Disease

Pineoblastoma

About the Disease
Pineoblastoma, also known as tumor of the pineal region, is related to retinoblastoma and hydrocephalus. An important gene associated with Pineoblastoma is DICER1 (Dicer 1, Ribonuclease III), and among its related pathways/superpathways are Neuroscience and Direct p53 effectors. The drugs Lenograstim and Adjuvants, Immunologic have been mentioned in the context of this disorder. Affiliated tissues include brain, pineal and thyroid, and related phenotypes are pinealoma and headache

Common Targets
TOP2B | G5728 | SERPINB5 | TFRC | HBS1L | BDP1 | FBN1 | SREBF2 | MAP2K7 | CYSLTR1 | NFKB2 | MGLL | BRF1 | CPLANE1 | LY75-CD302 | KDM5C | ARRB2 | GATA1 | JARID2 | ABCD2 | TCF4 | ZNF789 | TSHZ3 | XRCC6 | KCNN4 | FGFR1 | TGFBR1 | KAT6A | HLA-DRA | DNAH6 | OR1D5 | KRTAP4-4 | G4233 | AKT2 | DICER1 | TET1 | RBBP6 | SP110 | HINT1 | KCNA5 | POU1F1 | CREG1 | PTK2B | PRKCD | NELFE | RDH16 | CAPN1 | GHR | GPAT2 | ARID3A | TRH | CHD8 | ELN | ERBIN | TTN | CREBBP | DDX17 | PPP1CC | CYP4F2 | ACOT6 | SLC38A10 | AGO3 | ZDHHC11 | LIG1 | ALPK2 | KMT5A | VTN | COL2A1 | MYO3A | SALL3 | CD276 | RASSF1 | BARD1 | OR52H1 | ASTL | ZNF8 | CSMD2 | TCF7L2 | ZNF583 | FOS | GPX5 | RAD51B | BTBD6 | PSMC4 | ECD | ZNF292 | ENPP2 | TXLNA | HECTD4 | FCER1G | RASA3

