Dystonia Musculorum Deformans

About the Disease
Dystonia 1, Torsion, Autosomal Dominant, also known as dystonia musculorum deformans 1, is related to dystonia 6, torsion and torticollis, and has symptoms including dystonia, myoclonus and torticollis. An important gene associated with Dystonia 1, Torsion, Autosomal Dominant is TOR1A (Torsin Family 1 Member A). The drug Botulinum Toxins has been mentioned in the context of this disorder. Affiliated tissues include globus pallidus, brain and subthalamic nucleus, and related phenotypes are hyperreflexia and dysarthria

Common Targets
GCH1 | ANO3 | ADCY5 | TOR1A

Note: If you'd like to get a target analysis report for Dystonia Musculorum Deformans, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Dystonia Musculorum Deformans at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Familial Glucocorticoid Deficiency | Thrombosis | Glutaric Aciduria Type 2 | Acute Generalized Exanthematous Pustulosis | Hypoproteinemia, Hypercatabolic | Familial Male-limited Precocious Puberty | Abetalipoproteinemia | Charcot-Marie-Tooth Disease, Type 2C | Protein S Deficiency | Hypopituitarism | Alopecia Areata | Esophageal Adenocarcinoma | Metachondromatosis | Tinea Versicolor | Renal Hypouricemia | Hyperglycemia | Lymphoma, Follicular | Melanoma, Uveal | Aldosterone Synthase Deficiency | Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy | Trismus-pseudocamptodactyly Syndrome | Hypophosphatasia | Multiple Sulfatase Deficiency | Primary Sclerosing Cholangitis | Riboflavin Transporter Deficiency Neuronopathy | GM2-gangliosidosis AB Variant | Osteogenesis Imperfecta Type I | Cancer, Breast | Postaxial Polydactyly | Chondroma | Vitamin K Deficiency | Trigonocephaly | Varicocele | Mitochondrial DNA Depletion Syndrome, Encephalomyopathic Form | Pancytopenia | Phenylketonuria | Loeys-Dietz Syndrome Type 4 | Sleep Apnea | Silicosis | Ichthyosis, X-linked | Spinocerebellar Ataxia Type 10 | Ameloblastic Carcinoma | Spinocerebellar Ataxia Type 8 | Colitis | Aicardi-Goutieres Syndrome | Japanese Encephalitis | Myocarditis | Neuromyotonia | Ebstein Anomaly | Gingivitis | Epidermolysis Bullosa Simplex, Generalized | Chronic Inflammatory Demyelinating Polyneuropathy | Metatropic Dysplasia | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Enhanced S-cone Syndrome | Meningococcal Meningitis | Choriocarcinoma | Kabuki Syndrome | Psoriasis | Snyder-Robinson Syndrome | Epidermolysis Bullosa Simplex | Hypermetropia | Schaaf-Yang Syndrome | Adult Polyglucosan Body Disease | Pemphigus Vulgaris | Thalassemia | Guanidinoacetate Methyltransferase Deficiency | Osteoporosis-pseudoglioma Syndrome | Neutrophilia | 5-oxoprolinase Deficiency | Myasthenia Gravis | Cervicitis | Spinocerebellar Ataxia Type 14 | Ectopia Lentis, Isolated, Autosomal Recessive | Macrodactyly | Wiedemann-Steiner Syndrome | Prolidase Deficiency | Hereditary Spherocytosis | Lymphoma Lymphoblastic | Charcot-Marie-Tooth Disease Type 4 | Antiphospholipid Syndrome | Kashin-Beck Disease | Lichen Planus | Eosinophilic Asthma | Neuroectodermal Tumors, Primitive | Desmosterolosis | Woodhouse-Sakati Syndrome | Carpal Tunnel Syndrome | Tay-Sachs Disease | Chronic Myelomonocytic Leukemia | Spondylometaphyseal Dysplasia | Sclerosteosis 2 | Non-proliferative Diabetic Retinopathy | Schizoaffective Disorder | Keratitis-ichthyosis-deafness Syndrome | Heterotaxy | Early Infantile Epileptic Encephalopathy | Pneumonia, Bacterial | Okihiro Syndrome | Epidermolytic Ichthyosis, Annular | Dystrophy, Cone-rod | TARP Syndrome | Nephronophthisis | Chondromyxoid Fibroma | Carpenter Syndrome | Combined Malonic And Methylmalonic Acidemia | Familial Episodic Pain Syndrome | Hyperthermia, Malignant | Shock, Cardiogenic | Intellectual Disability, Autosomal Dominant 5 | Retinitis