Eczema

About the Disease
Dermatitis, also known as eczema, is related to irritant dermatitis and dermatitis herpetiformis, and has symptoms including exanthema and pruritus. An important gene associated with Dermatitis is FLG (Filaggrin), and among its related pathways/superpathways are Innate Immune System and MIF Mediated Glucocorticoid Regulation. The drugs Salicylic acid and Titanium dioxide have been mentioned in the context of this disorder. Affiliated tissues include skin, breast and t cells, and related phenotypes are immune system and hematopoietic system

Common Targets
CNTN5 | LCE1B | BTK | AMP-activated protein kinase (AMPK) | IL33 | IL22 | D2HGDH | TPM3 | SPINK5 | F2RL1 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | KCNN3 | VARS1 | OPRK1 | LCE3E | Melanin | OVOL1 | SKIC2 | PDE4B | IL2RA | SLC9A2 | EGFL8 | NR1H2 | TNFSF18 | FKBP1A | HLA-DMB | SNX27 | KLK5 | PHF11 | G7295 | TRAF3 | TYK2 | HCP5 | FLG | IFNGR1 | G1432 | SPRR2C | LINC00299 | DDX39B | RUNX3 | PIP5K1A | CTSS | BMX | SPRR3 | IL4R | G6352 | OAZ3 | AQP3 | RPUSD2 | LINC01149 | PPP3R2 | ETV6 | MSH5 | ABHD16A | NOTCH4 | CLK4 | PPP3CC | IL12RB1 | LCE2B | CD14 | BTNL2 | ARG1 | TSBP1-AS1 | HLA-DOB | MICB | IL-17 A/F heterodimer | LOC100287329 | IL-4 receptor | PPT2 | ADAD1 | G5595 | G7124 | G3605 | PBX2 | LY6G6D | SYK | TDRKH | AGPAT1 | SELP | ARNT | SFMBT1 | MIR155HG | NR3C1 | SERPINE1 | TSLP | CCL11 | RAD50 | NELFE | NUP210L | CYP2R1 | GSDMB | RTEL1 | Retinoid acid receptor (nonspecified subtype) | RARB | ZBTB1 | AIF1 | PTGDR2 | NFKBIL1 | VDR | G2064 | TRPV3 | IL18RAP | IL17F | STK19 | GABPB2 | RNF5 | Immunoglobulin E (IgE) | CD200R1 | IGFBP4 | Serine protease (nonspecified subtype) | TCHHL1 | IL2 | MBD3L1 | MICB-DT | NCR3 | IL10 | Sterol O-acyltransferase (ACAT) (nonspecified subtype) | SHE | ZNF365 | Janus Kinase (nonspecified subtype) | CLEC16A | G1956 | GC | EHMT2 | IL5RA | TCHH | TNK2 | IFNG | CSNK2B | SPHK1 | IFNAR1 | PRR5L | HRH1 | Cyclooxygenase (COX) (nonspecified subtype) | PGLYRP3 | TNXB | PPP3CB | PRKCQ | CYP27A1 | ARRDC1 | ALB | PPP3R1 | IL18R1 | SGCZ | HORMAD1 | KIF3A | PRUNE1 | Retinoid RXR receptor (nonspecified subtype) | IL6R | DEFB1 | FLG-AS1 | MRGPRX2 | IL1B | IL4 | JAK3 | IL-13 receptor | SLC9A4 | RARG | JAK1 | CSF2RB | TSBP1 | MICA | JAK2 | CYP27B1 | CTXND2 | G5347 | IL13 | PGLYRP4 | RAB13 | G3576 | IL18 | STAT5B | THRA | PRRC2A | GPSM3 | TXK | TAP2 | HMOX1 | RPRD2 | DUSP1 | CMA1 | NFKB1 | C2 | ADAR | SELE | NF-kappaB (NFkB) | LCE5A | KLK14 | RORC | BAG6 | ATF6B | MC1R | LCE1A | Protein Phosphatase 2B

Note: If you'd like to get a target analysis report for Eczema, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Eczema at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Congenital Dysfibrinogenemia | Hepatic Veno-occlusive Disease | Hemorrhoids | Lymphoproliferative Disorders | Autoimmune Autonomic Ganglionopathy | Hyperacusis | Zollinger-Ellison Syndrome | Trimethylaminuria | Demyelinating Diseases | Malaria, Cerebral | Spermatocele | Partington Syndrome | Charcot-Marie-Tooth Disease Type 2T | Snyder-Robinson Syndrome | Myopia | Genee-Wiedemann Syndrome | Osteogenesis Imperfecta Type V | T-cell Chronic Lymphocytic Leukemia | Martsolf Syndrome | Tyrosinemia Type 1 | Bronchiolitis | Discoid Lupus