Skin Cancer

About the Disease
Skin Carcinoma, also known as skin cancer, is related to xeroderma pigmentosum, complementation group f and rothmund-thomson syndrome, type 2. An important gene associated with Skin Carcinoma is TP53 (Tumor Protein P53), and among its related pathways/superpathways are Homology Directed Repair and Transcription-Coupled Nucleotide Excision Repair (TC-NER). The drugs Petrolatum and Etanercept have been mentioned in the context of this disorder. Affiliated tissues include skin, tissues of the skin and lymph node, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Common Targets
Vascular endothelial growth factors (VEGF) (nonspecified subtype) | STPG1 | G6647 | ABL1 | TMC8 | CCR10 | ACTA2 | IL1B | Prostaglandin EP Receptor (nonspecified subtype) | CDC42BPB | G7015 | G3569 | MC1R | AKAP12 | G2335 | PRKACG | CSK | Tyrosine-Protein Kinases Src (nonspecified subtype) | HDAC2 | LRRK2 | Melanin | L-type voltage-dependent calcium channel complex | CCND2 | NR3C2 | HRAS | NRAS | NF-kappaB (NFkB) | G5133 | IL2RA | XRCC2 | SLC7A5 | AXL | KIT | PADI6 | G7099 | CSF1R | TMC6 | AQP3 | ACE | LOC102724428 | G5728 | MUTYH | TYR | KRT5 | KEAP1 | BCR | EVC | LOC101928135 | LOC102724520 | G23411 | IL-5 receptor | LINC-PINT | CDKN2B-AS1 | HDAC3 | G1029 | ABCA1 | PDGFRB | CD40 | IRF4 | ANGPT2 | PBK | HDAC1 | SMURF1 | Reverse transcriptase (Telomerase) | TGFBR1 | LILRB2 | PTGS1 | CSMD1 | TGM3 | PRF1 | XDH | Anandamide membrane transporter (AMT) | Interferon (nonspecified subtype) | G7157 | G3630 | NR1H4 | G836 | FAAH | RXRA | Leukotriene B4 receptor (LTB4-R) (nonspecified subtype) | Tubulin | ABCC8 | CLPTM1L | Transcriptional Enhancer Factor (TEAD) (nonspecified subype) | SIK2 | PRKCB | L-Type calcium channel (nonspecified subtype) | IL1A | SLC45A2 | CDC42BPA | CTLA4 | G5743 | SIK1 | LRP2 | VDR | LOC105374875 | NT5E | RXRG | PDGFRA | IL10 | MGMT | TOP2A | MTHFR | GRHL3-AS1 | TFPI2 | SIK3 | KDR | LOC101927668 | NCKAP5 | APC | XRCC1 | TNFRSF9 | G1956 | TLR7 | Monoamine oxidase (MAO) (nonspecified subtype) | G10413 | Superoxide dismutase (SOD) (nonspecified subtype) | RGS22 | IL2RB | G3845

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