Disease

Generalized Epilepsy With Febrile Seizures Plus

About the Disease
Generalized Epilepsy with Febrile Seizures Plus, also known as gefs+, is related to generalized epilepsy with febrile seizures plus, type 2 and generalized epilepsy with febrile seizures plus, type 1. An important gene associated with Generalized Epilepsy with Febrile Seizures Plus is SCN1B (Sodium Voltage-Gated Channel Beta Subunit 1), and among its related pathways/superpathways are Nervous system development and Transmission across Chemical Synapses. Affiliated tissues include brain, smooth muscle and endothelial, and related phenotypes are febrile seizure (within the age range of 3 months to 6 years) and generalized non-motor (absence) seizure

Common Targets
LGI1 | SCN3A | GABRG2 | SLC7A11 | PRRT2 | SCN9A | SCN1A | FGF13 | SCN2A | DEPDC5

疾病靶点研报
Generalized Epilepsy With Febrile Seizures Plus

Note: If you'd like to get a target analysis report for Generalized Epilepsy With Febrile Seizures Plus, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Generalized Epilepsy With Febrile Seizures Plus at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Myasthenia | Congenital Tufting Enteropathy | Erysipelas | Sickle Cell Anemia | Dysplastic Nevus | Bipolar Disorder | Anorchia | Mucolipidosis Type II | Fahr Disease | Hereditary Folate Malabsorption | Behcet's Disease | Congenital Lipoid Adrenal Hyperplasia | Muir-Torre Syndrome | Axenfeld-Rieger Syndrome | Weill-Marchesani Syndrome | Glycogen Storage Disease Type 1 | Venous Insufficiency | ADNP Syndrome | Anodontia | Acquired Partial Lipodystrophy | Amelanotic Melanoma | Tic Disorder | Pseudoexfoliation Syndrome | Leber Congenital Amaurosis | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Cerebellar Ataxia, Cayman Type | Senior-Loken Syndrome | Epidermolysis Bullosa | Adenomatoid Tumor | Anovulation | Neurofibromatosis | Retinal Telangiectasia | Esthesioneuroblastoma | Agnathia-Otocephaly Complex | Filariasis | CREST Syndrome | Japanese Encephalitis | Neural Tube Defect | Lung Diseases | POEMS Syndrome | Malnutrition | Double Outlet Right Ventricle | Autoimmune Interstitial Lung, Joint, And Kidney Disease | 3-M Syndrome | Congenital Disorders Of Glycosylation Type II | Fowler's Syndrome | Progressive External Ophthalmoplegia | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Ischemia | Cancer, Prostate | Alcoholism | Congenital Primary Aphakia | Urethritis | Long QT Syndrome Type 1 | Dysthymia | Whipple's Disease | Renal Oncocytoma | Hidradenitis | Chylomicron Retention Disease | Idiopathic Pulmonary Fibrosis | Thyroiditis, Autoimmune | Waardenburg Syndrome Type 4 | Shwachman-Bodian-Diamond Syndrome | Nance-Horan Syndrome | Chondromyxoid Fibroma | Blastoma, Pleuropulmonary | Allan-Herndon-Dudley Syndrome | Polyarteritis Nodosa | Kabuki Syndrome | Meniere's Disease | DOCK8 Immunodeficiency Syndrome | Porphyria, Acute Intermittent | Robinow Syndrome | Ollier Disease | Corneal Dystrophy | Osteonecrosis Of The Jaw | Systemic Lupus Erythematosus | Paroxysmal Kinesigenic Dyskinesia | Torticollis | Neurodegeneration Due To Cerebral Folate Transport Deficiency | Reye Syndrome | Intestinal Hypomagnesemia 1 | Alexander Disease | Charcot-Marie-Tooth Disease Type 4D | Preaxial Polydactyly | Vogt-Koyanagi-Harada Syndrome | Noonan Syndrome-like Disorder With Loose Anagen Hair | Keratitis-ichthyosis-deafness Syndrome | Mandibuloacral Dysplasia With Type A Lipodystrophy | Intracerebral Hemorrhage | Urea Cycle Disorder | Babesiosis | Familial Episodic Pain Syndrome | Albinism | Tinea Versicolor | Hyperuricemia | Chronic Beryllium Disease | 5-oxoprolinase Deficiency | Ocular Albinism Type 1 | Pure Red Cell Aplasia | Spinocerebellar Ataxia Type 16 | Encephalopathy | Keloid | Familial Hyperaldosteronism | Lipid Storage Myopathy | Spinocerebellar Ataxia Type 38 | Retinopathy Of Prematurity | Rhizomelic Chondrodysplasia Punctata | Omenn Syndrome | Scoliosis | Hyperinsulinemia | Multiple System Atrophy | Charcot-Marie-Tooth Disease Type 4 | Periventricular Leukomalacia | Gout | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Sulfite Oxidase Deficiency | Hereditary Inclusion Body Myopathy | Primary Carnitine Deficiency | Methylmalonic Acidemia | Coenzyme Q10 Deficiency | Communication Disorders | Neuromyotonia | Sturge-Weber Syndrome | Acrodysostosis | Esophagitis | Peripheral Neuropathy | Hepatorenal Syndrome | Diffuse Mesangial Sclerosis | Pneumonia, Bacterial | Richter's Syndrome | Cold-induced Sweating Syndrome | Familial Partial Lipodystrophy | Macrophagic Myofasciitis | Primary Familial Brain Calcification | Peeling Skin Syndrome, Acral Type | Moyamoya Disease | Megalencephaly | Sclerocornea | Niemann-Pick Disease, Type B | Paronychia | Lymphoma, B-cell | Pseudohermaphroditism | Krabbe Disease | Cataract | Congenital Absence Of Vas Deferens | Congenital Myopathy | Otitis Externa | Antley-Bixler Syndrome | Hyperprolactinemia | Restrictive Dermopathy | Narcolepsy | KBG Syndrome | Primary Progressive Nonfluent Aphasia | CHOPS Syndrome | Teratozoospermia | Spinocerebellar Ataxia Type 7 | Cardiospondylocarpofacial Syndrome | Tendinitis | Focal Cortical Dysplasia Type 2 | Lathosterolosis | Osteogenesis Imperfecta Type IV | Pyloric Stenosis, Infantile Hypertrophic | Cerebral Cavernous Malformations | Hepatitis, Alcoholic | Amebiasis | Vasculitis | Autosomal Recessive Congenital Ichthyosis | Meningitis | Niemann-Pick Disease | Renal Medullary Carcinoma | Anterior Segment Dysgenesis | Nail Disorder, Nonsyndromic Congenital | Frontometaphyseal Dysplasia | Hyper IgE Syndrome | GM2-gangliosidosis AB Variant | Idiopathic Multicentric Castleman Disease | Congenital Disorders Of Glycosylation | Hernia, Inguinal | Atelosteogenesis Type 1 | Histiocytic Sarcoma | Cardiomyopathy, Peripartum | Stroke | Neuromuscular Disorders | Progressive Osseous Heteroplasia | Alveolar Capillary Dysplasia | Lattice Corneal Dystrophy Type 1 | Diffuse Intrinsic Pontine Glioma | Hereditary Hemorrhagic Telangiectasia Type 2 | Hereditary Spherocytosis | Spondylocostal Dysostosis | Hereditary Sensory Neuropathy Type 1 | Thrombophlebitis | Peters-plus Syndrome | Cirrhosis | Small Lymphocytic Lymphoma | Anemia | Schizophrenia, Paranoid | Congenital Ichthyosiform Erythroderma | Hydrocephalus | Hypereosinophilic Syndrome | Dengue Shock Syndrome | Hemoglobinopathies | Leukoplakia, Oral | Retinopathy, Diabetic | Citrullinemia | Usher Syndrome | High Molecular Weight Kininogen Deficiency | Pernicious Anemia | Neurodermatitis | Short-chain Acyl-CoA Dehydrogenase Deficiency | Facioscapulohumeral Muscular Dystrophy Type 1 | X-linked Acrogigantism | Glycogen Storage Disease | Perivascular Epithelioid Cell Tumor | Spinocerebellar Ataxia Type 10 | T-cell Prolymphocytic Leukemia | Tardive Dyskinesia | Scleroderma | Mountain Sickness | Lipid Metabolism Disorders | Meningococcal Infections | Charcot-Marie-Tooth Disease Type 2T | Erdheim-Chester Disease | Cerebrovascular Disorders | Hypersensitivity Pneumonitis | Binge Eating Disorder | Acute Kidney Injury | Congenital Poikiloderma | Microcephaly | Coronary Restenosis | Familial Cerebral Amyloid Angiopathy | Gilbert Syndrome | Infantile Spasm | Leukemia-lymphoma, Adult T-cell | Hypohidrotic Ectodermal Dysplasia, X-linked | Pituitary Dwarfism | Histoplasmosis | Lipodystrophy | Diabetic Encephalopathy | Hypomyelination With Atrophy Of Basal Ganglia And Cerebellum | Neurofibroma, Plexiform | Gastrointestinal Disorders | Pyoderma Gangrenosum | Hereditary Elliptocytosis | Epidermolysis Bullosa Simplex, Localized | DEND Syndrome | Episodic Ataxia Type 2 | Vitamin K