Disease

Parkinson's Disease

About the Disease
Parkinson Disease, Late-Onset, also known as parkinson disease, is related to hereditary late-onset parkinson disease and parkinson disease 3, autosomal dominant, and has symptoms including angina pectoris, back pain and headache. An important gene associated with Parkinson Disease, Late-Onset is MAPT (Microtubule Associated Protein Tau), and among its related pathways/superpathways is Parkinson's disease pathway. The drugs Idebenone and Tadalafil have been mentioned in the context of this disorder. Affiliated tissues include Brain, and related phenotypes are hallucinations and abnormal autonomic nervous system physiology

Common Targets
TRIM3 | G59272 | BCR | G4609 | TRIM17 | CHRM1 | HTR1F | GPR119 | NR1H2 | Interleukin-1 (nonspecified subtype) | KCND3 | SLC1A3 | PIK3CB | LOC105377329 | PM20D1 | Estrogen receptor (nonspecified subtype) | SARM1 | PTBP1 | KEAP1 | Gamma-Aminobutyric acid type B receptor | ITIH1 | NUCKS1 | GAPDH | Nicotinic alpha4beta2alpha5 Receptor | DRD4 | TOX3 | Calpain (nonspecified subtype) | Lipoxygenase (nonspecified subtype) | mTOR complex 1 | m-Calpain | LCK | SYT17 | TAFA5 | ADORA1 | G7295 | VASH2 | GABRA4 | G842 | GPR88 | PRMT6 | SPCS3 | MTNR1A | SPG11 | ABI3 | GRIK1 | LOC102724081 | PDXK | HDAC8 | SLC26A1 | HTR2B | DNA Topoisomerase II (nonspecified subtype) | ALOX5AP | PDE8A | Serine/Threonine Kinase (nonspecified subtype) | IL10 | IL13RA1 | GABRG2 | ZNF521 | GRIN1 | MGLL | ADRA2B | NOS3 | LAG3 | SYNJ1 | MUC19 | CTNNA3 | Nicotinic alpha6beta2alpha4beta2beta3 receptor | MAP3K5 | C9orf72 | FKBP4 | GCH1 | ICAM1 | RABEP2 | ATP6V0A1 | T-Type Calcium Channel | Phosphodiesterase 1 (PDE1) (nonspecified subtype) | DAO | MAX | TRPV2 | TMEM175 | PLA2G4A | HDAC3 | FAM171A2 | CCNH | FOXK2 | GLIS3 | MIR133A1 | COX3 | TMEM9 | PTPN7 | HTRA2 | GRIN2C | LRBA | ZNF438 | FLT3 | CASP8 | ATG7 | PMVK | PLK2 | PGLYRP1 | CDK5 | RAI1 | Calcium/calmodulin-dependent protein kinase (nonspecified subtype) | ADORA2A | G6352 | BSG | MIR133A2 | TRPC5 | CA1 | MEGF10 | MIR4697 host gene (non-protein coding) | LOC105377374 | PRMT8 | PSMB9 | G3480 | CDK5/p25 | ADORA2B | EIF4A1 | MAP3K9 | G3479 | DYRK1A | NTRK1 | KRT18P55 | ABCA7 | Hedgehog Protein (nonspecified subtype) | ARHGAP27 | MITF | PDE10A | NOD2 | SYK | CCR2 | SLC16A9 | XDH | ALOX12 | MIR543 | GSTT1 | HMOX2 | HRH2 | RET | Nicotinic (alpha4beta2)2alpha4 receptor | SPR | DPP4 | CALD1 | GABRB2 | Cyclin-dependent kinase (nonspecified subtype) | G7422 | AVPR1B | Ephrin Receptor (nonspecified subtype) | CACNA1G | MARK4 | BMX | PSMD13 | PTCH1 | TLR2 | MTRR | GPR52 | HTR4 | SCD | CTC1 | G3605 | CDKAL1 | LOC102724428 | GPNMB | SLC22A13 | G7015 | OGG1 | P2RX3 | PDZK1 | Nicotinic (alpha4beta2)2beta2 receptor | CFAP95 | AQP4 | SLC7A5 | PDE8B | CCKBR | CELF1 | PTPN1 | G1/S-specific cyclin-E (nonspecified subtype) | UGCG | ARPP21 | G7157 | ND1 | MIR3681HG | CDK9/Cyclin T1 | SCN8A | Eukaryotic translation initiation factor 2-alpha kinase (nonspecified subtype) | MAP3K10 | VPS35 | SLCO2B1 | CHRNA7 | Neurotrophic Factor (nonspecified subtype) | AKR1B1 | DGAT2 | PPARD | CDK9 | GSK3B | SLC22A12 | Chymotrypsin (nonspecified subtype) | COL13A1 | CA12 | IP6K2 | TRRAP | MAPK11 | BTNL2 | ABCA1 | NTRK3 | ATP13A2 | FPR1 | ANKK1 | HPD | SIPA1L2 | SGK1 | SOD2 | CCN2 | SLC6A4 | NOTCH4 | HDAC7 | TMEM230 | Glutamate Transporter (nonspecified subtype) | BCHE | Acetylcholine Receptors (Nicotinic) (nAChR) (nonspecified subtype) | HNRNPA3 | CACNA1C | G836 | HTR2A | Steroid 5-alpha-Reductase (nonspecified subtype) | EIF4F translation-initiation complex | PDE1C | LAMP3 | alpha-Adrenoceptor (nonspecified subtype) | NF-kappaB (NFkB) | DBH | TMEM163 | ITGA8 | NDUFAF2 | SLC18A3 | PRDM2 | cGMP-Dependent Protein Kinase (nonspecified subtype) | DNAJC12 | TP53I3 | MCOLN1 | PTPN12 | CDNF | MKNK1 | NR1I2 | SLC41A1 | Reverse transcriptase (Telomerase) | GFER | HDAC5 | GRM6 | HCRTR1 | MS4A6A | ERCC2 | LRRK1 | Small Conductance Calcium-Activated Potassium Channel (SK) (nonspecified subtype) | SORT1 | Opioid receptor (nonspecified subtype) | beta-Secretase (nonspecified subtype) | FHIT | KCNK2 | MECP2 | NOX4 | TET2 | Guanylate cyclase (nonspecified subtype) | GM-CSF Receptor (GM-CSF-R) | YWHAG | Casein kinase I (nonspecified subtype) | PDE5A | GRIN2D | GRM2 | GSTO1 | USP19 | HSF1 | NDUFS8 | PDGFRA | LOC105373629 | RYR2 | PGAM5-KEAP1-NRF2 Complex | TRAF6 | OPRD1 | ATG16L1 | TRIM41 | ADRA2A | MAP3K11 | VCAM1 | XPO1 | Mitogen-Activated Protein Kinase (nonspecified subtype) | EIF2AK2 | ATG5 | TWNK | SMPD1 | Peroxisome Proliferator-Activated Receptors (PPAR) (nonspecified subtype) | TGM2 | KYNU | ATP5IF1 | DLG1 | G4137 | MTNR1B | VIP | ATP10B | DNM1L | IRAK4 | STX6 | GPX1 | Chaperone (nonspecified subtype) | JAK2 | NMDA receptor | PTRHD1 | G5595 | GPR3 | RPS6KB1 | KIT | GRIN2A | CES1 | SLC6A9 | SLC19A1 | PICALM | TLR9 | TRIM10 | Nicotinic alpha4beta2 receptor | Chloride channel (nonspecified subtype) | DNMT3B | DRD5 | GSTP1 | BALR6 | RARB | CLU | TAF15 | DNAJC10 | ANK1 | LOC105369302 | RCOR1 | SYN3 | PODXL | Nicotinic alpha3beta4 Receptor | SKP1 | G2033 | USP24 | NR4A1 | BST1 | XRCC3 | CCNT1 | HLA-DRA | G673 | EIF4E | GALNT2 | ASH1L | HLA-DOB | Platelet-Derived Growth Factor Receptor (nonspecified subtype) | ADORA3 | LOC105373759 | Histone acetyltransferase (HAT) (nonspecified subtype) | ADRB1 | TF | ACSL4 | P2RY6 | TRIM6 | Adenylate Cyclase (nonspecified subtype) | YWHAZ | OPRL1 | GCKR | ITK | ATXN3 | ND2 | GIPR | GRM7 | CACNG8 | NADH dehydrogenase (Complex I) | SGK2 | FTMT | CHRM3 | ARHGAP39 | TRPA1 | USP14 | IMPDH1 | CSMD1 | KCNA5 | VIPR1 | Calcium-Activated K(Ca) Potassium Channel (nonspecified subtype) | alpha-Secretase (nonspecified subtype) | CTSG | EPHA3 | LOC105371114 | PLEKHM1 | Casein kinase II (CKII) | IFNG | TSPO | FAAH | CCDC62 | CHRNA9 | MAPKAPK2 | CDK8/Cyclin C | VHL | CAST | POLG | RIT2 | IL2 | COL9A2 | NEK7 | UQCRC1 | NOS2 | ABCA4 | PARP11 | CHRNA2 | IL1A | DLG2 | PANX1 | TUBA3E | JAK1 | DRD1 | NUDT1 | STH | CERS6 | HIP1 | ANO3 | VASH1 | CCND3 | FKBP5 | GBF1 | FAM47E-STBD1 | EIF2B3 | PRMT1 | ADRB2 | UBE2N | NEDD4 | PBX2 | TET1 | TAS1R2 | 15-Lipoxygenase (nonspecified subtype) | EIF2AK4 | MIR133B | SSTR4 | UQCRH | DDR1 | GABRA1 | FBXO7 | LINGO1 | JAK3 | SLC1A6 | FASN | STK32B | FERMT2 | G114548 | P2RY12 | C1QC | ATG12 | LOC105373937 | MAP4K4 | SCN9A | ABCC8 | G7099 | GABRB3 | TAS2R19 | AADACL2-AS1 | MAPK9 | TBP | MAPT-AS1 | FFAR2 | SNX6 | Amyloid beta A4 precursor protein-binding family (APP-BP) (nonspecified subtype) | CYP2R1 | GSTM1 | PRKCD | HRH1 | P2RY13 | Proteasome Complex | ASIC2 | EIF4G1 | FABP3 | PTK2B | AAK1 | PLXNA4 | ROCK2 | NLRP3 Inflammasome | Eukaryotic Translation Initiation Factor 4A (eIF-4A) | Histone deacetylase (nonspecified subtype) | CALB1 | TUBB6 | Heme Oxygenase (HO) (nonspecified subtype) | Glycogen synthase kinase 3 (GSK-3) (nonspecified subtype) | PAOX | BMP2K | BLK | Serine protease (nonspecified subtype) | ERBB4 | NOX3 | UGT1A9 | ABCC9 | PYCARD | VPS26A | CFTR | HDAC4 | MAP4K1 | CCR5 | Trypsin (nonspecified subtype) | KDM1A | CCDC82 | PLA2G6 | LOC100507053 | GUSB | LOC105374187 | EPHB6 | DYRK3 | TREM2 | PHF2 | GAA | CCNE1 | HCRTR2 | Complement Complex | MPG | MFN2 | SCN1A | G196 | EIF4G2 | ND3 | TRIM28 | BIN3 | APOE | CDK4/Cyclin D | LDLRAD3 | KCNQ1 | DLG4 | FDPS | NFKBIB | HEXA | RINL | CDK1/Cyclin B | MAP3K7 | CAPN1 | LILRB3 | PTPN11 | CREBBP | OGN | LOC105371449 | G3576 | PINK1 | L-Type calcium channel (nonspecified subtype) | ALDH1A1 | G5133 | Phospholipase A2, Cytosolic (nonspecified subtype) | EYS | Caspase (nonspecified subtype) | PRL | AHSA1 | ABHD6 | AP-1 Transcription Factor Complex | CA2 | SLC6A11 | SNX1 | LYN | G1786 | QPCT | LCP2 | TACR1 | VIPR2 | SIK2 | MAP2K2 | CSNK1A1 | TYMS | TRIM24 | NADSYN1 | GRM8 | CHRNA3 | C1QA | FOLH1 | BACE1 | SLC45A3 | PLA2G4C | CDKN1B | HLA-DQB1 | sigma Receptor (nonspecified subtype) | NTSR1 | PDE2A | UGT1A1 | GRIK3 | LINC02210-CRHR1 | CRHR1 | Heat shock protein 70 (nonspecified subtype) | SPANXD | MALAT1 | LMNA | NUBPL | PON1 | RXRA | LOC105369732 | HSPA9 | NUS1 | PRAG1 | ABL1 | FCGBP | HTR1B | CDK2/Cyclin A | ADRA1D | FPR2 | FAM47E | APEX1 | Dopamine receptor (nonspecified subtype) | CYP19A1 | Poly [ADP-ribose] polymerase (nonspecified subtype) | MIF | APOA1-AS | HTR6 | alpha1-Adrenoceptor (nonspecified subtype) | EPX | 5-Hydroxytryptamine Receptor 2 (5-HT2) (nonspecified subtype) | TPH1 | TXNRD1 | NSF | CACNA1D | SNCAIP | Potassium Channels (nonspecified subtype) | EPHA2 | LOC100287944 | PARP2 | Muscarinic Acetylcholine Receptor (mAChR) (nonspecified subtype) | PDE1B | PKM | NUAK1 | HTR2C | TRIM27 | Cyclin D (nonspecified subtype) | NADPH Oxidase Complex | CYP2J2 | EPOR | C3 | IGSF9B | LOC105369736 | PSAP | SORCS2 | CLRN3 | CR1 | Integrin alphaLbeta2 (LFA-1) receptor | FRK | Nitric oxide synthase (NOS) (nonspecified subtype) | LRRC4 | NAGLU | OGA | FBXO41 | SLC5A1 | ND4 | MYLK | S1PR5 | SLC40A1 | CD33 | SLC17A1 | AGER | TRIM6-TRIM34 | CACNA1A | ROR1 | FTO | ELAVL4 | TREM1 | WDR12 | APP | VCP | PDE4C | RBM28 | UBTD2 | GPR55 | NPEPPS | SCN5A | DRD3 | TH | GABRA5 | SLC6A3 | MIR4697 | LOC105371701 | HLA-C | Cyclooxygenase (COX) (nonspecified subtype) | CYP26A1 | LDHA | ATP6 | CA9 | NAMPT | LOC105371702 | DNAJC6 | ADCYAP1R1 | XRCC1 | TMEM97 | GLP1R | B3GALT1-AS1 | PTPRN2 | IFIH1 | Cannabinoid receptor (nonspecified