Early Infantile Epileptic Encephalopathy

About the Disease
Early Infantile Epileptic Encephalopathy, also known as early infantile epileptic encephalopathy with suppression bursts, is related to developmental and epileptic encephalopathy 14 and developmental and epileptic encephalopathy 1. An important gene associated with Early Infantile Epileptic Encephalopathy is SLC25A22 (Solute Carrier Family 25 Member 22), and among its related pathways/superpathways are Transmission across Chemical Synapses and G-Beta Gamma Signaling. Affiliated tissues include brain, cortex and eye, and related phenotypes are intellectual disability and global developmental delay

Common Targets
GOT2 | CACNA2D2 | AARS1 | RHOBTB2 | SLC25A22 | GRIN1 | DENND5A | SLC19A3 | GNAO1 | UBA5 | PIGK | KCNQ3 | CDKL5 | GABA(A) receptor | NFU1 | PARS2 | PIGQ | PCDH19 | PIGA | WWOX | SCN8A | GRIN2D | PRRT2 | ARV1 | ARX | ARHGEF9 | TBC1D24 | CARS2 | RS1 | NECAP1 | CELSR3 | SZT2 | SLC13A5 | SLC12A5 | SPTAN1 | GRIN2A | SCO1 | SEPSECS | GABRA1 | SLC25A12 | QARS1 | NSF | HRH1 | SCN1A | ITPA | KCNT1 | CACNA1A | HID1 | BRAT1 | PACS2 | GABRA2 | SCN1B | NGLY1 | EPRS1 | HCN1 | ETHE1 | GRIN2B | PLCB1 | ACTL6B | DOCK7 | ABAT | KCNA2 | FRRS1L | STXBP1 | KCNQ2 | KCNB1 | SCN2A | AP3B2 | PNPO | DNM1

