Acute Tubular Necrosis

About the Disease
Acute Kidney Tubular Necrosis, also known as acute tubular necrosis, is related to lipoid nephrosis and acute kidney failure. An important gene associated with Acute Kidney Tubular Necrosis is MB (Myoglobin), and among its related pathways/superpathways are Metabolism of proteins and Interleukin-4 and Interleukin-13 signaling. The drugs Furosemide and Sodium Potassium Chloride Symporter Inhibitors have been mentioned in the context of this disorder. Affiliated tissues include kidney, bone marrow and bone, and related phenotypes are no effect and no effect

Common Targets
HLA-DRA | KRR1 | RIPK1

Note: If you'd like to get a target analysis report for Acute Tubular Necrosis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Acute Tubular Necrosis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Otitis Externa | Metachromatic Leukodystrophy | Diabetes Gestational | Neurocutaneous Melanocytosis | Aldosterone Synthase Deficiency | Blau Syndrome | Primary Sclerosing Cholangitis | Mixed Connective Tissue Disease | Pancytopenia | Currarino Syndrome | Glomerulonephritis, Membranous | Craniopharyngioma | Hereditary Folate Malabsorption | Tendinitis | Crouzon Syndrome With Acanthosis Nigricans | Myelitis | Thanatophoric Dysplasia Type 1 | Multiple Sclerosis, Relapsing-remitting | Vitelliform Macular Dystrophy | Aceruloplasminemia | Fuchs Dystrophy | Primary Lateral Sclerosis | Cutaneous Mastocytosis | Thalassemia, Beta | Pulmonary Alveolar Microlithiasis | Keratitis | Spinocerebellar Ataxia Type 8 | Polyarteritis Nodosa | Hypobetalipoproteinemias | Spinocerebellar Ataxia Type 17 | Gastroenteritis, Eosinophilic | Meningococcal Infections | Infectious Diarrhea | Polycystic Kidney, Autosomal Recessive | Stuve-Wiedemann Syndrome | Motor Neuron Diseases | Pseudohermaphroditism | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Dysgerminoma | Wiskott-Aldrich Syndrome | Polyradiculopathy | Barrett Esophagus | Pseudomyxoma Peritonei | Tyrosinemia Type 1 | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Spinocerebellar Ataxia Type 15 | Marshall-Smith Syndrome | Methylmalonic Aciduria And Homocystinuria, CblC Type | Diabetic Encephalopathy | Chronic Kidney Disease | Alpha-thalassemia Myelodysplasia Syndrome | Aicardi-Goutieres Syndrome | Bloom Syndrome | Chediak-Higashi Syndrome | Familial Male-limited Precocious Puberty | Enhanced S-cone Syndrome | Liver Diseases | Noonan Syndrome-like Disorder With Loose Anagen Hair | Pulmonary Tuberculosis | Pelvic Inflammatory Disease | Overactive Bladder | Pituitary Stalk Interruption Syndrome | Spinocerebellar Ataxia Type 5 | Bicuspid Aortic Valve | Reye Syndrome | Glycogen Storage Disease Type 1b | Urticaria | Congenital Hereditary Endothelial Dystrophy Type II | Melanocytic Nevus | Sialidosis | Geleophysic Dysplasia | Goiter | Pulmonary Capillary Hemangiomatosis | Jaundice, Obstructive | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Macrophagic Myofasciitis | Syndactyly | Parkinsonism | Hyperparathyroidism | Gingivitis | Left Ventricular Noncompaction | Heroin Dependence | Antithrombin III Deficiency | Infertility, Male | Heart Block | Mevalonate Kinase Deficiency | Pseudohypoparathyroidism Type 2 | Ellis-Van Creveld Syndrome | Congenital Stationary Night Blindness | Gout | Erythropoietic Protoporphyria | Ichthyosis | Dubin-Johnson Syndrome | Neurofibromatosis Type 2 | Poirier-Bienvenu Neurodevelopmental Syndrome | Sorsby Fundus Dystrophy | Pre-eclampsia | Neurodevelopmental Disorders | Sarcoidosis | Sick Sinus Syndrome | Tangier Disease | Spinocerebellar Ataxia Type 12 | Hypertension, Renovascular | Cardiomyopathy, Restrictive | Recurrent Respiratory Papillomatosis | Optic Neuritis | Congenital Disorders