subtype) | ACP2 | MIR4448 | SCARB2 | CLK1 | DCTN1 | UCHL1 | CHCHD2 | ALOX5 | PIK3CG | TGM5 | CYP26B1 | APOA1 | IL13 | TRPM2 | GRM3 | STING1 | G6774 | TDO2 | P2RX7 | FYN | G3082 | Adenosine receptor (nonspecified subtype) | B3GALT1 | GRM1 | ACACB | PDGFRB | GAK | CHEK2 | GBA3 | CNTN1 | FUS | ANG | MAPK10 | Peptidylprolyl Isomerase (nonspecified subtype) | MAOB | C5AR1 | SLC11A2 | PIN1 | ATN1 | SERPINA1 | GPX4 | G3146 | ZNF512B | Fibroblast Growth Factor Receptor (FGFR) (nonspecified subtype) | SIK1 | NT5E | DOT1L | PTBP2 | CCL2 | IL16 | NOL7 | CCKAR | TNK2 | CLN5 | CSF1R | MTR | GPR6 | SMPD3 | CHRM5 | ADH5 | ASIC1 | ERN1 | MRI1 | Voltage-Gated Calcium Channel alpha-2/delta (nonspecified subtype) | CDK6/Cyclin D3 | ERAP1 | CARMIL1 | HK2 | Large Conductance BK(Ca) Potassium Channel (Maxi K+ Channel) (nonspecified subtype) | NADPH Oxidase (nonspecified subtype) | SLC6A1 | NQO2 | GABRD | KL | KRR1 | AMP-activated protein kinase (AMPK) | DYRK1B | HLA-DRB1 | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 (nonspecified protein) | NQO1 | P2RX2 | ADP/ATP Translocase (nonspecified subtype) | beta-Hexosaminidase Complex | NUMA1 | OPRM1 | SIRT5 | CASP1 | USP30 | NOX1 | HMOX1 | FAF1 | G2475 | PLA2G2D | HTT | Cyclin A (nonspecified subtype) | Soluble guanylyl cyclase | SMN1 | PLA2G7 | BRIP1 | TRIM9 | RIPK1 | BCKDK | PSMB8 | AKR1B10 | CDK1 | AKT3 | GLP2R | RBM39 | Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase (SERCA) (nonspecified subtype) | 5-Hydroxytryptamine Receptor (nonspecified subtype) | PDE4A | ATXN1 | GABRA2 | F2RL3 | ND4L | TRIM11 | CPNE1 | HIF1A | LOC107984782 | SETD1A | Phospholipase A2, Secretory (sPLA2) (nonspecified subtype) | CTSB | SLC22A5 | SPPL2C | HDAC6 | GRIN2B | PGLYRP2 | Rho kinase (ROCK) (nonspecified subtype) | BTK | MMP1 | SEMA3A | MFSD3 | CDK2/Cyclin E | Nicotinic alpha4beta4 receptor | AKAIN1 | TCF7L2 | ICMT | EIF4G3 | S100B | KCNH1 | SLC6A13 | XIST | PDE7B | EIF2AK3 | Phosphodiesterase 8 (nonspecified subtype) | KCNJ8 | SCD5 | STX1B | ALDOC | PGLYRP3 | SNORD63 | SLC2A9 | Cyclin-dependent kinase inhibitor (nonspecified subtype) | ZNF519 | Mitogen-activated protein kinase p38 (MAPK p38) (nonspecified subtype) | THOP1 | BAP1 | Transglutaminase (nonspecified subtype) | G1956 | ELANE | CISD1 | HLA-DRB4 | RIPK3 | CHRNA4 | STX1A | MTHFR | G4780 | G5243 | MIR4519 | Fructose-Bisphosphate Aldolase (nonspecified subtype) | CHRM2 | GBA2 | RAB5A | ND5 | NTRK2 | ANK2 | GRM4 | HDAC2 | Retinoid RXR receptor (nonspecified subtype) | HCAR2 | CNR2 | Dual Specificity Mitogen-Activated Protein Kinase Kinase (MEK) (nonspecified subtype) | PRKN | LOXL3 | MPO | TRNL1 | FGF2 | CDK7 | LZTS3 | IGF2 | CDK7/Cyclin H | G6647 | TAP1 | SERPING1 | UBA6 | CHRNB2 | TCEANC2 | COL6A3 | G6714 | DRD2 | RIC3 | SIRT4 | PDE4D | NAAA | ANXA1 | alpha-6 beta-2 Nicotinic receptor | Nicotinic alpha9alpha10 Receptor | CX3CR1 | SMN2 | HSD3B7 | PIK3CA | TENM4 | PNLIP | RASAL3 | CACNB4 | WLS | FOXD3-AS1 | PRKACA | PARK7 | NR4A2 | DNM3 | IGF2BP2 | HLA-B | PPARGC1A | G5347 | PPARG | PRKCE | ENOX2 | ACACA | CSNK1D | PTPRC | BDNF | SLC30A8 | FRAS1 | STK39 | CHRNA6 | Neurotensin receptor (nonspecified subtype) | SORL1 | FABP4 | OPRK1 | GRN | Calcium/calmodulin-dependent protein kinase type II (CaMK-II) | Imidazoline I2 receptor (I2) | G3620 | Mitogen-activated protein kinase (JNK) (nonspecified subtype) | Phosphodiesterase IV (PDE4) (nonspecified subtype) | ABAT | SIRT3 | UTP25 | Phosphodiesterase (nonspecified subtype) | HIVEP3 | Glutamate Receptor Ionotropic AMPA Receptor | USP7 | AOC3 | PRKG1 | Superoxide dismutase (SOD) (nonspecified subtype) | Nicotinic alpha6beta2beta3 receptor | ITPKB | BRCA2 | G8878 | CACNA1I | HLA-DRB5 | Nicotinic alpha6alpha3beta2beta3 receptor | MC1R | LOC107985250 | ATXN2 | KCNN1 | DNAJC7 | NGF | ODC1 | CAMKK1 | CDK4 | CDK6 | TMC3 | RORC | TAAR1 | CASP6 | RAB39B | IDE | ARSA | EEF1D | G207 | ALOX15 | PPP1R15B | VPS13C | GPR39 | BCL7C | PTGER2 | HRH3 | SCN2A | Neuronal acetylcholine receptor alpha2beta2 receptor | SLC1A2 | ADRA2C | TLR3 | PDE1A | PPARA | CDK2 | CPLX1 | HTR7 | A2M | DYRK2 | ERCC5 | TTPA | DCC | LDLR | STXBP1 | MCCC1 | HTR1D | PGK1 | Nicotinic alpha3beta2 receptor | Calcium channel (nonspecified subtype) | TRNC | NNMT | GPR65 | DNA Methyltransferase (DNMT) (nonspecified subtype) | ANKRD24 | Neuronal acetylcholine receptor alpha2beta2 receptor | TAP2 | TYK2 | SYT11 | PON2 | LRRK2 | Glutamate Receptor Ionotropic (nonspecified subtype) | Major histocompatibility complex class II antigens (nonspecified subtype) | Heat shock protein 90 (nonspecified subtype) | CYBA | NLN | KDM5A | COMT | 5-Hydroxytryptamine Receptor 3 (5-HT3 receptor) (nonspecified subtype) | TBXAS1 | TRPM3 | GCGR | GPR17 | SNCA | LRP4 | GALC | RNF11 | G142 | Tubulin | TOP1 | PRMT3 | mu-Calpain (calpain 1) | GABRA3 | L3MBTL1 | PARL | PGLYRP4 | SHMT1 | GPBAR1 | G2099 | FGL1 | YES1 | PARG | MIR4761 | PRNP | CLOCK | CNR1 | CP | G7124 | TRPM8 | HCK | Na+/Ca2+ Exchanger (NCX) (nonspecified subtype) | KCNN2 | COX1 | FGF20 | RIPK2 | CHRNA5 | SMO | G5743 | Protein kinase C (nonspecified subtype) | FADS1 | PDE7A | Ryanodine receptor (nonspecified subtype) | CCDC60 | TRPV1 | PIK3CD | COQ2 | Monoamine oxidase (MAO) (nonspecified subtype) | CACNA1H | Nicotinic alpha3beta2beta3 receptor | KCNJ11 | SIRT6 | SLC6A2 | TOR1A | NOTCH3 | CAPN2 | ADAR | Protein Kinase B (PKB/Akt) (nonspecified subtype) | CSK | ULK1 | CCNK | CYP46A1 | CHRNA1 | TRIM40 | PLA2G2A | GHSR | G3569 | CTSD | MAOA | PDE4B | PLCG2 | GPR35 | HFE | L-type voltage-dependent calcium channel complex | CFB | TACR3 | CACNA1B | MIR548AT | RGS4 | CASC16 | LINC02210 | KDR | TFRC | CGAS | CCR3 | RYR1 | MAP2K4 | CSNK1E | SREBF1 | G4233 | FGR | DDR2 | GPR143 | ABL2 | KAT2B | MFN1 | G5599 | PILRA | HDAC1 | HLA-DQA1 | SNCA-AS1 | C5 | GOLGA4 | SV2A | HTR1A | Protein Phosphatase 2A | Vasoactive intestinal polypeptide receptor (VIP-R) (nonspecified subtype) | DDC | ACHE | KMO | RAB29 | GSK3A | G9429 | Eukaryotic translation initiation factor 2B | Alpha-2 Adrenergic receptors (nonspecified subtype) | KCND2 | LINGO2 | EPHX2 | ESR2 | TTR | TRIM8 | Cyclin B (nonspecified subtype) | DNAJC13 | GIGYF2 | G3630 | FGFR1 | SIRT2 | NT5C2 | C19orf12 | GDNF | CD36 | PTGS1 | TAS1R3 | SYT12 | GRM5 | GSR | SLC22A11 | GABA(A) receptor | MPHOSPH10 | PREP | MAP2K1 | IL2RA | FKBP1A | CASP7 | PER2 | HNMT | CSF3 | SH3GL2 | CCK receptor (nonspecified subtype) | TACR2 | KDM5A-GATAD1-EMSY chromatin complex | SLC22A1 | MIR30A | G1026 | SPPL2B | VDR | ADAM10 | MYLIP | PTGES | SLC18A2 | DGKQ | COX2 | AXL | LOC105379193 | G3320 | SLC2A13 | P2X2/3 Receptor Complex | gamma-Secretase | TRPC4 | ITPR2 | GBA1 | Amino acid hydroxylase (nonspecified subtype) | CYP2D6 | Kainate Receptor (GluR) (nonspecified subtype) | IDH1 | Voltage-Gated Sodium Channel Complex | SLC9A1 | ALDH2 | INPP5F | PADI4 | MIR762HG | TOMM40 | COL1A1 | MUC17 | KANSL1 | HMGCR | IL1B | ATXN7 | Sodium channel (nonspecified subtype) | NOS1 | G23411 | ZBTB38 | WASL | MKNK2 | SIGMAR1 | PSEN1 | Diacylglycerol Acyltransferase (DGAT) (nonspecified subtype) | ROCK1 | MFSD4A | KCNN3 | MAP3K12 | CDK5R1 | CHRM4 | CHRNB3 | MLKL | VTRNA2-1 | ACTR3B | GPR139 | G1432 | Metabotropic glutamate (mGluR) receptor (nonspecified subtype) | G4318 | TYR | TARDBP | LRP10 | PITX3

疾病靶点研报
Parkinson's Disease

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Behavioral Variant Of Frontotemporal Dementia | Urolithiasis | Dermatomyositis | Glioblastoma | Demyelinating Diseases | Hereditary Elliptocytosis | Thrombophlebitis | Paget's Disease Of The Breast | Hidradenitis | Spinocerebellar Ataxia Type 31 | Heroin Dependence | Episodic Ataxia Type 2 | Atelosteogenesis Type 2 | Sertoli Cell-only Syndrome | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Hypotension, Orthostatic | Growth Hormone Excess | Antisynthetase Syndrome | Protein S Deficiency | Vitreoretinal Degeneration, Snowflake Type | Chronic Neutrophilic Leukemia | Cerebrotendinous Xanthomatosis | Chylomicron Retention Disease | Spinocerebellar Ataxia Type 15 | Renal Failure | Saul-Wilson Syndrome | Aneurysm, Abdominal Aortic | Duodenal Atresia | GLUT1 Deficiency Syndrome | Dubin-Johnson Syndrome | Oculocutaneous Albinism Type 4 | Osteochondrosis | Diffuse Intrinsic Pontine Glioma | Glomerulonephritis, Membranoproliferative | Charcot-Marie-Tooth Disease Type 4 | Camurati-Engelmann Disease | Atopic Dermatitis | Cerebrovascular Disorders | Anemia | Proopiomelanocortin Deficiency | Eccrine Porocarcinoma | Cancer, Breast | Focal Cortical Dysplasia Type 2 | Congenital Heart Block | Hyperinsulinemia | Borderline Personality Disorder | Glutaric Aciduria Type 3 | Imerslund-Grasbeck Syndrome | Kearns-Sayre Syndrome | Gnathodiaphyseal Dysplasia | Mitochondrial DNA Depletion Syndrome 13 | Keratoconjunctivitis | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Chorioretinitis | Ocular Surface Squamous Neoplasia | Bulimia Nervosa | Arterial Tortuosity Syndrome | Congenital Disorders Of Glycosylation Type II | Nail-Patella Syndrome | Osteogenesis Imperfecta Type VI | Facioscapulohumeral Muscular Dystrophy Type 1 | WAGR Syndrome | CEDNIK Syndrome | Delayed Sleep Phase Syndrome | Peeling Skin Syndrome, Acral Type | Epidermolysis Bullosa Acquisita | Canavan Disease | Hyperkeratosis | Hyperparathyroidism | Hyperostosis | Sjogren Syndrome | Porphyria, Variegate | Vertebrobasilar Insufficiency | Keratosis, Actinic | Spinocerebellar Ataxia Type 14 | Hyperbilirubinemia | Meningitis | Hypercholesterolemia, Familial | Kawasaki Disease | Lupus Erythematosus | Smoldering Myeloma | Genee-Wiedemann Syndrome | Transcobalamin Deficiency | Atopy | Anorectal Malformations | Shprintzen-Goldberg Syndrome | Headache | Hydronephrosis | Alopecia Totalis | Cryptococcal Meningitis | Papillorenal Syndrome | Microphthalmia | Epithelial-myoepithelial Carcinoma | Pneumonia, Bacterial | Posterior Polar Cataract | Inflammatory Myofibroblastic Tumor | Pfeiffer Syndrome | Pantothenate Kinase-associated Neurodegeneration | Pyelonephritis | Autosomal Recessive Bestrophinopathy | Hemophilia | SAPHO Syndrome | 3-methylglutaconic Aciduria Type I | Myofibromatosis | Motor Neuron Diseases | Acrocallosal Syndrome | Dysmorphophobia | Lyme Disease | Campomelic Dysplasia | Coronary Artery Disease | Donnai-Barrow Syndrome | Diarrhea | Keratosis, Seborrheic | Dystrophy, Cone-rod | Hypogonadism | Goiter | Intestinal Tuberculosis | Nestor-Guillermo Progeria Syndrome | Gastric Atrophy | Temtamy Preaxial Brachydactyly Syndrome | Agnathia-Otocephaly Complex | Moyamoya Disease | Knobloch Syndrome | Neurodegeneration With Brain Iron Accumulation | Cardiomyopathy, Hypertrophic | Erythema Nodosum | Hyperparathyroidism, Secondary | Anthrax | Ectodermal Dysplasia | Corneal Neovascularization | Pityriasis Rubra Pilaris | Bronchitis, Chronic | Tardive Dyskinesia | Malaria | Intestinal Pseudo-obstruction | Photosensitivity | Metaphyseal Chondrodysplasia, Schmid Type | Contact Dermatitis | Heart Septal Defects | Pseudohypoparathyroidism Type 2 | Hydrops Fetalis | Rhinitis | Primary Hyperoxaluria | Thalassemia, Beta | Zygomycosis | Primary Torsion Dystonia | Ureteropelvic Junction Obstruction | Rett Syndrome | Fibronectin Glomerulopathy | Glycogen Storage Disease Type 9 | Wolcott-Rallison Syndrome | Myoclonic Atonic Epilepsy | Hypertension | Hidradenitis Suppurativa | Astigmatism | Personality Disorders | Cleidocranial Dysplasia | Pregnancy, Ectopic | Phenylketonuria | 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Spinal Muscular Atrophy Type 3 | Meconium Ileus | Carcinoma, Small Cell | Benign Recurrent Intrahepatic Cholestasis 1 | Muir-Torre Syndrome | Thrombocytopenia | Familial Male-limited Precocious Puberty | Scapuloperoneal Spinal Muscular Atrophy | Multisystemic Smooth Muscle Dysfunction Syndrome | Spinocerebellar Ataxia Type 6 | Leukoplakia | Hypertriglyceridemia | Achondrogenesis | Melanoma | Cardiomyopathy, Peripartum | Persistent Fetal Circulation | Esophagitis, Eosinophilic | Pulmonary Stenosis | Hypohidrotic Ectodermal Dysplasia | Familial Digital Arthropathy-brachydactyly | Antisocial Personality Disorder | Non-small Cell Lung Cancer | Angelman Syndrome | Prolymphocytic Leukemia | Familial Exudative Vitreoretinopathy | Esophageal Adenocarcinoma | Pterygium | Congenital Hereditary Endothelial Dystrophy Type II | Arthritis, Gouty | Tyrosinemia | Pontocerebellar Hypoplasia | Tinea | Polyneuropathy | Benign Familial Neonatal Convulsions | Zimmermann-Laband