Disease

Neurodevelopmental Disorders

About the Disease
Cerebellar Atrophy, Developmental Delay, and Seizures, also known as neurodevelopmental disorders, is related to chd2-related neurodevelopmental disorders and attention deficit-hyperactivity disorder. An important gene associated with Cerebellar Atrophy, Developmental Delay, and Seizures is KCNMA1 (Potassium Calcium-Activated Channel Subfamily M Alpha 1). The drugs Methylphenidate and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include brain, prefrontal cortex and heart, and related phenotypes are eeg abnormality and global developmental delay

Common Targets
KPTN | PCGF2 | TARDBP | MYO15A | FBXL3 | EMC10 | BICRA | MED13 | Gamma-Aminobutyric acid type B receptor | RAC1 | OGDH | CDC42BPB | ASXL2 | THOC2 | H3-3B | FAM184A | CSNK1G1 | RHOBTB2 | KCNQ3 | SLC35A2 | ADNP | SMARCA2 | ATP6V0A1 | PUF60 | YY1 | HDAC3 | VARS1 | CTR9 | SLC6A8 | ADGRG1 | ATG7 | ERCC6 | KDM5C | BCL11A | SLC19A3 | INTS1 | TNRC6A | G5594 | DAB1 | DYNC1H1 | DYRK1A | DENND5A | CHD1 | WARS1 | NTRK1 | CIC | GNAO1 | ARF3 | PTCH1 | WDR62 | BRF1 | SLC1A4 | ZEB2 | SCN8A | VPS41 | CHRNA7 | OTUD6B | GRIA1 | GSK3B | PCDH19 | NCDN | WWOX | MORC2 | DROSHA | VPS13B | CACNA1C | DHX30 | SHANK2 | ALDH3A2 | PUS7 | TCF4 | AP4B1 | SKIC3 | SMC1A | CHD5 | PRRT2 | CAPRIN1 | OCLN | MFSD2A | GEMIN4 | MECP2 | YWHAG | GPT2 | PRICKLE2 | PPP2R5C | GRIN2D | CSNK2A1 | ATP7A | JMJD1C | CHD2 | PYCR1 | MOCS1 | MTHFS | NCKAP1 | JPH3 | TLK2 | QRICH1 | IMPA1 | CLN6 | SETD5 | WDR81 | EIF4A2 | TRAPPC10 | VPS11 | G4137 | GRIA2 | SMARCA4 | DNM1L | PIGC | FARSA | SRD5A3 | HNRNPH2 | GRIN2A | SPATA5 | RERE | GFPT1 | FOXP1 | SMG8 | VPS51 | GEMIN5 | KAT6A | KMT2B | ARHGEF9 | PCDH12 | SPOP | WAC | PTRH2 | STRADA | WDR45 | NSD1 | ACSL4 | PIGH | CHD7 | ALDH18A1 | NRCAM | POGZ | CARS2 | CDH15 | KMT2E | TRAPPC2L | GRM7 | PRPF8 | UGDH | KDM3B | PUS3 | TTC19 | TRAPPC6B | UPF3B | SLC13A5 | DCAF1 | CLP1 | SCAF4 | HNRNPU | ERCC8 | RING1 | SARS1 | SOX3 | SPTAN1 | GRIA3 | MAB21L1 | G472 | NF1 | TBL1XR1 | PPFIBP1 | SLC16A1 | SZT2 | PUM1 | SET | KCNC3 | KMT2A | EIF3F | VPS13D | KATNB1 | ZC4H2 | TBX4 | AARS2 | GABRA1 | AP4S1 | ADCY5 | ATP2B1 | TRMT10A | EPG5 | NAA10 | CTNNB1 | SOX4 | SRCAP | PAN2 | EMILIN1 | DLG3 | CRPPA | TUBB6 | SMARCC2 | MID1 | TANGO2 | PPP2R5D | GRIA4 | KMT2D | BCORL1 | SCN1A | OTUD5 | TTN | NIPBL | ANKRD11 | CHD3 | IMPDH2 | PI4KA | SLC25A12 | PTPN11 | SPAST | SLC6A19 | SMS | HERC2 | DHX38 | DHDDS | ALS2 | MBOAT7 | BLTP1 | ADARB1 | L1CAM | CUL3 | OGDHL | DHPS | LTBP1 | MAPK8IP3 | PDE2A | GLRA3 | MAPRE2 | NUS1 | PNKP | SLC45A1 | COG4 | CDH2 | FAM104B | TBCK | C12orf4 | KIF11 | ATP1A3 | CLCN2 | TRAPPC4 | ITGA7 | MYH3 | HK1 | SPTBN4 | NAGLU | MYLK | BCL11B | SLC2A1 | CACNA1A | BPTF | MAPKAPK5 | MTA2 | NSD2 | GABRA5 | PIGV | DLL1 | DNAJC6 | KIF14 | PURA | EEF1A2 | IFIH1 | CUX1 | ARID1A | KCNT1 | NFIX | KDM6B | PIGN | CLEC16A | CHD8 | GTPBP2 | GJC2 | ZNF699 | KCNMA1 | PPFIA2 | KCNT2 | ATN1 | CLTC | GTF2IRD1 | SPTBN2 | ZBTB7A | DOCK3 | CSF1R | IQCJ-SCHIP1 | SYN1 | BRSK2 | SLC6A1 | TACO1 | GABRD | TCEAL1 | PI4K2A | CLCN4 | ADGRL1 | BRAT1 | SMARCB1 | FZR1 | HTT | TSPYL2 | BCKDK | PAK1 | AKT3 | HIRA | PPFIA1 | CTCF | SYN2 | GRIN2B | TFE3 | CABIN1 | ENTPD1 | TRIO | KIF21A | SCHIP1 | TECPR2 | KCNH1 | NARS1 | ALDH5A1 | PACS2 | SIN3A | CHD4 | STX1B | WDR45B | P4HTM | EXOSC5 | PPP1R21 | GAD1 | BCAS3 | DDX3X | STX1A | PEX1 | PRR12 | NTRK2 | NSUN2 | NTNG2 | DEAF1 | SIAH1 | AGMO | SYT1 | PDHA1 | SNAPC4 | WDFY3 | OCRL | APC2 | CACNB4 | ROBO1 | PIDD1 | UBR7 | PRUNE1 | SLC38A8 | DDB1 | SCAMP5 | MEIS2 | HCFC1 | CYP27B1 | KIF1A | GRN | SETD1B | KDM4B | CSPP1 | CLPB | KAT5 | SOX11 | BTD | GCDH | KCNQ2 | EEF1B2 | CACNA1I | ALKBH8 | ODC1 | MED12 | NCAPG2 | RAB39B | ARSA | SCN2A | FGFR3 | C18orf32 | RUBCN | STXBP1 | KMT5B | GCNT2 | EEF2 | PIGT | GMPPB | GRIN3A | KCNA2 | SEPHS1 | NALCN | ADAT3 | ALDOA | GSPT2 | ZMIZ1 | TUBB2A | FOXG1 | AUTS2 | LRRK2 | CAMSAP1 | CNOT3 | MLC1 | TRPM3 | PHIP | PPT1 | HECW2 | NFASC | ABCD1 | ATP1A2 | ALG1 | ITPR1 | PRNP | STAG2 | CP | TTI1 | MIR218-1 | LAMC3 | KCNN2 | IQSEC2 | EXOC3L2 | TASP1 | AGO1 | CYFIP2 | NPHP1 | CCNK | COQ4 | CPZ | MAOA | H4C11 | AHI1 | NF2 | EFNB2 | TUBB3 | ACTB | NONO | EXOC8 | CHD9 | KMT2C | TAOK1 | NT5C2 | MBD5 | TUBB | NCOA3 | CSMD3 | PGAP2 | MSL3 | NSRP1 | YIF1B | SOX6 | ARID1B | ZNF142 | MINAR1 | GNAI1 | DNM1 | FLCN | ALG13 | MED13L | CEP55 | H3-3A | DPH1 | DDX6 | TMEM94 | PSMD12 | GABBR1 | ATRX | CIP2A | PGAP1 | LNPK | SHANK3

疾病靶点研报
Neurodevelopmental Disorders

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