Meningeal Melanocytoma

About the Disease
Meningeal Melanocytoma, also known as leptomeningeal melanocytoma, is related to congenital lipomatous overgrowth, vascular malformations, and epidermal nevi and neurilemmoma, and has symptoms including headache, vomiting and neurologic symptoms. An important gene associated with Meningeal Melanocytoma is GNAQ (G Protein Subunit Alpha Q), and among its related pathways/superpathways are Signal Transduction and ADORA2B mediated anti-inflammatory cytokines production. The drugs Bevacizumab and Antineoplastic Agents, Immunological have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and temporal lobe, and related phenotypes are limbs/digits/tail and pigmentation

Common Targets
GNAQ | G672 | GSTP1

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