Erythematosus | Gastric Atrophy | Dyslexia | Pyruvate Decarboxylase Deficiency | Anorectal Fistula | Familial Mediterranean Fever | CREST Syndrome | Progressive External Ophthalmoplegia | Retinal Coloboma | Iron Metabolism Disorders | Hyperlipidemia | Diarrhea | Micro Syndrome | Congenital Hereditary Endothelial Dystrophy Type I | Intracranial Hypertension | Vitamin D Deficiency | Encephalopathy, Ethylmalonic | Stromal Corneal Dystrophy | Guanidinoacetate Methyltransferase Deficiency | Migraine | Osteochondroma | CEDNIK Syndrome | Primary Hyperoxaluria Type 1 | Angioedema, Hereditary | Achromatopsia | Paroxysmal Nocturnal Hemoglobinuria | Rash | Infectious Diarrhea | Menkes Disease | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Metatropic Dysplasia | Sclerosteosis 2 | Ameloblastic Carcinoma | Phenylketonuria II | Desbuquois Syndrome | Argininosuccinic Aciduria | Blood Protein Disorders | Lymphoma, Mantle Cell | Shock, Cardiogenic | Basan Syndrome | Idiopathic Multicentric Castleman Disease | Schnitzler Syndrome | GM2-gangliosidosis AB Variant | Hypopigmentation | KBG Syndrome | Hypohidrotic Ectodermal Dysplasia | Hemimegalencephaly | Constipation | Joubert Syndrome 2 | Spinocerebellar Ataxia Type 2 | VACTERL Association | Corneal Neovascularization | Episodic Ataxia Type 2 | Corneal Edema | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Bloom Syndrome | Sarcoma | Emery-Dreifuss Muscular Dystrophy | Pseudohypoparathyroidism Type 1A | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Pure Red Cell Aplasia | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Ophthalmoplegia | Autoimmune Polyendocrine Syndrome | Autonomic Neuropathy | NGLY1 Deficiency | Fuchs Heterochromic Iridocyclitis | Hepatitis, Autoimmune | Congenital Absence Of Vas Deferens | Tardive Dyskinesia | Adenomatoid Tumor | Narcolepsy | Hydronephrosis | Keratoconjunctivitis | Cushing Syndrome | Cryptosporidiosis | Chanarin-Dorfman Syndrome | Anti-NMDA Receptor Encephalitis | Myelitis | Keratosis, Actinic | Exfoliative Dermatitis | Turner's Syndrome | Cardiofaciocutaneous Syndrome | Otitis Media | Hermansky-Pudlak Syndrome | Neuroma | Chitayat Syndrome | Pancytopenia | Prader-Willi Syndrome | Infantile Liver Failure Syndrome 1 | Waardenburg Syndrome Type 4A | Polycythemia Vera | Asthma, Nocturnal | Hyperparathyroidism, Secondary | Ovarian Sex Cord-stromal Tumor | Pierpont Syndrome | Tuberculosis | Essential Fructosuria | Cartilage Disorders | Chronic Myeloid Leukemia | Trichothiodystrophy | Retinitis | Bacterial Meningitis | Long QT Syndrome Type 2 | Hypersensitivity Pneumonitis | Usher Syndrome Type I | Urea Cycle Disorder | Lymphomatoid Granulomatosis | Paraplegia | Coffin-Lowry Syndrome | Iron Overload | Primary Torsion Dystonia | Amenorrhea | Congenital Bilateral Absence Of Vas Deferens | Cardiomyopathy, Peripartum | Meleda Disease | Trigonocephaly | Hydrocephalus | Down Syndrome | Short-chain Acyl-CoA Dehydrogenase Deficiency | Pineoblastoma | Diabetes Gestational | Peripheral Neuropathy | Heroin Dependence | Chorea-acanthocytosis | Sulfite Oxidase Deficiency | Centronuclear Myopathy | Carey-Fineman-Ziter Syndrome | Corneal Ulcer | Charcot-Marie-Tooth Disease Axonal Type 2N | Angina Pectoris | Familial Hypertrophic