Disease

Eczema

About the Disease
Dermatitis, also known as eczema, is related to irritant dermatitis and dermatitis herpetiformis, and has symptoms including exanthema and pruritus. An important gene associated with Dermatitis is FLG (Filaggrin), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Salicylic acid and Titanium dioxide have been mentioned in the context of this disorder. Affiliated tissues include skin, breast and t cells, and related phenotypes are immune system and hematopoietic system

Common Targets
CNTN5 | LCE1B | BTK | AMP-activated protein kinase (AMPK) | IL33 | IL22 | D2HGDH | TPM3 | SPINK5 | F2RL1 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | KCNN3 | VARS1 | OPRK1 | LCE3E | Melanin | OVOL1 | SKIC2 | PDE4B | IL2RA | SLC9A2 | EGFL8 | NR1H2 | TNFSF18 | FKBP1A | HLA-DMB | SNX27 | KLK5 | PHF11 | G7295 | TRAF3 | TYK2 | HCP5 | FLG | IFNGR1 | G1432 | SPRR2C | LINC00299 | DDX39B | RUNX3 | PIP5K1A | CTSS | BMX | SPRR3 | IL4R | G6352 | OAZ3 | AQP3 | RPUSD2 | LINC01149 | PPP3R2 | ETV6 | MSH5 | ABHD16A | NOTCH4 | CLK4 | PPP3CC | IL12RB1 | LCE2B | CD14 | BTNL2 | ARG1 | TSBP1-AS1 | HLA-DOB | MICB | IL-17 A/F heterodimer | LOC100287329 | IL-4 receptor | PPT2 | ADAD1 | G5595 | G7124 | G3605 | PBX2 | LY6G6D | SYK | TDRKH | AGPAT1 | SELP | ARNT | SFMBT1 | MIR155HG | NR3C1 | SERPINE1 | TSLP | CCL11 | RAD50 | NELFE | NUP210L | CYP2R1 | GSDMB | RTEL1 | Retinoid acid receptor (nonspecified subtype) | RARB | ZBTB1 | AIF1 | PTGDR2 | NFKBIL1 | VDR | G2064 | TRPV3 | IL18RAP | IL17F | STK19 | GABPB2 | RNF5 | Immunoglobulin E (IgE) | CD200R1 | IGFBP4 | Serine protease (nonspecified subtype) | TCHHL1 | IL2 | MBD3L1 | MICB-DT | NCR3 | IL10 | Sterol O-acyltransferase (ACAT) (nonspecified subtype) | SHE | ZNF365 | Janus Kinase (nonspecified subtype) | CLEC16A | G1956 | GC | EHMT2 | IL5RA | TCHH | TNK2 | IFNG | CSNK2B | SPHK1 | IFNAR1 | PRR5L | HRH1 | Cyclooxygenase (COX) (nonspecified subtype) | PGLYRP3 | TNXB | PPP3CB | PRKCQ | CYP27A1 | ARRDC1 | ALB | PPP3R1 | IL18R1 | SGCZ | HORMAD1 | KIF3A | PRUNE1 | Retinoid RXR receptor (nonspecified subtype) | IL6R | DEFB1 | FLG-AS1 | MRGPRX2 | IL1B | IL4 | JAK3 | IL-13 receptor | SLC9A4 | RARG | JAK1 | CSF2RB | TSBP1 | MICA | JAK2 | CYP27B1 | CTXND2 | G5347 | IL13 | PGLYRP4 | RAB13 | G3576 | IL18 | STAT5B | THRA | PRRC2A | GPSM3 | TXK | TAP2 | HMOX1 | RPRD2 | DUSP1 | CMA1 | NFKB1 | C2 | ADAR | SELE | NF-kappaB (NFkB) | LCE5A | KLK14 | RORC | BAG6 | ATF6B | MC1R | LCE1A | Protein Phosphatase 2B

疾病靶点研报
Eczema

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