Disease

Diverticulitis

About the Disease
Diverticulitis is related to diverticulitis of colon and appendicitis. An important gene associated with Diverticulitis is NALF1 (NALCN Channel Auxiliary Factor 1), and among its related pathways/superpathways are Innate Immune System and Cytokine Signaling in Immune system. The drugs Gabapentin and Fentanyl have been mentioned in the context of this disorder. Affiliated tissues include colon, small intestine and appendix.

Common Targets
UPK1A | COLQ | GCK | MAP3K8 | NAT1 | ATP8B2 | TPR | CTNNB1 | ARHGAP15 | PDE7B | LAMB4 | HECW1 | NALF1 | Protein Phosphatase 2A | TAB2

疾病靶点研报
Diverticulitis

Note: If you'd like to get a target analysis report for Diverticulitis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Diverticulitis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Trichuriasis | Familial Mediterranean Fever | Palsy, Cerebral | Polymyositis | Nutrition Disorders | Ehlers-Danlos Syndrome | Myotonia | Anthrax | McKusick Type Metaphyseal Chondrodysplasia | Combined Deficiency Of Factor V And Factor VIII | Infantile Liver Failure Syndrome 1 | Crouzon Syndrome With Acanthosis Nigricans | Metatropic Dysplasia | Coronary Artery Disease | Pulmonary Stenosis | Leri-Weill Dyschondrosteosis | Mesothelioma, Malignant | Distal Myopathy | Meleda Disease | Nephroblastoma | Sarcomatoid Carcinoma Of The Lung | Adenoid Cystic Carcinoma | Hereditary Spastic Paraplegia | Oligospermia | 3-methylglutaconic Aciduria Type IV | Hypotrichosis | Muscular Dystrophy | Porphyria, Acute Intermittent | Pantothenate Kinase-associated Neurodegeneration | VEXAS Syndrome | Periventricular Nodular Heterotopia | Cutis Laxa | Nanophthalmos | GM2-gangliosidosis AB Variant | Rubinstein-Taybi Syndrome | Chromosome 16p11.2 Deletion Syndrome | Patent Ductus Arteriosus | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Hyperprolactinemia | Aspergillosis | Bartter Syndrome | Congenital Adrenal Hyperplasia 1 | Babesiosis | Spinal Muscular Atrophy Type 2 | Cutaneous T-cell Lymphoma | Myopia | Thin Basement Membrane Disease | Chronic Granulomatous Disease | Spinocerebellar Ataxia Type 15 | Diabetic Neuropathy | MELAS Syndrome | Papilledema | Colon Adenoma | Congestive Heart Failure | Inflammatory Bowel Disease | Congenital Nephrotic Syndrome | Acute Tubular Necrosis | Sclerosteosis 2 | Spondyloperipheral Dysplasia | Fibronectin Glomerulopathy | Diverticulitis | Anti-glomerular Basement Membrane Disease | Retinopathy Of Prematurity | Autonomic Nervous System Disorders | Cabezas Syndrome | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Nicotine Addiction | Familial Cerebral Amyloid Angiopathy | Erythromelalgia | Sleep Apnea, Obstructive | Tay-Sachs Disease | Apparent Mineralocorticoid Excess Syndrome | Hamartoma | Distal Myopathy 2 | Myelomeningocele | Hypersensitivity | Intestinal Tuberculosis | Schizencephaly | Glycogen Storage Disease | Conn Syndrome | Stroke, Hemorrhagic | Osteogenesis Imperfecta Type V | Polymyalgia Rheumatica | Gingivitis | Otopalatodigital Syndrome Type 2 | Hereditary Hemorrhagic Telangiectasia | Intracerebral Hemorrhage | Hyperoxaluria | Hypertriglyceridemia | Imerslund-Grasbeck Syndrome | Waardenburg Syndrome Type 2 | Osteoporosis | Cornelia De Lange Syndrome | Fetal Akinesia Deformation Sequence | Feingold Syndrome | Pachyonychia Congenita | Neurofibromatosis Type 2 | Klinefelter Syndrome | Infectious Diarrhea | Chordoid Glioma | Spinocerebellar Ataxia Type 42 | Polyradiculopathy | COACH Syndrome | Hemochromatosis Type 1 | Infantile Refsum Disease | HUPRA Syndrome | Neurofibrosarcoma | Spondylocarpotarsal Synostosis Syndrome | Raynaud Phenomenon | Sarcoidosis, Pulmonary | Myoclonus-dystonia