Myopia

About the Disease
Myopia, also known as near-sightedness, is related to night blindness, congenital stationary, type 1a and degenerative myopia, and has symptoms including aniseikonia An important gene associated with Myopia is FBN1 (Fibrillin 1), and among its related pathways/superpathways are Extracellular matrix organization and Syndecan-1-mediated signaling events. The drugs Fluorometholone and Loteprednol etabonate have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and endothelial.

Common Targets
AHI1 | MICAL3 | C2 | CA4 | PYROXD1 | TCF7L2 | GRB2 | OPA3 | PRKACB | TJP2 | SLC39A8 | DIAPH2 | OFD1 | PLCB4 | ZNRF3 | TMEM98 | G7422 | FBXW11 | SHISA6 | PRDX1 | SPAG17 | B4GALNT2 | TNKS | ZBTB38 | OTX2 | AP1B1 | COL8A1 | PSEN1 | WNT7B | COL18A1 | MROH2A | AKAP12 | FAM161A | CFB | ACAN | SOCS1 | ALDH1A2 | OSBPL3 | RBFOX1 | GUCY2D | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | RBMXL3 | CEP128 | TGIF1 | FBN1 | ZMAT4 | LUM | SRF | DUOX2 | SNRNP200 | PROSER2 | PAX2 | LRFN5 | Gamma-Aminobutyric acid type B receptor | ITM2B | ZNF644 | PRPH2 | RASGRF1 | COL1A1 | CFD | HS3ST4 | XRCC2 | ADCY3 | TRMT44 | PRDX5 | MGRN1 | FZD4 | UPK2 | BMP3 | ROCK1 | G3725 | ZEB2 | MYOC | TIMM50 | SKP1 | CHRM1 | RHO | G3479 | COL9A1 | TMPO | SORBS3 | BTRC | CRX | ROM1 | MIR548H4 | MIR2277 | EXOC7 | CPSF1 | NEXMIF | MIR100HG | BICC1 | SYN3 | MIR548G | PPP3CC | TOPORS | MICU2 | ANGPTL2 | LOC105374009 | LRPAP1 | DLG2 | PDE6C | PRPF8 | OPN1LW | CTNNBIP1 | MIR328 | RDH5 | MIR423 | PRPF6 | CEP290 | TMEM187 | ABCA1 | SNTB1 | TBL1XR1 | GUCA1B | CMSS1 | CTSH | P3H2 | KRT12 | ELAPOR1 | NLK | BLOC1S1-RDH5 | EFEMP1 | LRIT2 | SLC16A2 | ALDH1A1 | IBTK | OXT | MFN2 | JAG1 | TSPAN12 | DNAH12 | FGB | MAGT1 | RGS5 | HOXA2 | IMPG1 | CAPN8 | FGF10 | SEMA4A | VIPR2 | SAGE1 | MAML2 | CPD | ARMS2 | SOD3 | MIR636 | RBP3 | RP2 | KCNQ5 | PPFIA2 | RIMS1 | G2475 | KMT2A | G3480 | PPP1R3B | LAMA2 | ARFGEF2 | CR1 | RPGR | LAMA1 | CSNK2B | FBXO31 | BEST1 | RSPO1 | KCNMA1 | USH2A | LINC02456 | OPN1SW | PDE11A | SLC39A5 | LOC105369944 | Adenosine receptor (nonspecified subtype) | CAPN5 | IL31RA | VCX | FARP2 | PAX6 | RB1 | ATL3 | USPL1 | AKR1B10 | RBX1 | RGR | PRSS56 | G7157 | GJD2 | Muscarinic Acetylcholine Receptor (mAChR) (nonspecified subtype) | LOXL3 | Complement Complex | LRRC4C | COL11A1 | OPA1 | ACTC1 | NR3C1 | MSRA | SCO2 | TREX1 | C3 | NDUFAF7 | G3082 | SFRP1 | CFH | OPN1MW | CPTP | KLHDC8B | ODF2L | NYX | MMP2 | SLC66A2 | SLITRK6 | MIR6737 | LOC642846 | COL2A1 | NT5DC1 | VDR | CC2D2A | G4233 | KATNIP | ANPEP | CTNND2 | ALDH1A3 | GNAT1 | P4HA2 | CACNA1F | RAB3C | PEX13 | OPTC | APOE | CLDN23 | CSAG1 | PDGFRA | RWDD4 | CYB5B | PRIMPOL | MIR7704

Note: If you'd like to get a target analysis report for Myopia, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Myopia at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

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