Primrose Syndrome

About the Disease
Primrose Syndrome, also known as intellectual disability-cataracts-calcified pinnae-myopathy syndrome, is related to chromosome 3q13.31 deletion syndrome and alacrima, achalasia, and mental retardation syndrome. An important gene associated with Primrose Syndrome is ZBTB20 (Zinc Finger And BTB Domain Containing 20). Affiliated tissues include eye, brain and bone, and related phenotypes are intellectual disability and scoliosis

Common Targets
ZBTB20

Note: If you'd like to get a target analysis report for Primrose Syndrome, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Primrose Syndrome at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Genee-Wiedemann Syndrome | Lichen Sclerosus | Long QT Syndrome Type 2 | Congenital Torticollis | Epidermodysplasia Verruciformis | Partington Syndrome | Citrullinemia | Communication Disorders | Guillain-Barre Syndrome | Nevus | Glycogen Storage Disease Type 1b | Tangier Disease | Infantile Spasm | Sulfite Oxidase Deficiency | Charcot-Marie-Tooth Disease Type 4D | Persistent Hyperplastic Primary Vitreous | Malnutrition | Malonyl-CoA Decarboxylase Deficiency | Salla Disease | Otitis Media | C3 Glomerulonephritis | Conjunctivitis, Allergic | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Split Hand-foot Malformation | Chorioretinitis | DNA Ligase IV Deficiency | Pneumococcal Meningitis | Facioscapulohumeral Muscular Dystrophy Type 2 | Oculocutaneous Albinism Type 2 | Congenital Heart Block | Cancer, Kidney | Jacobsen Syndrome | Scoliosis | Early Infantile Epileptic Encephalopathy 1 | Barrett Esophagus | Borjeson-Forssman-Lehmann Syndrome | Iron Overload | Encephalopathy, Hepatic | Meningococcal Meningitis | Meningeal Melanocytoma | Lentigo | Blepharo-cheilo-odontic Syndrome | Coenzyme Q10 Deficiency | Iron Deficiency Anemia | Neurodermatitis | Cornelia De Lange Syndrome | Anorexia Nervosa | Adrenoleukodystrophy, X-linked | Van Der Knaap Disease | Hypertriglyceridemia | Hyperphenylalaninemia | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Netherton Syndrome | Alpha-1 Antitrypsin Deficiency | Carpal Tunnel Syndrome | Cysticercosis | Chondrodysplasia Punctata | Persistent Truncus Arteriosus | Hereditary Inclusion Body Myopathy | Focal Facial Dermal Dysplasia | Pyruvate Kinase Deficiency | Hypokalemia | NGLY1 Deficiency | Hydrocephalus | Fetal And Neonatal Alloimmune Thrombocytopenia | Primary Carnitine Deficiency | Adenoid Cystic Carcinoma | Bicuspid Aortic Valve | Spondyloarthritis | Cocaine-Related Disorders | Prostatitis | Bardet-Biedl Syndrome | X-linked Acrogigantism | IgA Deficiency | CREST Syndrome | Primary Biliary Cholangitis | Waardenburg Syndrome Type 4 | Camptocormia | Mixed Connective Tissue Disease | Hodgkin Lymphoma | Diabetes Insipidus | Extramammary Paget's Disease | Cone Dystrophy | Cluster Headache | Cardiofaciocutaneous Syndrome | Neuromyotonia | Meier-Gorlin Syndrome | Keratitis | Spitz Nevus | Metanephric Adenoma | Thanatophoric Dysplasia | Parkinson Disease 6, Autosomal Recessive Early-onset | Primary Erythromelalgia | Viral Meningitis | Usher Syndrome Type IIC | Omenn Syndrome | Pre-eclampsia | Chronic Leukemia | Autoimmune Polyendocrine Syndrome | B-cell Chronic Lymphocytic Leukemia | Myotonia | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Xeroderma Pigmentosum | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Antithrombin III Deficiency | Pseudo-pseudohypoparathyroidism | Postpartum Depression | CEDNIK Syndrome | Pneumoconiosis | Huntington's Disease | Hemolytic Anemia | Pycnodysostosis | Glycogen Storage Disease Type 6 | T-cell Leukemia | Methemoglobinemia Type