Pigmentosa | Orthostatic Intolerance | Primary Hyperoxaluria Type 3 | 3-methylglutaconic Aciduria | Pituitary Dwarfism | Hyperuricemic Nephropathy, Familial Juvenile | Imerslund-Grasbeck Syndrome | Pleural Tuberculosis | Eosinophilia | Lymphedema-distichiasis Syndrome | Fahr Disease | Hemophilia | Vascular Calcification | Pelizaeus-Merzbacher Disease | Leishmaniasis, Visceral | Anosmia, Congenital | Non-bullous Congenital Ichthyosiform Erythroderma | Hepatitis E | Gliosarcoma | Neurofibroma | B-cell Prolymphocytic Leukemia | Hepatorenal Syndrome | Pyruvate Carboxylase Deficiency Disease | Hartsfield Syndrome | Autoimmune Hemolytic Anemia | Gangliosidosis | Ichthyosis | Jalili Syndrome | Creatine Deficiency Syndrome Due To AGAT Deficiency | Juvenile Myelomonocytic Leukemia | Colorectal Adenoma | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Neuroma | Primary Hyperoxaluria Type 1 | Idiopathic Multicentric Castleman Disease | Oligoasthenoteratozoospermia | Turner's Syndrome | Personality Disorders | Asphyxia Neonatorum | Ocular Hypertension | Cholestasis, Intrahepatic | Congenital Myasthenic Syndrome | Palmoplantar Keratoderma | Becker Muscular Dystrophy | Peripheral T-cell Lymphoma | Vascular Cognitive Impairment | Sponastrime Dysplasia | Fundus Albipunctatus | Zollinger-Ellison Syndrome | Hypoglycemia | Glycogen Storage Disease Type 5 | Pompe Disease | Cardiac Sarcoidosis | Oculocutaneous Albinism | Marinesco-Sjogren Syndrome | Chitayat Syndrome | Lamellar Ichthyosis | Measles | Lymphoma, Mantle Cell | Harlequin Ichthyosis | Autonomic Neuropathy | Cyclic Vomiting Syndrome | Glycogen Storage Disease Type 6 | Chylomicron Retention Disease | Optic Nerve Hypoplasia, Bilateral | Infertility | Carbohydrate Metabolism Disorders | Borderline Personality Disorder | Sertoli Cell-only Syndrome | Osteomyelitis | Chordoma | Oculocutaneous Albinism Type 2 | Progressive Encephalopathy-optic Atrophy Syndrome | Ophthalmoplegia | Pontocerebellar Hypoplasia | Tangier Disease | Liddle Syndrome | Ovarian Sex Cord-stromal Tumor | Sotos Syndrome | Leber Congenital Amaurosis | Hyperinsulinism-hyperammonemia Syndrome | Corneal Dystrophy And Perceptive Deafness | Rubeosis Iridis | Cutaneous T-cell Lymphoma | NDH Syndrome | Juvenile Myoclonic Epilepsy | Carcinoma, Signet Ring Cell | Obesity | Thin Basement Membrane Disease | Exfoliative Dermatitis | Trichotillomania | Phosphoglycerate Dehydrogenase Deficiency | Stuttering | Granular Corneal Dystrophy Type 1 | Combined Pituitary Hormone Deficiency | Tularemia | Oligodendroglioma | Proopiomelanocortin Deficiency | Erythromelalgia | Angioedema, Acquired | Spinocerebellar Ataxia Type 20 | Autoimmune Polyendocrine Syndrome | Pyloric Stenosis, Infantile Hypertrophic | Congenital Diaphragmatic Hernia | Renpenning Syndrome | Stargardt Disease | Schnitzler Syndrome | Chiari Malformation Type I | Porphyria, Variegate | Congenital Bile Acid Synthesis Defect | Nephritis, Interstitial | Trichomegaly | Galloway-Mowat Syndrome | Asthma, Exercise-induced | Osteosclerosis | Urea Cycle Disorder | Mitochondrial DNA Depletion Syndrome | Hyperuricemia | Anti-glomerular Basement Membrane Disease | Hyper IgE Syndrome | Coronary Heart Disease | Purpura, Thrombotic Thrombocytopenic | Depression | Facioscapulohumeral Muscular Dystrophy Type 2 | Bladder Exstrophy | Zygomycosis | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Anterior Segment Dysgenesis | Glycogen Storage Disease Type 0 | Meleda Disease | Gray Platelet Syndrome | Facioscapulohumeral Muscular Dystrophy Type 1 | Ichthyosis Hystrix, Curth-Macklin Type | Cancer, Colon | Arthrogryposis | Hennekam Lymphangiectasia-lymphedema Syndrome | Pseudo-pseudohypoparathyroidism | Urolithiasis | Biotinidase Deficiency | Hidradenitis Suppurativa | Menetrier Disease | Optic