Cardiomyopathy | Sclerosing Cholangitis | Infantile Spasm | Cataplexy | Dysequilibrium Syndrome | Stickler Syndrome | Endocarditis | Leber Hereditary Optic Neuropathy | Hartnup Disease | Usher Syndrome Type II | Nemaline Myopathy 10 | Loeys-Dietz Syndrome Type 4 | Marinesco-Sjogren Syndrome | Gliosarcoma | Riboflavin Transporter Deficiency Neuronopathy | Metachondromatosis | Benign Recurrent Intrahepatic Cholestasis 1 | Blau Syndrome | Lentigo | Creatine Deficiency Syndrome | Chordoma | Keratitis-ichthyosis-deafness Syndrome | Donnai-Barrow Syndrome | Bursitis | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Charcot-Marie-Tooth Disease, Type 1A | Pyruvate Kinase Deficiency | Lymphoma Lymphoblastic | Osteonecrosis | Thin Basement Membrane Disease | Blepharoconjunctivitis | Chronic Enteropathy Associated With SLCO2A1 Gene | Hypogammaglobulinemia | Spinal Muscular Atrophy Type 2 | Chondrosarcoma | Fibronectin Glomerulopathy | Choroiditis | Chondromyxoid Fibroma | Focal Dermal Hypoplasia | Hyperparathyroidism, Primary | Congenital Adrenal Hyperplasia | Smoldering Myeloma | Medulloblastoma | Asplenia | Cabezas Syndrome | Sotos Syndrome | Ureteropelvic Junction Obstruction | Graft-versus-host Disease | Chorea | Antithrombin III Deficiency | Chronic Periodontitis | Hypercholesterolemia | Tyrosinemia Type 2 | Congenital Adrenal Hyperplasia 1 | Histiocytic Sarcoma | Arthrogryposis | Porokeratosis | Trismus-pseudocamptodactyly Syndrome | Multisystemic Smooth Muscle Dysfunction Syndrome | Hepatitis, Alcoholic | Iron Deficiency Anemia | Cantu Syndrome | Neuroblastoma | Keloid | Sezary Syndrome | Acquired Partial Lipodystrophy | Persistent Hyperplastic Primary Vitreous | Dysplastic Nevus | Myasthenia | Stroke | Sialoadenitis | Dementia | Charcot-Marie-Tooth Disease Type 2D | Otosclerosis | Alcoholism | Congenital Ichthyosiform Erythroderma | Pulmonary Alveolar Microlithiasis | Pneumonia, Bacterial | Congenital Mirror Movements | Transthyretin-related Amyloidosis | Hypersomnia | Acute Generalized Exanthematous Pustulosis | Bronchitis | Osteopathia Striata With Cranial Sclerosis | Autosomal Recessive Bestrophinopathy | Dengue Hemorrhagic Fever | Psoriasis | Dermatofibrosarcoma | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Usher Syndrome Type III | Weill-Marchesani Syndrome | Hodgkin Lymphoma | Batten Disease | Polycystic Ovary Syndrome | Neurodevelopmental Disorders | Rolandic Epilepsy | L-2-Hydroxyglutaric Aciduria | Thyroid Dyshormonogenesis | Primary Sclerosing Cholangitis | Congenital Hypofibrinogenemia | Mevalonate Kinase Deficiency | Choroideremia | Spinocerebellar Ataxia Type 31 | Multiple Myeloma | Nance-Horan Syndrome | Klinefelter Syndrome | Nephrocalcinosis | Congenital Muscular Dystrophy | Methemoglobinemia | Malignant Peripheral Nerve Sheath Tumor | Hypohidrotic Ectodermal Dysplasia, X-linked | Disseminated Superficial Actinic Porokeratosis | Huntington's Disease-like 2 | Metabolic Syndrome | Gerstmann-Straussler-Scheinker Syndrome | Protein S Deficiency | McLeod Syndrome | Insulinoma | Myoclonus | Congenital Lipoid Adrenal Hyperplasia | Chronic Kidney Disease | Subcortical Band Heterotopia | Pseudohypoaldosteronism | Rhabdoid Tumor | Mastitis | Blastoma, Pleuropulmonary | Pulmonary Capillary