Deficiency | Adenomyosis | Spinal Muscular Atrophy Type 3 | Seasonal Mood Disorder | CHARGE Syndrome | Bicuspid Aortic Valve | Arthritis | Craniofrontonasal Syndrome | Sweet Syndrome | Mucolipidosis | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Noonan Syndrome | Amenorrhea | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Osteogenesis Imperfecta | Spinocerebellar Ataxia Type 31 | Ovarian Hyperstimulation Syndrome | Schnitzler Syndrome | Tatton-Brown-Rahman Syndrome | Coronary Artery Disease | Large Granular Lymphocytic Leukemia | Autoimmune Autonomic Ganglionopathy | Infantile Nephropathic Cystinosis | Tangier Disease | Lesch-Nyhan Syndrome | Arterial Tortuosity Syndrome | Tibial Muscular Dystrophy | Motor Neuron Diseases | Juvenile Myelomonocytic Leukemia | Paternal Uniparental Disomy Of Chromosome 14 | Usher Syndrome Type I | Asperger Syndrome | Bartter Syndrome | Macular Corneal Dystrophy Type 1 | Primary Progressive Aphasia | Genee-Wiedemann Syndrome | Episodic Ataxia | Carcinoma, Small Cell | Pituitary Disorders | Proteasome-associated Autoinflammatory Syndrome 2 | Sezary Syndrome | Lissencephaly 2 | Wiskott-Aldrich Syndrome | Infertility, Male | Craniopharyngioma | Peritonitis | Netherton Syndrome | Papilledema | Low Phospholipid Associated Cholelithiasis | Seizures | Macular Corneal Dystrophy | Eczema | Facioscapulohumeral Muscular Dystrophy Type 2 | Infantile Refsum Disease | Multiple Sclerosis, Chronic Progressive | Klinefelter Syndrome | Marfan Syndrome | Congenital Afibrinogenemia | Mumps | Onchocerciasis | Hypertelorism | Chorea | Hypercalciuria | Retinitis | Androgenic Alopecia | Lennox-Gastaut Syndrome | Ophthalmoplegia | Hydrolethalus Syndrome | Tyrosinemia Type 1 | Anorexia Nervosa | Phosphoglycerate Dehydrogenase Deficiency | Polycystic Kidney, Autosomal Dominant | Hamartoma | Premature Ejaculation | Macrophage Activation Syndrome | Postpartum Depression | Coffin-Lowry Syndrome | Necrotizing Autoimmune Myopathy | Kindler Syndrome | Giant Cell Glioblastoma | Dystrophy, Cone-rod | Myosin Storage Myopathy | Stiff-man Syndrome | Christianson Syndrome | Echinococcosis | Seminoma | Choriocarcinoma | Panniculitis | Parapsoriasis | Aicardi-Goutieres Syndrome | Hypertension, Portal | Hyperparathyroidism | Cholangiocarcinoma | Holt-Oram Syndrome | Epilepsy, Generalized | Medulloblastoma | Hartnup Disease | Periventricular Nodular Heterotopia | Crigler-Najjar Syndrome | FG Syndrome | Plasmacytoma | Trichorhinophalangeal Syndrome | Spinocerebellar Ataxia Type 42 | Glomerulonephritis, Membranoproliferative | Glycogen Storage Disease Type 1b | Waldenstrom Macroglobulinemia | Retinal Degeneration | AIDS Dementia Complex | Follicular Dendritic Cell Sarcoma | Spinocerebellar Ataxia Type 3 | Conn Syndrome | Pyelonephritis | Osmotic Demyelination Syndrome | Tuberculous Meningitis | Asthma, Nocturnal | Rheumatoid Arthritis | Xeroderma Pigmentosum | Pineoblastoma | Alzheimer Disease, Late Onset | Schizophrenia | Cholestasis | Spinocerebellar Ataxia Type 23 | Glaucomatocyclitic Crisis | Tularemia | Succinic Semialdehyde Dehydrogenase Deficiency | Dyslipidemia | Peyronie's Disease | Cardiofaciocutaneous Syndrome | Hennekam Lymphangiectasia-lymphedema Syndrome | Hypertensive Retinopathy | Cancer, Breast | Fukuyama Congenital Muscular Dystrophy | Plasma Cell Dyscrasia | Takayasu's Arteritis | Pemphigus | Gerodermia Osteodysplastica | Cheilitis | Pulmonary Vein Stenosis | Tietze Syndrome | Retinitis Pigmentosa 3 | HUPRA Syndrome | Precocious Puberty | Polycystic Liver | Generalized Epilepsy With Febrile Seizures Plus | Spinocerebellar Ataxia Type 28 | Mucormycosis | Dementia | Pemphigus Vulgaris | Polycystic Kidney, Autosomal Recessive | Early Infantile Epileptic Encephalopathy | Walker-Warburg Syndrome | Chromosome 9q34.3 Deletion Syndrome