Disease

Heart Septal Defects

About the Disease
Heart Septal Defect, also known as heart septal defects, is related to atrial septal defect 2 and atrial septal defect 5. An important gene associated with Heart Septal Defect is NKX2-5 (NK2 Homeobox 5), and among its related pathways/superpathways are Human Embryonic Stem Cell Pluripotency and 22q11.2 copy number variation syndrome. The drugs Acetylsalicylic acid and Clopidogrel have been mentioned in the context of this disorder. Affiliated tissues include heart, lung and endothelial, and related phenotypes are normal and muscle

Common Targets
ATIC | GART | MTHFD1 | FIGN | SHMT1

疾病靶点研报
Heart Septal Defects

Note: If you'd like to get a target analysis report for Heart Septal Defects, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Heart Septal Defects at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Cerebellar Ataxia, Cayman Type | Nephronophthisis | Erdheim-Chester Disease | Chronic Inflammatory Demyelinating Polyneuropathy | Mesothelioma, Malignant | Membranous Nephropathy | Cockayne Syndrome | Acne Vulgaris | Congenital Generalized Lipodystrophy | Myoclonic Atonic Epilepsy | Hemolytic Uremic Syndrome, Atypical | Sertoli Cell-only Syndrome | Vitreoretinopathy, Proliferative | Lattice Corneal Dystrophy Type 1 | Osteonecrosis Of The Jaw | Lipid Metabolism Disorders | VACTERL Association | Choroideremia | Congenital Tufting Enteropathy | Cutaneous Lupus Erythematosus | Coffin-Siris Syndrome | Acute Lymphocytic Leukemia | Pemphigoid | X-linked Acrogigantism | Cushing Syndrome | Bronchitis | Hyperprolactinemia | Malonyl-CoA Decarboxylase Deficiency | Familial Cerebral Amyloid Angiopathy | Metabolic Syndrome | CDKL5 Deficiency Disorder | Otitis Media | Arterial Tortuosity Syndrome | Nicotine Dependence | Sitosterolemia | Exostoses | Uremia | Thrombocythemia, Essential | Amyotrophic Lateral Sclerosis | Spinocerebellar Ataxia Type 38 | Autism | Neurotoxicity | PASLI Disease | Granuloma Annulare | Familial Digital Arthropathy-brachydactyly | Congenital Aniridia | Sjogren Syndrome | Fibronectin Glomerulopathy | Imerslund-Grasbeck Syndrome | Cramp Fasciculation Syndrome | Posterior Polar Cataract | Autoimmune Disease | Corneal Edema | Myasthenia | Cholestasis, Intrahepatic | Saethre-Chotzen Syndrome | Hyperandrogenemia | Progressive Myoclonic Epilepsy | PHARC Syndrome | Hypopituitarism | Hyperthyroidism | Heterotaxy | Ovarian Hyperstimulation Syndrome | Focal Dermal Hypoplasia | Huntington's Disease | Asthma | Dysthymia | Measles | Schizencephaly | Low Phospholipid Associated Cholelithiasis | Hypotrichosis | Waardenburg Syndrome | Primary Cutaneous Amyloidosis | Mitochondrial Myopathy | Fabry's Disease | Ocular Hypertension | Meningococcal Meningitis | Lysosomal Acid Lipase Deficiency | Tietze Syndrome | Carotid Artery Disease | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Arteriosclerosis | Dysmorphophobia | Muir-Torre Syndrome | Demyelinating Diseases | Branchiootorenal Syndrome | Gastroenteritis, Eosinophilic | Eosinophilia | Impulse Control Disorder | Pleomorphic Xanthoastrocytoma | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Vertigo | Coma | Acral Lentiginous Melanoma | Xeroderma Pigmentosum Variant Type | HELLP Syndrome | Hereditary Sensory And Autonomic Neuropathy | Platelet Disorders | Papillorenal Syndrome | Infantile Refsum Disease | Chondrodysplasia Punctata | Ectodermal Dysplasia | Partington Syndrome | Leishmaniasis, Cutaneous | Nephroblastoma | Thin Basement Membrane Disease | Histoplasmosis | Multiple Sclerosis, Secondary Progressive | Triple A Syndrome | Blomstrand Osteochondrodysplasia | Myositis | Mountain Sickness | DOCK8 Immunodeficiency Syndrome | Pupil Disorders | Vertebrobasilar Insufficiency | Cutaneous Angiosarcoma | Familial Hypobetalipoproteinemia | Early Infantile Epileptic Encephalopathy 1 | Purpura | Congestive Heart Failure | Gitelman Syndrome | Conjunctivitis | Chitayat Syndrome | Hyperoxaluria | Congenital Adrenal Hyperplasia 1 | Asthma, Exercise-induced | Esophageal Adenocarcinoma | Zollinger-Ellison Syndrome | Optic Neuropathy | Sarcoidosis | Poikiloderma With Neutropenia | 3C Syndrome | Fascioliasis | Borjeson-Forssman-Lehmann Syndrome | Focal Cortical Dysplasia Type 2 | Hemochromatosis Type 2 | Phenylketonuria II | Cerebral Cavernous Malformations | Aplasia Cutis Congenita | Congenital Heart Block | Microphthalmia, Syndromic 7 | Eating Disorder | Thyroiditis, Autoimmune | Stroke, Ischemic | Fetal Akinesia Deformation Sequence | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Tinea Versicolor | Multiple Sclerosis, Primary Progressive | Primary Hyperoxaluria Type 3 | Cerebrotendinous Xanthomatosis | Hypertension, Portal | Hemophagocytic Lymphohistiocytosis | Mucolipidosis Type II | Papilloma | Erythrokeratodermia Variabilis | Delayed Sleep Phase Syndrome | Cerebellofaciodental Syndrome | Cerebral Amyloid Angiopathy | Basal Ganglia Cerebrovascular Disease | Sotos Syndrome | Avian Influenza | Spinocerebellar Ataxia Type 3 | AIDS Dementia Complex | Shwachman-Bodian-Diamond Syndrome | Microcephalic Primordial Dwarfism | Joubert Syndrome | Autism Spectrum Disorders | X-linked Sideroblastic Anemia | Meningioma, Benign | Vici Syndrome | Inflammatory Joint Disease | Exotropia | Acromicric Dysplasia | Kohlschutter-Tonz Syndrome | Esophageal Motility Disorders | Diffuse Intrinsic Pontine Glioma | Blepharospasm | Rash | Mitochondrial Disease | Bainbridge-Ropers Syndrome | Tay-Sachs Disease | Androgenic Alopecia | Ameloblastoma | Spina Bifida | Congenital Central Hypoventilation Syndrome | Kallmann Syndrome | Reticular Dysgenesis | Cystinosis | Apparent Mineralocorticoid Excess Syndrome | Lymphoproliferative Disease, X-linked | Hypophosphatemic Rickets With Hypercalciuria, Hereditary | Tonsillitis | Allan-Herndon-Dudley Syndrome | Anovulation | Creutzfeldt-Jakob Disease | Leber Hereditary Optic Neuropathy | Sulfite Oxidase Deficiency | Colon Adenoma | Multiple System Atrophy | Smith-Lemli-Opitz Syndrome | Niemann-Pick Disease | Thromboembolism | Proteasome-associated Autoinflammatory Syndrome 2 | Glaucomatocyclitic Crisis | Cystitis, Interstitial | Glutaric Aciduria Type 2 | IgA Deficiency | Bartter Syndrome | Polycystic Liver | Inflammatory Linear Verrucous Epidermal Nevus | Aspergillosis | Sporadic Hemiplegic Migraine | Absence Epilepsy | Adrenoleukodystrophy, X-linked | Osteogenesis Imperfecta | Leigh Syndrome | Combined Pituitary Hormone Deficiency | Conn Syndrome | Ichthyosis Bullosa Of Siemens | VEXAS Syndrome | Vogt-Koyanagi-Harada Syndrome | Leukoplakia, Oral | Myasthenia Gravis | Peutz-Jeghers Syndrome | Diverticulitis | Primary Hyperoxaluria | Mucolipidosis Type III | Cryopyrin-associated Periodic Syndromes | Alpha-1 Antitrypsin Deficiency | Infertility | Charcot-Marie-Tooth Disease, Type 2 | Paraplegia | Alagille Syndrome | Polyneuropathy | Hypoparathyroidism | Veno-occlusive Disease | IgA Nephropathy | Reye Syndrome | Restless Legs Syndrome | Hereditary Spherocytosis | Osteoporosis, Postmenopausal | Optic Neuropathy, Anterior Ischemic | Chronic Lymphocytic Leukemia | Hypertension, Pulmonary | Bronchiolitis | Hemoglobinopathies | Bardet-Biedl Syndrome | Prune Belly Syndrome | Diffuse Mesangial Sclerosis | Autosomal Recessive Spastic Paraplegia Type 75 | Mohr-Tranebjaerg Syndrome | Methemoglobinemia Type IV | Occipital Neuralgia | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Pemphigus Foliaceus | Hypogammaglobulinemia | Periodontitis | Adenosine Deaminase 2 Deficiency | Angiosarcoma | Vitamin K Deficiency | Fukuyama Congenital Muscular Dystrophy | Pain | Aarskog-Scott Syndrome | Autosomal Recessive Bestrophinopathy | Generalized Epilepsy With Febrile Seizures Plus | Coronary Restenosis | Diabetes | Glycogen Storage Disease | Pyruvate Carboxylase Deficiency Disease | Ectrodactyly | Teratozoospermia | FG Syndrome | Thalassemia, Beta | Intestinal Tuberculosis | Peritonitis | Hemochromatosis | Stiff-man Syndrome | Colitis, Collagenous | Hepatic Veno-occlusive Disease | Keratopathy | Dysequilibrium Syndrome | Infantile Spasm | Polycystic Kidney, Autosomal Dominant | Mitochondrial DNA Depletion Syndrome, Hepatocerebral Form | Megacystis-microcolon-intestinal Hypoperistalsis Syndrome | Genee-Wiedemann Syndrome | Asplenia | Combined Deficiency Of Factor V And Factor VIII | Cancer, Colon | Small Lymphocytic Lymphoma | Kidney Stones | Budd-Chiari Syndrome | Hereditary Hemorrhagic Telangiectasia Type 2 | ACTH-independent Macronodular Adrenal Hyperplasia | Pneumoconiosis | Cutaneous T-cell Lymphoma | Dystonia Musculorum Deformans | Takotsubo Cardiomyopathy | Wagner Disease | Glutaric Aciduria Type 3 | Onchocerciasis | Bicuspid Aortic Valve | Spinocerebellar Ataxia Type 12 | Usher Syndrome Type II | Galactosemia | Camurati-Engelmann Disease | Compartment Syndrome | Giant Cell Arteritis | Actinomycetoma | Tibial Muscular Dystrophy | Alopecia Totalis | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | Cancer, Skin | Systemic Mastocytosis | Cyst | Chiari Malformation Type I | Macrophage Activation Syndrome | Hyperparathyroidism | Hyperglycemia | Pseudohypoparathyroidism Type 1C | Nemaline Myopathy 8 | Barrett Esophagus | Vascular Cognitive Impairment | Mitochondrial DNA Depletion Syndrome 13 | Bare Lymphocyte Syndrome | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Acute Leukemia | Non-small Cell Lung Cancer | Cryptosporidiosis | Hereditary Folate Malabsorption | Osteosarcoma | Light Chain Amyloidosis | Noonan Syndrome | Idiopathic Multicentric Castleman Disease | Hypoglycemia | Neurofibroma | Ebstein Anomaly | Kaposi Sarcoma | Sclerosing Cholangitis | Ependymoma | Diabetes Type 2 | Mitochondrial Encephalomyopathy | Sarcoidosis, Pulmonary | Primary Progressive Aphasia | Discoid Lupus Erythematosus | Chronic Kidney Disease | Pulmonary Tuberculosis | Myofibrillar Myopathy | Colitis, Lymphocytic | Enlarged Vestibular Aqueduct | Renpenning Syndrome | Marshall-Smith Syndrome | Alopecia Areata | Pyruvate Dehydrogenase Deficiency | Infectious Diarrhea | Hyperthermia, Malignant | Keratosis, Actinic | Multisystemic Smooth Muscle Dysfunction Syndrome | Spinocerebellar Ataxia Type 16 | Feingold Syndrome | Marfan Syndrome | Plasmacytoma | Encephalitis | Panniculitis | Creatine Deficiency Syndrome | Glycogen Storage Disease Type 9 | Fibromuscular Dysplasia | Blepharophimosis Syndrome | Anorectal Fistula | Congenital Poikiloderma | Pelizaeus-Merzbacher Disease | Familial Male-limited Precocious Puberty | Chronic Leukemia | Cystitis | Fanconi Anemia | Vitamin D Deficiency | Kashin-Beck Disease | Fowler's Syndrome | Schwartz-Jampel-Aberfeld Syndrome | Meckel-Gruber Syndrome | Primary Erythromelalgia | Ileitis | Spinocerebellar Ataxia Type 2 | Varices | Crouzon Syndrome With Acanthosis Nigricans | Hypertelorism | Tricho-hepato-enteric Syndrome | Crohn's Disease | Amelanotic Melanoma | Alpha-mannosidosis | Senior-Loken Syndrome | Malignant Fibrous Histiocytoma | Cardiomyopathy, Restrictive | T-cell Leukemia | Pelvic Inflammatory Disease | Hypotension, Orthostatic | Spondylocarpotarsal Synostosis Syndrome | GNE Myopathy | Marinesco-Sjogren Syndrome | Arteriovenous Malformations