Disease

Oligospermia

About the Disease
Oligospermia is related to androgen insensitivity, partial and varicocele. An important gene associated with Oligospermia is MSH4 (MutS Homolog 4), and among its related pathways/superpathways is C-MYB transcription factor network. The drugs Letrozole and Anastrozole have been mentioned in the context of this disorder. Affiliated tissues include testes, testis and pituitary, and related phenotypes are endocrine/exocrine gland and growth/size/body region

Common Targets
PRMT6 | MSH3 | CYP2D6 | HLA-DRB1 | KDM3A | G7124 | SOHLH1 | MAEL | ESR2 | DNMT3L | FSHR | DDX4 | H2BW1 | MIR34B | MTRR | KITLG | FAM47C | NR5A1 | GSTT1 | INSR | SIRPA | YBX2 | SOX8 | MIR34C | G367 | ZMYND15 | MLH3 | SOX5 | MTHFR | MTHFD1 | UBR2 | NANOS1 | CBS | BOLL | NOS3 | IL1A | NR0B1 | M1AP | FKBP6 | WT1 | EPSTI1 | CFTR | GPRC6A | GSTM1 | SIRPG | RER1 | CYP19A1 | USP8 | SPATA16 | HORMAD1 | PRM1 | MEST | PRM2 | MTR | MLH1 | MSH2 | KIT | H19 | MIR499A | NFKB1 | SHMT1 | PEX10 | TAF7L | IL1RN

疾病靶点研报
Oligospermia

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