy | Hypodontia | Anemia | Psoriasis | Learning Disability | Occipital Neuralgia | Lattice Corneal Dystrophy | Granular Corneal Dystrophy | SAPHO Syndrome | DiGeorge Syndrome | Globozoospermia | Keratitis-ichthyosis-deafness Syndrome | Blepharitis | Pleurisy | Neurodevelopmental Disorders | Retinopathy Of Prematurity | Citrullinemia | Castleman Disease | Congenital Stromal Corneal Dystrophy | Low Tension Glaucoma | Sickle Cell Anemia | Trichuriasis | Epidermolysis Bullosa Simplex | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Retinitis Pigmentosa 3 | Hypersomnia | Cholera | Schamberg Disease | Meningioma | Charcot-Marie-Tooth Disease Type 4B1 | Pitt-Hopkins Syndrome | DRESS Syndrome | Nevus | High Molecular Weight Kininogen Deficiency | Imerslund-Grasbeck Syndrome | Non-small Cell Lung Cancer | Rolandic Epilepsy | Sclerosing Cholangitis | Autonomic Neuropathy | Charcot-Marie-Tooth Disease, Type 2C | Polyarteritis Nodosa | Dubin-Johnson Syndrome | Angiosarcoma | Hidradenitis Suppurativa | Myositis | Temtamy Preaxial Brachydactyly Syndrome | Kabuki Syndrome 2 | Cohen Syndrome | Heterotopic Ossification | Short-chain Acyl-CoA Dehydrogenase Deficiency | Kearns-Sayre Syndrome | Ophthalmia, Sympathetic | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Multiple Epiphyseal Dysplasia | Chromosome 17q21.31 Deletion Syndrome | Mitochondrial DNA Depletion Syndrome, Myopathic Form | Glycogen Storage Disease Type 0, Muscle | Fibrillation, Atrial | Methemoglobinemia Type IV | Chronic Mucocutaneous Candidiasis | Dengue Hemorrhagic Fever | Dystonia | Venous Insufficiency | Cerebral Amyloid Angiopathy | Urea Cycle Disorder | Cholestasis | Hemorrhage | Melanoma, Malignant | Alpha-thalassemia Myelodysplasia Syndrome | Lymphoma | Hypotonia-cystinuria Syndrome | Gestational Trophoblastic Disease | Charcot-Marie-Tooth Disease, Type 2 | Aicardi-Goutieres Syndrome | Diabetes Insipidus | Vitreoretinal Degeneration, Snowflake Type | Neurofibromatosis-Noonan Syndrome | Corneal Dystrophies, Hereditary | Corneal Ulcer | Dermatitis | Fraser Syndrome | Vogt-Koyanagi-Harada Syndrome | Blepharo-cheilo-odontic Syndrome | Oligoasthenoteratozoospermia | Migraine | Autoimmune Polyendocrinopathy Syndrome Type I | Loeys-Dietz Syndrome Type 4 | Protein S Deficiency | 3-methylcrotonyl-CoA Carboxylase Deficiency | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Pontocerebellar Hypoplasia Type 7 | Lymphoma, AIDS-related | Bronchiectasis | Farber Disease | Keratosis | Large Granular Lymphocytic Leukemia | Polycythemia Vera | Desmosterolosis | Optic Nerve Diseases | Cataplexy | Reflex Epilepsy | Oculodentodigital Dysplasia | Hereditary Folate Malabsorption | Dermatitis Herpetiformis | Achondrogenesis | Rhabdomyosarcoma, Alveolar | Pyruvate Decarboxylase Deficiency | Antley-Bixler Syndrome | Trichotillomania | Thyroiditis | Prolidase Deficiency | Transthyretin-related Amyloidosis | Motion Sickness | Bronchitis | Hereditary Inclusion Body Myopathy | Synovitis | Tibial Muscular Dystrophy | Acromesomelic Dysplasia | IMAGe Syndrome | Spondylometaphyseal Dysplasia | Oral Lichen Planus | Pseudohypoparathyroidism Type 1B | Ocular Albinism Type 1 | Nephropathy | Schizophrenia | Viral Meningitis | Leukemia-lymphoma, Adult T-cell | Phosphoglycerate Dehydrogenase Deficiency | Rhabdomyosarcoma, Embryonal | Optic Neuropathy | Congenital Afibrinogenemia | Twin-to-twin Transfusion Syndrome | Dystonia Musculorum Deformans | Prader-Willi Syndrome | Anxiety Disorders | X-linked Acrogigantism | Language Disorders | Stiff-man Syndrome | Peters-plus Syndrome | Mycosis Fungoides | Fibromuscular Dysplasia | Emery-Dreifuss Muscular Dystrophy | Spinocerebellar Ataxia Type 40 | Retinitis Pigmentosa | Galactosemia | Pearson Syndrome | Hypercholesterolemia | Knobloch Syndrome | Withdrawal Syndrome | Hereditary Spherocytosis | Meningioma, Benign | Ichthyosis, X-linked | Myoclonic Atonic Epilepsy | Primary Carnitine Deficiency | Mosaic Variegated Aneuploidy Syndrome 2 | Amenorrhea | Pseudohermaphroditism | Strabismus | Meleda Disease | Deafness, Dystonia, And Cerebral Hypomyelination | Nephronophthisis | Kidney Stones | Holoprosencephaly | Glutathione Synthetase