IV | Myeloid Leukemia | Erectile Dysfunction | Kaposiform Hemangioendothelioma | Sensory Neuropathy | Hemolytic Uremic Syndrome | Bartsocas-Papas Syndrome | Myoclonic Epilepsy With Ragged Red Fibers | Binge Eating Disorder | 3-methylglutaconic Aciduria Type I | Pulmonary Veno-occlusive Disease | Acromegaly | Polycystic Kidney, Autosomal Recessive | Fibrodysplasia Ossificans Progressiva | Keloid | Meniere's Disease | Alzheimer Disease, Late Onset | Gastroenteritis, Eosinophilic | Tyrosinemia Type 1 | Cerebrotendinous Xanthomatosis | Inflammatory Joint Disease | Premenstrual Syndrome | Neuromyelitis Optica | Mast Cell Leukemia | Familial Retinal Arterial Macroaneurysm | Leigh Syndrome | Budd-Chiari Syndrome | Muscle Wasting | Canavan Disease | Tyrosinemia Type 2 | Exfoliative Dermatitis | Uveitis, Anterior | Pneumothorax | Cholangitis | Trichorhinophalangeal Syndrome | Benign Hereditary Chorea | Posterior Polar Cataract | Reflex Epilepsy | Charcot-Marie-Tooth Disease Type 4B1 | Mycosis Fungoides | Neurofibromatosis-Noonan Syndrome | Corneal Dystrophy | Fowler's Syndrome | Turner's Syndrome | Vaginitis | Lactose Intolerance | Pathological Gambling | Leukoplakia, Oral | Polyradiculopathy | Guttate Psoriasis | Cutaneous Mastocytosis | Portal Vein Thrombosis | Metatropic Dysplasia | Sarcoma | Infectious Diarrhea | Otitis Externa | Myelomeningocele | Leukoencephalopathy, Progressive Multifocal | Chordoma | Tyrosine Hydroxylase Deficiency | Larsen Syndrome | Varicocele | Optic Neuritis | Hypoplastic Left Heart Syndrome | Chronic Periodontitis | Renal Hypomagnesemia 3 | Neuroectodermal Tumors, Primitive | Schizencephaly | Bronchiectasis | Gingivitis | Primary Pigmented Nodular Adrenocortical Disease | Wolfram Syndrome | Ligneous Conjunctivitis | Glutaric Aciduria Type 1 | Thrombasthenia | Dermatofibrosarcoma | Asplenia | Endometriosis | Hyperparathyroidism-jaw Tumor Syndrome | Epidermolytic Ichthyosis, Annular | Holoprosencephaly | Epidermolysis Bullosa Dystrophica | Congenital Myopathy | Congenital Dyserythropoietic Anemia | Polycystic Ovary Syndrome | Pleural Tuberculosis | Gardner Syndrome | Frank-ter Haar Syndrome | Hyperparathyroidism, Primary | Pontocerebellar Hypoplasia Type 2 | Arterial Tortuosity Syndrome | Nephropathy | Lysosomal Acid Lipase Deficiency | Fabry's Disease | Maple Syrup Urine Disease | Glioblastoma | Apert Syndrome | Rash | Erdheim-Chester Disease | Postpoliomyelitis Syndrome | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Epidermolysis Bullosa | Megaloblastic Anemia | Glaucoma, Congenital | Congenital Hereditary Endothelial Dystrophy Type I | Gynecomastia | Blau Syndrome | Hepatic Veno-occlusive Disease | Congenital Lipoid Adrenal Hyperplasia | Osteopathia Striata With Cranial Sclerosis | Nail-Patella Syndrome | Rhabdomyosarcoma, Alveolar | Lateral Meningocele Syndrome | Onchocerciasis | Hereditary Coproporphyria | Schwartz-Jampel-Aberfeld Syndrome | Acute Tubular Necrosis | Juvenile Myoclonic Epilepsy | Hypoalbuminemia | Ophthalmia, Sympathetic | Neutropenia | Autism | Melanoma, Malignant | Jaundice, Obstructive | Saethre-Chotzen Syndrome | Sick Sinus Syndrome 1 | Progressive Myoclonic Epilepsy | Chronic Beryllium Disease | Disseminated Intravascular Coagulation | Birk-Barel Syndrome | Megalencephaly | Hyperuricemic Nephropathy, Familial Juvenile | Chronic Thromboembolic Pulmonary Hypertension | Myofibrillar Myopathy | Astigmatism | Stomatitis | Richter's Syndrome | Spina Bifida | Synpolydactyly | Skin Fragility-woolly Hair Syndrome | Thyroid Dyshormonogenesis | Bladder Exstrophy | Dengue Shock Syndrome | Pyelonephritis | Methemoglobinemia | Raine Syndrome | Cancer, Prostate | Colitis, Collagenous | Pseudohypoparathyroidism Type 2 | Basan Syndrome | Mitochondrial DNA Depletion Syndrome 13 | Charcot-Marie-Tooth Disease Type 4 | Connective Tissue Disorders | Leiomyosarcoma | Jawad Syndrome | Gout | Charcot-Marie-Tooth Disease Type 2D | Colon Adenoma | Temtamy Preaxial Brachydactyly Syndrome | AIDS Dementia Complex | Juvenile Polyposis | Multiple Sclerosis, Primary Progressive | Pyruvate Carboxylase Deficiency Disease | Blepharitis | Corneal Neovascularization | Episodic Ataxia | Hyperuricemia | 3-methylcrotonyl-CoA Carboxylase Deficiency | Hereditary Multiple Exostoses | Renal Dysplasia | Corneal Edema | Juvenile Hyaline Fibromatosis | Schistosomiasis | Osteosarcoma | Aldosterone Deficiency | Xeroderma Pigmentosum Variant Type | Hepatitis A | Poretti-Boltshauser Syndrome | Gray Platelet Syndrome | Non-Langerhans Cell Histiocytosis | Osteoglophonic Dysplasia | Dermatitis Herpetiformis | Schizoaffective Disorder | Adenoma, Villous | DiGeorge Syndrome | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Still Disease | Chronic Myelomonocytic Leukemia | Ophthalmoplegia | Ectopia Lentis, Isolated, Autosomal Recessive | Heavy Chain Disease | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Hypogonadism | Myoclonus-dystonia Syndrome | Paracoccidioidomycosis | Transcobalamin Deficiency | Distal Myopathy | Oculocutaneous Albinism Type 4 | Mitochondrial Encephalomyopathy | Ellis-Van Creveld Syndrome | Optic Nerve Hypoplasia, Bilateral | Stuttering | Carcinoid Tumor | Spondyloperipheral Dysplasia | Cutaneous T-cell Lymphoma | Hypercholesterolemia | Epidermolytic Hyperkeratosis | Lipodystrophy | Heart Failure | Methylmalonic Aciduria And Homocystinuria, CblC Type | Congenital Absence Of Vas Deferens | Glycogen Storage Disease Type 3 | Nestor-Guillermo Progeria Syndrome | Bartter Syndrome | Phenylketonuria | Desbuquois Syndrome | Hyperhomocysteinemia | Early Infantile Epileptic Encephalopathy 13 | Constipation | Bulimia Nervosa | Granular Corneal Dystrophy | Contact Dermatitis | Thrombocytopenia | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Impetigo | Bruck Syndrome | Urea Cycle Disorder | Porphyria Cutanea Tarda | Lissencephaly 2 | Pituitary Stalk Interruption Syndrome | Hermansky-Pudlak Syndrome | Papilloma | Keratocystic Odontogenic Tumor | Spinocerebellar Ataxia Type 14 | Joubert Syndrome 2 | Whipple's Disease | Succinic Semialdehyde Dehydrogenase Deficiency | Interstitial Lung Diseases | Vascular Calcification | Colitis, Microscopic | Purpura, Thrombotic Thrombocytopenic | Eclampsia | LMNA-related Congenital Muscular Dystrophy | Trichothiodystrophy | Familial Male-limited Precocious Puberty | Atopic Dermatitis | Pyoderma Gangrenosum | Miyoshi Myopathy | 3-hydroxy-3-methylglutaric Aciduria | ACTH-independent Macronodular Adrenal Hyperplasia | Hereditary Sensory Neuropathy Type 1 | Hemophilia | Aplastic Anemia | HANAC Syndrome | Arthritis, Psoriatic | Currarino Syndrome | Heroin Dependence | HUPRA Syndrome | Protein S Deficiency | Multifocal Motor Neuropathy | Porphyria, Acute Intermittent | Takenouchi-Kosaki Syndrome | Microcephaly | Congenital Nephrotic Syndrome | Hypospadias | Atopy | Glaucoma | Paroxysmal Nocturnal Hemoglobinuria | Plasma Cell Leukemia | Kashin-Beck Disease | Schistosomiasis Mansoni | Encephalopathy | Charcot-Marie-Tooth Disease Type 3 | Sorsby Fundus Dystrophy | Hemosiderosis | Amblyopia | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Esophagitis | Acute Leukemia | Craniolenticulosutural Dysplasia | Bietti Crystalline Dystrophy | Celiac Disease | Restrictive Dermopathy | Platelet Disorders | Nephronophthisis