疾病靶点研报
Pineoblastoma

Note: If you'd like to get a target analysis report for Pineoblastoma, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Pineoblastoma at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Diffuse Mesangial Sclerosis | Congenital Hemolytic Anemia | Glutaric Aciduria Type 2 | Arthrogryposis | Salla Disease | Cartilage Disorders | Glomerulonephritis | Meconium Ileus | Pseudoexfoliation Syndrome | Long QT Syndrome Type 2 | Bardet-Biedl Syndrome | LRBA Deficiency | Galloway-Mowat Syndrome | Hypertension, Renal | Choroiditis | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Alpha-mannosidosis | Cherubism | Thanatophoric Dysplasia | Crigler-Najjar Syndrome | Craniometaphyseal Dysplasia | Usher Syndrome Type IIC | Ichthyosis Bullosa Of Siemens | Schizotypal Personality Disorder | Endometrial Hyperplasia | Bloom Syndrome | Bone Giant Cell Tumor | Spinal And Bulbar Muscular Atrophy | Spinal Muscular Atrophy Type 2 | Spondylo-ocular Syndrome | Pemphigus Vulgaris | Axenfeld-Rieger Syndrome | Hypokalemic Periodic Paralysis | Thyrotoxic Periodic Paralysis | Malaria | Lymphoma, AIDS-related | Schizoaffective Disorder | Schwannomatosis | Growth Hormone Excess | Centronuclear Myopathy | Peyronie's Disease | Ghosal Syndrome | Osteogenesis Imperfecta Type V | Sjogren Syndrome | Dyggve-Melchior-Clausen Disease | Niemann-Pick Disease, Type C | Proximal Symphalangism | Ocular Hypertension | Dent Disease | Esthesioneuroblastoma | Renal Medullary Carcinoma | Placenta Previa | Myositis, Focal | Schuurs-Hoeijmakers Syndrome | Gastritis, Atrophic | Alkaptonuria | Joubert Syndrome | Split Hand-foot Malformation | Adenocarcinoma | Tetraplegia | Addison Disease | Aldosterone Synthase Deficiency | Congenital Heart Block | Retinitis | Bronchiolitis | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Dementia | Leiomyoma | Trigonocephaly | Acromegaly | Diffuse Palmoplantar Keratoderma | Varices | Early Infantile Epileptic Encephalopathy 4 | 3-methylcrotonyl-CoA Carboxylase Deficiency | Chronic Kidney Disease | Hypoplastic Left Heart Syndrome | ADNP Syndrome | Cri-du-chat Syndrome | Acute Motor Axonal Neuropathy | Familial Male-limited Precocious Puberty | Portal Vein Thrombosis | Alstrom Syndrome | Transthyretin-related Amyloidosis | Blastoma, Pleuropulmonary | Beare-Stevenson Syndrome | Phosphoenolpyruvate Carboxykinase Deficiency, Cytosolic | Hyperuricemic Nephropathy, Familial Juvenile | Neurotoxicity | Neurocutaneous Melanocytosis | Smith-Lemli-Opitz Syndrome | Tangier Disease | Hermansky-Pudlak Syndrome | Keratopathy | Presbyopia | Atherosclerosis | Hydrocephalus | Congenital Torticollis | Noonan Syndrome | Metanephric Adenoma | Thromboembolism | Transcobalamin Deficiency | Granuloma Annulare | Fibrosis | Retinal Diseases | Reflex Epilepsy | Marfan Syndrome | Nephrotic Syndrome | Charcot-Marie-Tooth Disease Type 4 | Steel Syndrome | Open-angle Glaucoma | Menetrier Disease | Megalencephaly | Coenzyme Q10 Deficiency | Donnai-Barrow Syndrome | Optic Neuropathy | Spinocerebellar Ataxia Type 7 | Zollinger-Ellison Syndrome | Hyperthermia, Malignant | LMNA-related Congenital Muscular Dystrophy | Dermatitis | Lipid Storage Myopathy | Disseminated Intravascular Coagulation | Urethritis | Hyperlipidemia | Heroin Dependence | Micro Syndrome | Wolfram Syndrome | Borjeson-Forssman-Lehmann Syndrome | Stevens-Johnson Syndrome | Headache | Amenorrhea | Facioscapulohumeral Muscular Dystrophy | Central Core Disease | Lymphoma, Follicular | Primary Lateral Sclerosis | Hidradenitis Suppurativa | Erythrokeratodermia Variabilis | Sickle Cell Anemia | FG Syndrome | Benign Familial Infantile Seizures | Focal Segmental Glomerulosclerosis | Hyperbilirubinemia, Neonatal | Proopiomelanocortin Deficiency | Primary Progressive Nonfluent Aphasia | Ameloblastoma | Homocystinuria | GM2-gangliosidosis AB Variant | Wolman Disease | Tyrosinemia Type 2 | Hereditary Elliptocytosis | Persistent Fetal Circulation | Acrodermatitis Enteropathica | Absence Epilepsy | Polycystic Ovary Syndrome | Agoraphobia | Rhabdomyosarcoma, Alveolar | Communication Disorders | Tricho-hepato-enteric Syndrome | Cholesteryl Ester Storage Disease | Greig Cephalopolysyndactyly Syndrome | Aplastic Anemia | Hypopigmentation | X-linked Creatine Transporter Deficiency | Craniofacial Dysostosis | Kabuki Syndrome | Erectile Dysfunction | Cervical Dystonia | Rash | Pineoblastoma | ICF Syndrome | Ischemia | Chondrodysplasia Punctata | Cyclic Vomiting Syndrome | Tay-Sachs Disease | Adenoid