Primary Hyperoxaluria Type 3

About the Disease
Hyperoxaluria, Primary, Type Iii, also known as primary hyperoxaluria type 3, is related to primary hyperoxaluria and nephrolithiasis, calcium oxalate. An important gene associated with Hyperoxaluria, Primary, Type Iii is HOGA1 (4-Hydroxy-2-Oxoglutarate Aldolase 1), and among its related pathways/superpathways are PERK regulates gene expression and Glyoxylate metabolism and glycine degradation. The drugs Omalizumab and Mupirocin have been mentioned in the context of this disorder. Affiliated tissues include kidney, pancreas and skeletal muscle, and related phenotypes are hematuria and nephrocalcinosis

Common Targets
HOGA1

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