Hemangiomatosis | Chudley-McCullough Syndrome | Diabetic Macular Edema | Persistent Fetal Circulation | Meningioma | Menetrier Disease | Hyperlipidemia, Familial Combined | Early Infantile Epileptic Encephalopathy | Cardiomyopathy, Restrictive | Oligodendroglioma | Immunoproliferative Disorders | Tylosis With Esophageal Cancer | Conjunctivitis, Allergic | Peters-plus Syndrome | Wolfram Syndrome 2 | Traboulsi Syndrome | Craniometaphyseal Dysplasia | Macrodactyly | Combined Malonic And Methylmalonic Acidemia | Ichthyosis, X-linked | Polymicrogyria | Mountain Sickness | Hypoalbuminemia | Acute Anterior Uveitis | Acrocallosal Syndrome | Oculopharyngeal Muscular Dystrophy | Familial Digital Arthropathy-brachydactyly | Optic Neuritis | Lactose Intolerance | Thyroiditis | Pilomatrix Carcinoma | Optic Neuropathy, Anterior Ischemic | Encephalopathy | Palmoplantar Keratoderma | Nicotine Addiction | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Glaucomatocyclitic Crisis | Placenta Previa | Onchocerciasis | Beckwith-Wiedemann Syndrome | Congenital Tufting Enteropathy | Generalized Epilepsy And Paroxysmal Dyskinesia | Pulmonary Vein Stenosis | Alveolar Capillary Dysplasia | Anodontia | Rhizomelic Chondrodysplasia Punctata | Primary Pigmented Nodular Adrenocortical Disease | Hyper IgE Syndrome | Canavan Disease | Takotsubo Cardiomyopathy | Presbycusis | Veno-occlusive Disease | Intestinal Tuberculosis | Retinal Vasculitis | Hyperostosis | Hepatitis | Temtamy Preaxial Brachydactyly Syndrome | Astigmatism | Hypertension, Portal | Avian Influenza | Infantile Refsum Disease | B-cell Prolymphocytic Leukemia | Situs Inversus | Charcot-Marie-Tooth Disease Type 4B1 | Familial Glucocorticoid Deficiency | Nephrotic Syndrome | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Shwachman-Bodian-Diamond Syndrome | Alopecia | Viral Meningitis | Methylmalonic Acidemia | Ligneous Conjunctivitis | Dowling-Degos Disease | Christianson Syndrome | Microtia | Alopecia Areata | Hereditary Hemorrhagic Telangiectasia Type 2 | ICF Syndrome | Echinococcosis | Cleidocranial Dysplasia | Poretti-Boltshauser Syndrome | Parkinsonism | Osteoporosis-pseudoglioma Syndrome | Skin Fragility-woolly Hair Syndrome | Meier-Gorlin Syndrome | Wolcott-Rallison Syndrome | Ebstein Anomaly | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Erythromelalgia | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Alstrom Syndrome | Fraser Syndrome | Li-Fraumeni Syndrome | Glutaric Aciduria Type 2 | Diabetic Nephropathy | Arteriovenous Malformations | Tonsillitis | IgA Deficiency | Spinocerebellar Ataxia Type 10 | Heimler Syndrome | Von Willebrand Disease | Isovaleric Acidemia | Choriocarcinoma | Pyruvate Dehydrogenase Deficiency | Charcot-Marie-Tooth Disease Type 4 | Preaxial Polydactyly | Plasma Cell Dyscrasia | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Leukodystrophies | Antenatal Bartter Syndrome Type 1 | Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia | Polymyositis | Subacute Sclerosing Panencephalitis | Retinitis Pigmentosa | Osteomyelitis | Hypophosphatasia | Progressive Familial Intrahepatic Cholestasis | Neuronal Ceroid Lipofuscinosis | Pulmonary Stenosis | Myofibrillar Myopathy | Anal Fissure | Purpura, Thrombotic Thrombocytopenic