Of Glycosylation | Osteopetrosis | Genee-Wiedemann Syndrome | Agnathia-Otocephaly Complex | Dysthymia | Endometriosis | Hypertension | Cushing Syndrome | Waardenburg Syndrome Type 2E | Hypertriglyceridemia | Chudley-McCullough Syndrome | Granular Corneal Dystrophy | Waardenburg Syndrome Type 4A | Non-Hodgkin Lymphoma | Microcephaly | Rhabdomyosarcoma, Alveolar | Presbycusis | Cataplexy | Amenorrhea | Coma | Glutaric Aciduria Type 2 | Vaginitis | Congenital Fiber-type Disproportion Myopathy | Congenital Myopathy | 3-methylglutaconic Aciduria Type IV | Colitis, Microscopic | Tyrosinemia Type 2 | Krabbe Disease | Desmosterolosis | Hypotension, Orthostatic | Spondyloperipheral Dysplasia | Pericarditis | Epithelial-myoepithelial Carcinoma | Thromboembolism | Incontinentia Pigmenti | Cluster Headache | FG Syndrome | Niemann-Pick Disease | Fucosidosis | Early Infantile Epileptic Encephalopathy | Joubert Syndrome | Nephrocalcinosis | Riboflavin Transporter Deficiency Neuronopathy | Pontocerebellar Hypoplasia Type 7 | Fibrillation, Atrial | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Coffin-Lowry Syndrome | Thyroiditis | Spinocerebellar Ataxia Type 20 | Dyslipidemia | Anterior Segment Dysgenesis | Retinal Coloboma | Charcot-Marie-Tooth Disease Type 2D | Poretti-Boltshauser Syndrome | Carcinoma, Merkel Cell | Hypertelorism | Uremic Pruritus | AIDS | Acrodermatitis | Uveitis | Dental Caries | Hemangioendothelioma | Cholestasis, Intrahepatic | Sialidosis Type I | Hyperlipidemia | Glomerulonephritis, Membranoproliferative | Costello Syndrome | Trichotillomania | Leukemia-lymphoma, Adult T-cell | Oculodentodigital Dysplasia | Apraxia | Dysplastic Nevus | Thyroid Dysgenesis | Plasmacytoma | D-2-Hydroxyglutaric Aciduria | Enlarged Vestibular Aqueduct | Long-chain 3-hydroxyacyl-coenzyme A Dehydrogenase Deficiency | Angioimmunoblastic T-cell Lymphoma | Obsessive-compulsive Disorder | Usher Syndrome Type I | Cutaneous Angiosarcoma | Camurati-Engelmann Disease | Charcot-Marie-Tooth Disease Type 2T | Diabetes Type 2 | Epilepsy | Gallstones | Seminoma | Synpolydactyly | Personality Disorders | Coronary Restenosis | Diarrhea | Hyperprolactinemia | Spinocerebellar Ataxia Type 7 | Hepatic Steatosis | Charcot-Marie-Tooth Disease Type 4 | Choroiditis | Oral Lichen Planus | Sponastrime Dysplasia | Motion Sickness | Pneumonia, Viral | Congenital Lipoid Adrenal Hyperplasia | Bone Giant Cell Tumor | Erythema Nodosum | Adrenal Insufficiency | Keratosis, Seborrheic | Lymphoma, AIDS-related | Hypercalciuria | Adenosine Deaminase 2 Deficiency | Fraser Syndrome | Chromosome 17q21.31 Deletion Syndrome | Cyst | Cutis Laxa | Renal-hepatic-pancreatic Dysplasia | Fragile X Syndrome | HELLP Syndrome | Spinocerebellar Ataxia Type 28 | Fahr Disease | Bursitis | Benign Familial Neonatal Convulsions | Canavan Disease | Hypodontia | Spinocerebellar Ataxia Type 23 | Vitamin D Deficiency | Seizures-scoliosis-macrocephaly Syndrome | Pyruvate Carboxylase Deficiency Disease | Hyperandrogenemia | Primary Cutaneous Amyloidosis | Arthritis, Gouty | Sengers Syndrome | Kaposi Sarcoma | Charcot-Marie-Tooth Disease Type 4D | Lattice Corneal Dystrophy Type 1 | Toxic Epidermal Necrolysis | Cousin Syndrome | Arthrogryposis | Hyperostosis | Coffin-Siris Syndrome | Deafness, Dystonia, And Cerebral Hypomyelination | Crohn's Disease | Myasthenia | Myopia | Occipital Neuralgia | Goldenhar Syndrome | Hereditary Multiple Exostoses | Autism | Diabetic Neuropathy | Multiple Epiphyseal Dysplasia | Richter's Syndrome | Ligneous Conjunctivitis | Cancer, Skin | Fibrodysplasia Ossificans Progressiva | Pyruvate Dehydrogenase Deficiency | Polycystic Kidney, Autosomal Dominant | Thanatophoric Dysplasia | Hypoplastic Left Heart Syndrome | Ovarian Sex