Syndrome | Warsaw Breakage Syndrome | Ichthyosis | Currarino Syndrome | Depression | Relapsing Polychondritis | Ophthalmia, Sympathetic | Anosmia, Congenital | GATA2 Deficiency | Neural Tube Defect | Lipid Storage Myopathy | Gynecomastia | Chondrosarcoma | Neutrophilia | Charcot-Marie-Tooth Disease Type 3 | Schizophrenia, Paranoid | Metabolic Diseases | Glutaric Aciduria Type 1 | Cancer, Prostate | Esophageal Carcinoma | Trichotillomania | Colitis, Microscopic | Nemaline Myopathy 8 | Insulinoma | Fanconi Anemia | Pancreatitis | Long QT Syndrome Type 1 | Endometriosis | Diabetes Type 1 | Hypophosphatasia | ADNP Syndrome | Episodic Ataxia Type 2 | Angiomyolipoma | Non-proliferative Diabetic Retinopathy | Lymphoproliferative Disorders | AIDS Dementia Complex | Exostoses | Amyotrophic Lateral Sclerosis | Acute Kidney Injury | Noonan Syndrome | X-linked Myotubular Myopathy | Phenylketonuria | Alazami Syndrome | Kaposi Sarcoma | Neurocysticercosis | Basal Ganglia Disease, Biotin-responsive | Majeed Syndrome | Varicocele | Infertility, Male | Congenital Bile Acid Synthesis Defect | Ophthalmoplegia | Congenital Hypofibrinogenemia | Schistosomiasis | Zellweger Syndrome | Megalencephaly | Pierre Robin Syndrome | Sick Sinus Syndrome | Amish Infantile Epilepsy Syndrome | Mucolipidosis Type II | Acute Generalized Exanthematous Pustulosis | Kashin-Beck Disease | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Cavitary Optic Disc Anomalies | Dysthymia | Weill-Marchesani Syndrome | Hashimoto Thyroiditis | Malnutrition | Sickle Cell Disease | Schwartz-Jampel-Aberfeld Syndrome | Pulmonary Capillary Hemangiomatosis | Chronic Granulomatous Disease, X-linked | Larsen Syndrome | Cerebral Cavernous Malformations | Carcinoma, Transitional Cell | LRBA Deficiency | Peeling Skin Syndrome, Acral Type | Phosphoglycerate Dehydrogenase Deficiency | Mitochondrial Cytopathy | Wilson's Disease | Camptocormia | Delirium | Colitis, Lymphocytic | Epilepsy Of Infancy With Migrating Focal Seizures | Myasthenia Gravis | Fibrosis | Pycnodysostosis | Presbyopia | Gerstmann-Straussler-Scheinker Syndrome | Bernard-Soulier Syndrome | Carbonic Anhydrase VA Deficiency | CEDNIK Syndrome | Usher Syndrome | Enterocolitis, Necrotizing | Hyperandrogenemia | Keratitis | Pheochromocytoma | Allan-Herndon-Dudley Syndrome | Spastic Paraplegia Type 7 | Carcinoma, Small Cell | Neurogenic Bladder | Renal Dysplasia | Spinocerebellar Ataxia Type 10 | Epicondylitis | Diabetic Macular Edema | Oligodendroglioma | Hepatic Adenomatosis | Diamond-Blackfan Anemia | Atrioventricular Septal Defect | Kawasaki Disease | Diabetes Insipidus, Nephrogenic | Tangier Disease | Stuve-Wiedemann Syndrome | Erythrokeratodermia Variabilis | Aldosterone Synthase Deficiency | Sitosterolemia | Nemaline Myopathy | Primary Biliary Cholangitis | Motor Neuron Diseases | Spinocerebellar Ataxia Type 40 | Blue Rubber Bleb Nevus Syndrome | Absence Epilepsy | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Niemann-Pick Disease, Type C | Robinow Syndrome | Fukuyama Congenital Muscular Dystrophy | Epilepsy | Pneumonia, Viral | Wieacker-Wolff Syndrome | Hyperlipidemia | Chronic Inflammatory Demyelinating Polyneuropathy | Gastroschisis | Hypotonia-cystinuria Syndrome | Cholecystitis | Uveitis, Anterior | Osteosarcoma | Gastroenteritis, Eosinophilic | Arthritis, Psoriatic | Tietze Syndrome | Ghosal Syndrome | Common Cold | Congenital Dyserythropoietic Anemia | Cranioectodermal Dysplasia | Norrie Disease | Dental Caries | Arrhythmogenic Right Ventricular Cardiomyopathy | T-cell Prolymphocytic Leukemia | Polycystic Liver | Protein C Deficiency | Leprosy | Cold-induced Sweating Syndrome | Coenzyme Q10 Deficiency | Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis | Stickler Syndrome | Mitochondrial Encephalomyopathy | Focal Dermal Hypoplasia | Familial Thoracic Aortic Aneurysm | Bronchiectasis | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Carbamoyl Phosphate Synthetase I Deficiency | Acrocallosal Syndrome | Hypersensitivity Pneumonitis | CHOPS Syndrome | Tyrosine Hydroxylase Deficiency | Anencephaly | Liver Failure, Acute Infantile | Chronic Thromboembolic Pulmonary Hypertension | Cousin Syndrome | Ameloblastoma | Epidermal Nevus Syndrome | Chudley-McCullough Syndrome | Hydrocephalus | Marfan Syndrome | Rift Valley Fever | FG Syndrome | Perry Syndrome | Craniosynostosis | Renal Hypouricemia | Familial Hypobetalipoproteinemia | Cholangiocarcinoma | Cohen Syndrome | Eclampsia | Hernia, Inguinal | Familial Hemiplegic Migraine | Methemoglobinemia | Fibromyalgia | Chediak-Higashi Syndrome | Cryptosporidiosis | Paraganglioma, Carotid Body | Spinocerebellar Ataxia Type 1 | Pulmonary Sclerosing Hemangioma | Pyloric Stenosis, Infantile Hypertrophic | Glycogen Storage Disease Type 1b | Ependymoma | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Osteogenesis Imperfecta Type III | Fuchs Heterochromic Iridocyclitis | Camurati-Engelmann Disease | Schizoaffective Disorder | Liver Failure | Hyperthyroidism | Hypospadias | Neovascular Glaucoma | Transcobalamin Deficiency | Diabetes Type 2 | Plasma Cell Leukemia | Diffuse Mesangial Sclerosis | Nail Disorder, Nonsyndromic Congenital | Pontocerebellar Hypoplasia Type 7 | VACTERL/VATER Association | Familial Isolated Hyperparathyroidism | Trichorhinophalangeal Syndrome | Amyotrophic Lateral Sclerosis, Juvenile | T-cell Leukemia | Pseudohypoparathyroidism Type 1C | Gigantism | Communication Disorders | Compartment Syndrome | Spina Bifida | Cryopyrin-associated Periodic Syndromes | Carcinoma, Merkel Cell | Primary Erythromelalgia | Trichomegaly | Sarcoma, Endometrial Stromal | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Melanocytic Nevus | Precocious Puberty | Myocardial Infarction | Gestational Trophoblastic Disease | Cholelithiasis | Polycythemia | Lymphangioleiomyomatosis | Plasma Cell Dyscrasia | Keratopathy | Trichothiodystrophy | Schwannomatosis | Melanoma, Malignant | Sporadic Hemiplegic Migraine | Spinocerebellar Ataxia Type 38 | Spondyloarthritis | Gastritis, Atrophic | Pseudomyxoma Peritonei | Reflex Epilepsy | Ataxia-ocular Apraxia 2 | Pulmonary Veno-occlusive Disease | Temporal Lobe Epilepsy | Schnyder Crystalline Corneal Dystrophy | Dowling-Degos Disease | Ileitis | Spondyloepiphyseal Dysplasia Tarda, X-linked | Chromosome 9q34.3 Deletion Syndrome | Left Ventricular Noncompaction | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Guanidinoacetate Methyltransferase Deficiency | Mountain Sickness | Sertoli Cell-only Syndrome | Dwarfism | Charcot-Marie-Tooth Disease Type 4B1 | PASLI Disease | Hyperthermia, Malignant | Distal Spinal Muscular Atrophy | Macrodactyly | Persistent Fetal Circulation | Hypothyroidism | Epidermolytic Hyperkeratosis | Chorea | Limb Girdle Muscular Dystrophy | Orotic Aciduria | Infantile Neuroaxonal Dystrophy | Birk-Barel Syndrome | Stromal Corneal Dystrophy | Polymicrogyria | Obesity, Morbid | Pelvic Inflammatory Disease | B-cell Prolymphocytic Leukemia | Cervicitis | Paternal Uniparental Disomy Of Chromosome 14 | Charcot-Marie-Tooth Disease, Type 2C | Porphyria Cutanea Tarda | Cholera | Atelosteogenesis Type 2 | Necrotizing Autoimmune Myopathy | Charcot-Marie-Tooth Disease, Type 6 | Vitiligo | Blepharo-cheilo-odontic Syndrome | Carcinoid Syndrome | Genee-Wiedemann Syndrome | Hypogonadism | Sick Sinus Syndrome 1 | Pseudohypoparathyroidism Type 1B | Evans Syndrome