Deficiency | Antisocial Personality Disorder | Autosomal Recessive Bestrophinopathy | Renal Medullary Carcinoma | Hypocalcemia | Hypolipoproteinemia | Donnai-Barrow Syndrome | FG Syndrome | Joubert Syndrome 2 | Methylmalonic Aciduria And Homocystinuria, CblC Type | Otosclerosis | Hidradenitis | Axenfeld-Rieger Syndrome | Pelizaeus-Merzbacher Disease | Intracerebral Hemorrhage | Heimler Syndrome | Immunoproliferative Disorders | Endocarditis | Cold Agglutinin Disease | Neurocutaneous Syndromes | Sarcoma, Ewing | Systemic Lupus Erythematosus | Hypogammaglobulinemia | Conjunctivitis, Allergic | Spondyloperipheral Dysplasia | Episodic Ataxia Type 2 | Apraxia | Exostoses | Chronic Myeloid Leukemia | Infertility, Male | Depression | Aneurysm, Abdominal Aortic | Vici Syndrome | Fetal Alcohol Syndrome | Waardenburg Syndrome Type 2E | Papillorenal Syndrome | Acute Anterior Uveitis | REM Sleep Behavior Disorder | Juvenile Myoclonic Epilepsy | Angina Pectoris | Dyslexia | Salla Disease | Zellweger Syndrome | Polyomavirus Nephropathy | Central Core Disease | Uveitis | Acral Lentiginous Melanoma | Granuloma Annulare | Whipple's Disease | Snyder-Robinson Syndrome | Gingivitis | Peripheral Neuropathy | Mountain Sickness | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Atelosteogenesis Type 2 | Erysipelas | Gastritis | Ileitis | Paget's Disease Of The Breast | Familial Hypobetalipoproteinemia | Periventricular Leukomalacia | GLUT1 Deficiency Syndrome | Progressive Encephalopathy-optic Atrophy Syndrome | Anosmia, Congenital | Dysfibrinogenemia | Chordoma | Schizophrenia, Paranoid | Hydronephrosis | Congenital Lipoid Adrenal Hyperplasia | Osteomyelitis | HELLP Syndrome | Hemimegalencephaly | Leukoencephalopathy, Progressive Multifocal | Glomerulonephritis, Membranous | Proctitis | Pierson Syndrome | Lymphangioleiomyomatosis | Wolman Disease | Thrombophlebitis | Insulin Resistance | Hereditary Multiple Exostoses | Angioimmunoblastic T-cell Lymphoma | Polyneuropathy | Alazami Syndrome | Myosin Storage Myopathy | Thyroid Dysgenesis | Cerebrotendinous Xanthomatosis | Liebenberg Syndrome | Guillain-Barre Syndrome | Leishmaniasis, Visceral | Cystinosis | Hypertension, Renovascular | Van Der Knaap Disease | Sporadic Hemiplegic Migraine | Presbyopia | Choriocarcinoma | Monilethrix | Marshall-Smith Syndrome | Inflammatory Myofibroblastic Tumor | Johanson-Blizzard Syndrome | Hyperhomocysteinemia | Dermatofibrosarcoma | Osteopathia Striata With Cranial Sclerosis | Epidermolysis Bullosa Simplex, Generalized | Charcot-Marie-Tooth Disease, Type 1A | Localized Scleroderma | Familial Hemiplegic Migraine | Thyrotoxic Periodic Paralysis | Seminoma | Neurocutaneous Melanocytosis | Keratoacanthoma | Histiocytic Sarcoma | Congenital Nephrotic Syndrome | Spinocerebellar Ataxia Type 42 | Arthrogryposis | Congenital Heart Defects | Cardiomyopathy, Peripartum | Cardiofaciocutaneous Syndrome | Atherosclerosis | Osteogenesis Imperfecta Type V | Glomerulonephritis, Membranoproliferative | Central Retinal Artery Occlusion | Congenital Myopathy | Leukoplakia, Oral | Dementia, Vascular | Kallmann Syndrome | Chondrodysplasia Punctata 2, X-linked Dominant | Distal Myopathy 2 | Ligneous Conjunctivitis | Riboflavin Transporter Deficiency Neuronopathy | Transcobalamin Deficiency | Iron Metabolism Disorders | Empyema | Charcot-Marie-Tooth Disease Type 3 | Coronary Restenosis | Hoyeraal-Hreidarsson Syndrome | Beta-Propeller Protein-associated Neurodegeneration | Bronchiolitis | Tangier Disease | Mucolipidosis | Adult Polyglucosan Body Disease | Neurocysticercosis | Hypoproteinemia, Hypercatabolic | Schizoaffective Disorder | Hyperthermia, Malignant | Exfoliative Dermatitis | Pre-eclampsia | Metatropic Dysplasia | Retinal Dystrophy | Leri-Weill Dyschondrosteosis | Coronary Heart Disease | Polymicrogyria | Hodgkin Lymphoma | Parkinson Disease 6, Autosomal Recessive Early-onset | Supravalvular Aortic Stenosis | Werner's Syndrome | Neuroblastoma | Bicuspid Aortic Valve | Pulmonary Veno-occlusive Disease | IgA Deficiency | Malnutrition | Congenital Generalized Lipodystrophy | Plasmacytoma | Tetraplegia | Granular Corneal Dystrophy Type 1 | Communication Disorders