Cord-stromal Tumor | Smith-Magenis Syndrome | Menetrier Disease | Anthrax | Pterygium | Hereditary Mixed Polyposis Syndrome | Ameloblastic Carcinoma | Congenital Dyserythropoietic Anemia Type 1 | Hepatopulmonary Syndrome | Chordoma | Beckwith-Wiedemann Syndrome | Angioedema, Hereditary | Retinoschisis | ADNP Syndrome | Maple Syrup Urine Disease | Brooke-Spiegler Syndrome | Partington Syndrome | Epidermolytic Ichthyosis, Annular | Distal Myopathy 2 | Retinal Dystrophy, Early-onset Severe | Chronic Thromboembolic Pulmonary Hypertension | Tuberculous Meningitis | HUPRA Syndrome | Chloridorrhea, Congenital | Nemaline Myopathy 10 | Esophageal Carcinoma | Eosinophilia | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | PHARC Syndrome | Acute Coronary Syndrome | Glycogen Storage Disease Type 0 | Ollier Disease | Myotonia | Acute Tubular Necrosis | 3-methylglutaconic Aciduria Type I | Bardet-Biedl Syndrome | Spondylocostal Dysostosis | Dysequilibrium Syndrome | Fundus Albipunctatus | Epithelioid Hemangioma | Early Infantile Epileptic Encephalopathy 4 | Lymphoproliferative Disorders | Fetal Alcohol Syndrome | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Vascular Calcification | Nephroblastoma | Osteopathia Striata With Cranial Sclerosis | Monilethrix | Cyclic Vomiting Syndrome | Spinocerebellar Ataxia Type 14 | Acanthosis Nigricans | Corneal Dystrophy And Perceptive Deafness | Angiodysplasia | Epilepsy, Generalized | Triple A Syndrome | Low Phospholipid Associated Cholelithiasis | Hyperacusis | Mucolipidosis Type II | Neovascular Glaucoma | Transient Bullous Dermolysis Of The Newborn | Pelizaeus-Merzbacher Disease | Dupuytren Disease | Extramammary Paget's Disease | Fanconi Anemia | Autosomal Recessive Spastic Paraplegia Type 54 | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Acromicric Dysplasia | Hyperkalemic Periodic Paralysis | Menkes Disease | Leigh Syndrome | Echinococcosis | Tumoral Calcinosis | Charcot-Marie-Tooth Disease, Type 1A | Camptocormia | Localized Scleroderma | Mohr-Tranebjaerg Syndrome | Trismus-pseudocamptodactyly Syndrome | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Skin Papilloma | Craniofacial Dysostosis | Orthostatic Intolerance | Atelosteogenesis Type 2 | Anosmia, Congenital | Aphasia | Spinocerebellar Ataxia Type 38 | Hypospadias | Wilson's Disease | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | CDKL5 Deficiency Disorder | Renal Tubular Acidosis | Treacher Collins Syndrome | Amyotrophic Lateral Sclerosis, Juvenile | Dent Disease | Hepatitis B, Chronic | Cryopyrin-associated Periodic Syndromes | Osteochondrosis | Shprintzen-Goldberg Syndrome | Hennekam Lymphangiectasia-lymphedema Syndrome | Dermatitis | Thyroid Dyshormonogenesis | Klippel-Feil Syndrome | Spondyloarthritis | Demyelinating Diseases | Schaaf-Yang Syndrome | Senior-Loken Syndrome | Oculocutaneous Albinism Type 2 | Atopy | Hypoalbuminemia | Charcot-Marie-Tooth Disease | Paroxysmal Kinesigenic Dyskinesia | Hypervalinemia | Sarcosinemia | Primary Familial Brain Calcification | Progressive Familial Intrahepatic Cholestasis Type 2 | Methemoglobinemia | Weill-Marchesani Syndrome | Craniofrontonasal Syndrome | Infantile Refsum Disease | Pierson Syndrome | Citrullinemia | Trachoma | Autosomal Recessive Congenital Ichthyosis | Auriculocondylar Syndrome | Multiple Sclerosis, Secondary Progressive | Eosinophilic Asthma | Neuromyelitis Optica | Loeys-Dietz Syndrome | Klinefelter Syndrome | Tyrosine Hydroxylase Deficiency | Takotsubo Cardiomyopathy | Ichthyosis Bullosa Of Siemens | Osteogenesis Imperfecta Type II | Choroideremia | Xeroderma Pigmentosum Variant Type | Arthritis, Reactive | Asperger Syndrome | Holt-Oram Syndrome | Muscular Dystrophy | Familial Glucocorticoid Deficiency