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Other Diseases

Chronic Enteropathy Associated With SLCO2A1 Gene | Syncope | Agammaglobulinemia | Synpolydactyly | IMAGe Syndrome | Choriocarcinoma | Blepharo-cheilo-odontic Syndrome | Colon Adenoma | Hereditary Hemorrhagic Telangiectasia | Chromosome 8q21.11 Deletion Syndrome | Tyrosinemia Type 2 | Mycosis Fungoides | Schizencephaly | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Hemophilia | Meningococcal Meningitis | Chorea-acanthocytosis | Narcolepsy | Muckle-Wells Syndrome | Crouzon Syndrome With Acanthosis Nigricans | Arthritis, Psoriatic | LEOPARD Syndrome | Panuveitis | Bronchiolitis | Cancer, Skin | Cohen Syndrome | Vitiligo | Glutaric Aciduria Type 3 | T-cell Leukemia | Gastric Atrophy | Myoclonus-dystonia Syndrome | Peripheral T-cell Lymphoma | Chronic Neutrophilic Leukemia | Leri Pleonosteosis | Neurodermatitis | Chondromyxoid Fibroma | Mucolipidosis Type II | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Idiopathic Multicentric Castleman Disease | Benign Familial Pemphigus | Fragile X Syndrome | Treacher Collins Syndrome | Congenital Hereditary Endothelial Dystrophy Type I | Leukoencephalopathy, Progressive Multifocal | Hyperostosis | Bardet-Biedl Syndrome | Fucosidosis | X-linked Acrogigantism | Goldenhar Syndrome | McCune-Albright Syndrome | Krabbe Disease | Oculocutaneous Albinism | Alpers Syndrome | Spondyloepiphyseal Dysplasia Tarda, X-linked | Fibrodysplasia Ossificans Progressiva | Frank-ter Haar Syndrome | Amelogenesis Imperfecta | Cardiac Sarcoidosis | Chorioretinitis | Rosacea | Unverricht-Lundborg Syndrome | Cenani-Lenz Syndactyly Syndrome | Autoimmune Disease | Glutaric Aciduria Type 1 | Dysferlinopathy | Eczema | Multiple Myeloma | Cutaneous Angiosarcoma | Arteriosclerosis | Primary Pigmented Nodular Adrenocortical Disease | Cancer, Breast | Colorectal Adenoma | Sclerosteosis 2 | Gastroenteritis, Eosinophilic | Colitis, Microscopic | Enlarged Vestibular Aqueduct | Spinocerebellar Ataxia Type 3 | Blepharitis | Pseudomyxoma 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Agnathia-Otocephaly Complex | Dubin-Johnson Syndrome | Familial Hypertrophic Cardiomyopathy | Hemoglobinopathies | Pitt-Hopkins Syndrome | Adenoid Cystic Carcinoma | Kallmann Syndrome | Angina Pectoris | T-cell Prolymphocytic Leukemia | Warsaw Breakage Syndrome | TARP Syndrome | Nicotine Addiction | Triple A Syndrome | Hypereosinophilic Syndrome | Pyelonephritis | Non-epidermolytic Palmoplantar Keratoderma | Polycythemia Vera | Essential Fructosuria | Cancer, Bladder | Thrombophilia | Congenital Absence Of Vas Deferens | Inflammatory Myopathy | Keratitis | Odonto-onycho-dermal Dysplasia | Hereditary Sensory And Autonomic Neuropathy | Nephrotic Syndrome Type 1 | Atelosteogenesis Type 1 | Hyperinsulinism-hyperammonemia Syndrome | Brooke-Spiegler Syndrome | Hypokalemic Periodic Paralysis | Cabezas Syndrome | Malaria, Cerebral | Hemimegalencephaly | Camurati-Engelmann Disease | Amenorrhea | Hepatitis B, Chronic | Alazami Syndrome | Tinea Versicolor | Muscular Dystrophy | Stargardt Disease | Periventricular Nodular Heterotopia | Pneumonia, Viral | Coronary Restenosis | Cartilage Disorders | Anorectal Fistula | Mevalonate Kinase Deficiency | Von Willebrand Disease | Hypermetropia | Retinal Coloboma | Sarcoma, Endometrial Stromal | Immunoproliferative Disorders | Congenital Hypofibrinogenemia | Ulcerative Colitis | Intestinal Hypomagnesemia 1 | Headache | Dysgerminoma | ICF Syndrome | Chiari Malformation Type I | Hypospadias | Combined Deficiency Of Factor V And Factor VIII | Hyperuricemic Nephropathy, Familial Juvenile | Thyroid Dyshormonogenesis | Keratoacanthoma | Birk-Barel Syndrome | Fatty Aldehyde Dehydrogenase Deficiency | Porphyria Cutanea Tarda | B-cell Prolymphocytic Leukemia | Twin-to-twin Transfusion Syndrome | Nasodigitoacoustic Syndrome | Teratozoospermia | DICER1 Syndrome | Majeed Syndrome | Intestinal Pseudo-obstruction | Trichomegaly | Adrenoleukodystrophy, X-linked | Spasticity | Focal Facial Dermal Dysplasia | Duchenne Muscular Dystrophy | Cerebral Amyloid Angiopathy | Keratopathy | Nutrition Disorders | Pelvic Inflammatory Disease | Mucolipidosis | Methylmalonic Acidemia | Crisponi Syndrome | Priapism | Neutropenia | Paraganglioma | Neurocysticercosis | Charcot-Marie-Tooth Disease, Type 2C | Hereditary Folate Malabsorption | X-linked Sideroblastic Anemia | Prolidase Deficiency | Encephalitis | Iron Metabolism Disorders | Adenoma, Pleomorphic | Smith-Kingsmore Syndrome | Echinococcosis | Acute Kidney Injury | Aplastic Anemia | Dengue Hemorrhagic Fever | Neuromyelitis Optica | Familial Cerebral Amyloid Angiopathy | Renal Hypomagnesemia 3 | Disseminated Intravascular Coagulation | Hernia, Inguinal | REM Sleep Behavior Disorder | Niemann-Pick Disease, Type B | Neuroectodermal Tumors, Primitive | Necrotizing Autoimmune Myopathy | Pleural Tuberculosis | Polycystic Ovary Syndrome | Pregnancy, Ectopic | Myocardial Infarction | Blue Rubber Bleb Nevus Syndrome | Intestinal Obstruction | Craniopharyngioma | Cancer, Lung | Peeling Skin Syndrome Type B | Spinal Cord Diseases | Ureteropelvic Junction Obstruction | Sleep Apnea, Central | Hyperacusis | Aicardi-Goutieres Syndrome | Primary Hyperoxaluria Type 3 | Glycogen Storage Disease Type 5 | Exocrine Pancreatic Insufficiency | Borderline Personality Disorder | Amblyopia | Coffin-Lowry Syndrome | Congenital Ichthyosiform Erythroderma | Erythromelalgia | Early Infantile Epileptic Encephalopathy | Thyrotoxic Periodic Paralysis | Myelodysplasia | Sarcosinemia | Dermatofibrosarcoma | Lipid Storage Myopathy | Primary Ovarian Insufficiency | Basan Syndrome | Charcot-Marie-Tooth Disease Type 2T | Osteoporosis | Sleep Apnea | Primary Aldosteronism | Cryoglobulinemia | Autoimmune Polyendocrine Syndrome | Macrophagic Myofasciitis | Astrocytoma, Anaplastic | Keratoconus | B-cell Chronic Lymphocytic Leukemia | Sialoadenitis | Autosomal Recessive Spastic Paraplegia Type 35 | Urolithiasis | Fowler's Syndrome | Mood Disorder | Craniolenticulosutural Dysplasia | High Molecular Weight Kininogen Deficiency | Erdheim-Chester Disease | GM2-gangliosidosis AB Variant | Contact Dermatitis | Meningioma | Acute Tubular Necrosis | Chorea | Hypersensitivity Pneumonitis | Botulism | Histiocytosis | Spinocerebellar Ataxia Type 12 | Progressive Familial Intrahepatic Cholestasis Type 1 | GATA2 Deficiency | Leigh Syndrome | Vulvovaginitis | Choroiditis | Ectodermal Dysplasia | Microcephalic Osteodysplastic Primordial Dwarfism, Type II | Follicular Dendritic Cell Sarcoma | Mitochondrial DNA Depletion Syndrome | Congenital Disorders Of Glycosylation Type II | Hypoalbuminemia | Basal Ganglia Disease, Biotin-responsive | Chronic Myeloid Leukemia | Acute Chest Syndrome | Neuroleptic Malignant Syndrome | Vitamin D Deficiency | Tyrosinemia Type 1 | Poikiloderma With Neutropenia | Skin Fragility-woolly Hair Syndrome | Panic Disorder | Malonyl-CoA Decarboxylase Deficiency | Conjunctivitis | Hypercholesterolemia, Familial | Spinocerebellar Ataxia Type 13 | Glomerulonephritis, 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Endometriosis | Diabetic Nephropathy | Postpoliomyelitis Syndrome | Craniosynostosis | Cervical Dystonia | Aldosterone Deficiency | Cholecystitis | Neonatal Progeroid Syndrome | Acute Coronary Syndrome | Restless Legs Syndrome