Malignant Peripheral Nerve Sheath Tumor

About the Disease
Malignant Peripheral Nerve Sheath Tumor, also known as malignant neurilemmoma, is related to malignant triton tumor and epithelioid malignant peripheral nerve sheath tumor. An important gene associated with Malignant Peripheral Nerve Sheath Tumor is NF1 (Neurofibromin 1), and among its related pathways/superpathways are Apoptotic Pathways in Synovial Fibroblasts and Disease. The drugs Doxorubicin and Cyclophosphamide have been mentioned in the context of this disorder. Affiliated tissues include lung, t cells and small intestine, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Common Targets
BRD4 | MAP2K1 | MAGEA4 | G4233 | CDA | G3845 | MAGEB2 | FLT3 | TAGLN | G4193 | Mitogen-Activated Protein Kinase (nonspecified subtype) | SUZ12 | G7015 | G7157 | KIT | TRAF7 | G673 | MAP2K2 | VCP | Glutaminase (nonspecified subtype) | RASSF1 | SMARCB1 | NRAS | CSF1R | MAP3K1 | DNA Methyltransferase (DNMT) (nonspecified subtype) | HRAS | Heat shock protein 90 (nonspecified subtype) | SSTR2 | NF2 | G1956

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