Syndrome | Acute Lymphocytic Leukemia | Thin Basement Membrane Disease | Superficial Spreading Melanoma | Persistent Truncus Arteriosus | Optic Atrophy 2 | Amelanotic Melanoma | Syncope | Familial Dysautonomia | Acromesomelic Dysplasia | Lymphoma, Mantle Cell | Corneal Dystrophy And Perceptive Deafness | Agoraphobia | Impetigo | Liddle Syndrome | T-cell Chronic Lymphocytic Leukemia | Narcolepsy | Pheochromocytoma | Cluster Headache | Cerebellar Ataxia, Cayman Type | Spondylometaphyseal Dysplasia | Pericarditis | Methemoglobinemia | Early Infantile Epileptic Encephalopathy 13 | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Palmoplantar Keratoderma | Homocystinuria | Multiple Sclerosis, Primary Progressive | Wolfram Syndrome | Thrombocythemia, Essential | Mitochondrial Cytopathy | Hyperbilirubinemia, Neonatal | Rift Valley Fever | Sclerocornea | POEMS Syndrome | Sialoadenitis | Esophageal Motility Disorders | Medulloblastoma | Peters-plus Syndrome | Klinefelter Syndrome | Fuchs Heterochromic Iridocyclitis | Hepatitis A | Lung Diseases | Mandibuloacral Dysplasia With Type A Lipodystrophy | Bursitis | Creatine Deficiency Syndrome Due To AGAT Deficiency | Acromicric Dysplasia | Porphyria | Congenital Adrenal Hyperplasia 1 | Skin Carcinoma | Familial Hemiplegic Migraine | Swine Influenza | Congenital Dyserythropoietic Anemia Type 1 | Panic Disorder | Amblyopia | Chordoma | Alpha-thalassemia Myelodysplasia Syndrome | Dystonia | Cantu Syndrome | Congenital Bilateral Absence Of Vas Deferens | Hypobetalipoproteinemias | HANAC Syndrome | Liver Failure | Waardenburg Syndrome Type 4 | Norrie Disease | Hypothalamic Obesity | Chitayat Syndrome | Pelvic Inflammatory Disease | Pupil Disorders | Lymphoma, AIDS-related | Diabetes Gestational | Sclerosteosis 2 | Sarcomatoid Carcinoma Of The Lung | Pulmonary Sclerosing Hemangioma | Spinal Muscular Atrophy | Polycystic Ovary Syndrome | Erdheim-Chester Disease | Whipple's Disease | Osmotic Demyelination Syndrome | Communication Disorders | Facioscapulohumeral Muscular Dystrophy | Huntington's Disease-like 2 | Dentinogenesis Imperfecta | Acute Chest Syndrome | Primary Ovarian Insufficiency | Leukoencephalopathy, Progressive Multifocal | Vascular Cognitive Impairment | Mitochondrial Encephalomyopathy | Asthma, Nocturnal | Tibial Muscular Dystrophy | Purpura | Torticollis | NDH Syndrome | Basal Ganglia Disease | Microcephaly, Seizures, And Developmental Delay | Hemolytic Uremic Syndrome | Parapsoriasis | Pyruvate Carboxylase Deficiency Disease | Zollinger-Ellison Syndrome | Leiomyosarcoma | Relapsing Polychondritis | Cabezas Syndrome | Paronychia | Cutaneous Angiosarcoma | Ovarian Sex Cord-stromal Tumor | Rhabdomyosarcoma | Brachydactyly | Alcoholism | Sclerosing Cholangitis | Goiter, Nodular | Angiodysplasia | Paraganglioma, Carotid Body | Primary Aldosteronism | Renal Tubular Dysgenesis | Aplastic Anemia | Milk Allergy | DICER1 Syndrome | Blomstrand Osteochondrodysplasia | Lipoma | Polymyalgia Rheumatica | Neuromyotonia | Neurofibromatosis Type 2 | Hereditary Mixed Polyposis Syndrome | Hereditary Coproporphyria