Sick Sinus Syndrome

About the Disease
Sick Sinus Syndrome, also known as sinus node dysfunction, is related to familial sick sinus syndrome and cardiac arrhythmia, ankyrin-b-related. An important gene associated with Sick Sinus Syndrome is SCN5A (Sodium Voltage-Gated Channel Alpha Subunit 5), and among its related pathways/superpathways are Cardiac conduction and G-Beta Gamma Signaling. The drugs Nebivolol and Atenolol have been mentioned in the context of this disorder. Affiliated tissues include heart, atrioventricular node and cardiac myocytes, and related phenotypes are no effect and no effect

Common Targets
KCNJ12 | HCN4 | KCNK15 | CACNA1S | DMPK | ACADS | SHOX2 | TMPO | FGA | KCNE1 | ALMS1 | beta-Adrenoceptor (nonspecified subtype) | TTN | LMNA | MYH6 | KCNMB1 | TGFB1 | PKP4 | SCN5A | KCNJ10 | MYH7 | HFE

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