Hypodontia

About the Disease
Tooth Agenesis, also known as oligodontia, is related to tooth agenesis, selective, 1 and ectodermal dysplasia 13, hair/tooth type. An important gene associated with Tooth Agenesis is PAX9 (Paired Box 9), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Malignant pleural mesothelioma. The drugs Ibuprofen and Amoxicillin have been mentioned in the context of this disorder. Affiliated tissues include bone, bone marrow and brain, and related phenotypes are oligodontia and impaired mastication

Common Targets
EDA | MSX1 | BMP2 | DKK1 | NSD1 | DSP | COL17A1 | ANTXR1 | WNT10A | LAMA3 | RUNX2 | PAX9

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