Neuritis | Panniculitis | Bullous Pemphigoid | Porencephaly | Bipolar Disorder | Thrombophilia | Hyperekplexia | Rubinstein-Taybi Syndrome | Metachromatic Leukodystrophy | Supravalvular Aortic Stenosis | Waardenburg Syndrome Type 2A | Ganglioglioma | Melanocytic Nevus | Carcinoma, Merkel Cell | Dyggve-Melchior-Clausen Disease | Mood Disorder | Cardiomyopathy, Hypertrophic | Distal Myopathy | Polyarteritis Nodosa | Prurigo Nodularis | Thymoma, Malignant | Meconium Ileus | Reflex Epilepsy | Filariasis | Rash | Esotropia | Usher Syndrome Type I | Angiodysplasia | Autosomal Recessive Spastic Paraplegia Type 75 | Alstrom Syndrome | Multicentric Carpotarsal Osteolysis Syndrome | Acromegaly | Craniolenticulosutural Dysplasia | Hereditary Neuropathy With Liability To Pressure Palsies | Pantothenate Kinase-associated Neurodegeneration | Charcot-Marie-Tooth Disease Type 4D | Hepatopulmonary Syndrome | Glycogen Storage Disease Type 1 | T-cell Lymphoma, Subcutaneous Panniculitis-like | Chronic Lymphocytic Leukemia | Encephalopathy, Glycine | Congenital Nephrotic Syndrome | Hyperparathyroidism, Primary | Carcinoid Tumor | Stroke | Microphthalmia | Pontocerebellar Hypoplasia Type 2 | Chordoid Glioma | Left Ventricular Noncompaction | Carcinoma In Situ | Autoimmune Polyendocrinopathy Syndrome Type I | Liver Failure | Amelanotic Melanoma | Pemphigoid | Diverticulitis | Niemann-Pick Disease, Type C | Bardet-Biedl Syndrome | Non-Langerhans Cell Histiocytosis | Menkes Disease | Erythematotelangiectatic Rosacea | Large Granular Lymphocytic Leukemia | Osteogenesis Imperfecta Type II | Syphilis | Hyperparathyroidism-jaw Tumor Syndrome | Purpura | Paroxysmal Nocturnal Hemoglobinuria | Cockayne Syndrome | Prediabetes | Frontotemporal Dementia | Hypotonia-cystinuria Syndrome | Chorea-acanthocytosis | Lentigo | Hepatitis, Chronic | Acute Chest Syndrome | Parvovirus B19 Infection | Waldenstrom Macroglobulinemia | Poretti-Boltshauser Syndrome | Renal-hepatic-pancreatic Dysplasia | Diabetic Neuropathy | Gynecomastia | Fragile X Syndrome | Kawasaki Disease | Hypertension, Portal | Epidermolysis Bullosa Dystrophica | Keratoconus | Diabetic Encephalopathy | Pericarditis | Benign Hereditary Chorea | Pure Red Cell Aplasia | Chronic Beryllium Disease | Niemann-Pick Disease | 3-methylglutaconic Aciduria Type I | Syndactyly | Stuve-Wiedemann Syndrome | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Transient Bullous Dermolysis Of The Newborn | Hepatic Steatosis | Tracheal Disorders | Brachial Plexus Neuropathy | Chondrosarcoma | Congenital Primary Aphakia | Thanatophoric Dysplasia | Vestibular Disease | Hypertriglyceridemia | Maple Syrup Urine Disease | Chudley-McCullough Syndrome | Cystinosis | Superficial Spreading Melanoma | Colitis, Microscopic | Spina Bifida | Pterygium | Spondyloepimetaphyseal Dysplasia With Joint Laxity, Type 3 | Glycogen Storage Disease Type 9 | Bronchiolitis | Infantile Spasm | Amyloidosis | Pernicious Anemia | Best Macular Dystrophy | Conjunctivitis, Allergic | Epiphyseal Chondrodysplasia, Miura Type | Optic Neuropathy | Hyperoxaluria | Hypospadias | Hyperlipidemia Type V | Primary Familial Brain Calcification | Mitochondrial Cytopathy | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Angina Pectoris | Saul-Wilson Syndrome | Agammaglobulinemia | Schnyder Crystalline Corneal Dystrophy | Neurotoxicity | Nager Acrofacial Dysostosis | Ectodermal Dysplasia | Peeling Skin Syndrome, Acral Type | Hypothyroidism | Uveitis, Anterior | Dysplastic Nevus | Eclampsia | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Blepharophimosis Syndrome | Diabetes Insipidus, Nephrogenic | Hemosiderosis | X-linked Acrogigantism | Neurodevelopmental Disorders | Familial Mediterranean Fever | Otitis Externa | Brooke-Spiegler Syndrome | Anal Fissure