Cystic Carcinoma | Spinocerebellar Ataxia Type 21 | Gangliosidosis, GM1 | Congenital Dyserythropoietic Anemia Type 1 | Mandibuloacral Dysplasia With Type A Lipodystrophy | Hereditary Sensory And Autonomic Neuropathy | Hypocalcemia | Basan Syndrome | Spinocerebellar Ataxia Type 23 | Muir-Torre Syndrome | Melanoma | Pregnancy, Ectopic | Lateral Meningocele Syndrome | Schamberg Disease | Osteosarcoma | Fowler's Syndrome | Lymphoma Lymphoblastic | Mevalonate Kinase Deficiency | Kaposi Sarcoma | Lassa Fever | Hypopituitarism | Hepatitis D | Arteriosclerosis | Riboflavin Transporter Deficiency Neuronopathy | Thrombotic Microangiopathy | Peutz-Jeghers Syndrome | Primary Erythromelalgia | Encephalitis, Tick-borne | Pyruvate Carboxylase Deficiency Disease | Malignant Fibrous Histiocytoma | Alveolar Capillary Dysplasia | Chronic Periodontitis | Peroxisomal Disorder | Hypercholesterolemia | Seasonal Mood Disorder | Contact Dermatitis | Adams-Oliver Syndrome | Herpes Genitalis | Corneal Dystrophy | Cirrhosis | Sponastrime Dysplasia | Pemphigus Foliaceus | Pierson Syndrome | Facioscapulohumeral Muscular Dystrophy Type 1 | Uveitis, Anterior | Astigmatism | Cellulitis | Carotid Artery Disease | Tinea Versicolor | Mucolipidosis Type III | Double Outlet Right Ventricle | Familial Episodic Pain Syndrome | Lipodystrophy | Myelitis | Ehlers-Danlos Syndrome With Progressive Kyphoscoliosis, Myopathy, And Hearing Loss | Spondylocarpotarsal Synostosis Syndrome | Giant Axonal Neuropathy | Angioedema, Hereditary | Spondylometaphyseal Dysplasia | KBG Syndrome | Autosomal Recessive Spastic Paraplegia Type 35 | Early Infantile Epileptic Encephalopathy 28 | Hemochromatosis Type 2 | Sensory Ataxic Neuropathy, Dysarthria, And Ophthalmoparesis | Greenberg Dysplasia | Keratosis, Seborrheic | Spinocerebellar Ataxia Type 40 | Peripheral T-cell Lymphoma | Diabetes Type 1 | Narcolepsy | Postaxial Polydactyly | Platelet Disorders | Distal Myopathy 2 | Muckle-Wells Syndrome | Glycogen Storage Disease Type 5 | Ataxia-ocular Apraxia 2 | Seminoma | Congenital Stromal Corneal Dystrophy | Neuroma | Okihiro Syndrome | Clouston Hidrotic Ectodermal Dysplasia | Aarskog-Scott Syndrome | Bacterial Meningitis | Fanconi Syndrome | Trichorhinophalangeal Syndrome | Dominant Optic Atrophy | Progressive External Ophthalmoplegia | COACH Syndrome | Fahr Disease | Tietze Syndrome | Premature Ejaculation | Myoclonic Epilepsy With Ragged Red Fibers | Gastrointestinal Disorders | B-cell Chronic Lymphocytic Leukemia | Cryptorchidism | Cranial Nerve Disease | Keloid | Hypertriglyceridemia | Palsy, Cerebral | Metatropic Dysplasia | CHARGE Syndrome | Pompe Disease | Auriculocondylar Syndrome | Kidney Stones | Osteoporosis-pseudoglioma Syndrome | Intracranial Hypertension | Lathosterolosis | Endocarditis | Antisocial Personality Disorder | Porencephaly | Alzheimer Disease, Late Onset | Conjunctivitis | Plasmacytoma | Hernia, Inguinal | McKusick Type Metaphyseal Chondrodysplasia | Chronic Mucocutaneous Candidiasis | Evans Syndrome | Dowling-Degos Disease | Non-bullous Congenital Ichthyosiform Erythroderma | Sporadic Hemiplegic Migraine | Chromosome 5q Deletion Syndrome | Papillon-Lefevre Syndrome | Intestinal Pseudo-obstruction | Mucolipidosis Type IV | Ichthyosis, X-linked | Myofibromatosis | Pulmonary Veno-occlusive Disease | Wolff-Parkinson-White Syndrome | Treacher Collins Syndrome | Thrombocytopenia | Metabolic Syndrome | Ameloblastic Carcinoma | Cardiomyopathy, Dilated, 1L | T-cell Prolymphocytic Leukemia | Lamellar Ichthyosis | Stroke, Ischemic | Myositis | AIDS | Anthrax | Chronic Myeloid Leukemia | Retinopathy, Diabetic | Astrocytoma, Anaplastic | Thymoma, Malignant | Restless Legs Syndrome | Phosphoglycerate Dehydrogenase Deficiency | Torticollis | Glaucoma, Congenital | Intestinal Tuberculosis | Lattice Corneal Dystrophy Type 1 | Krabbe Disease | Hemorrhage | Sarcoma | Idiopathic Multicentric Castleman Disease | Mood Disorder | Von Hippel-Lindau Disease | Blue Nevus | Enlarged Vestibular Aqueduct | Loeys-Dietz Syndrome | Exostoses | Cancer, Colon | Thrombophlebitis | Hepatoblastoma | Lupus Erythematosus | Pyruvate Kinase Deficiency | Scleroderma | Hypothalamic Obesity | Carbamoyl Phosphate Synthetase I Deficiency | Infantile Nephropathic Cystinosis | Amblyopia | Synovitis | Withdrawal Syndrome | Polyradiculopathy | Hairy Cell Leukemia | Congenital Absence Of Vas Deferens | Syphilis | Inflammatory Joint Disease | Mountain Sickness | Motion Sickness | Empyema | Spinocerebellar Ataxia Type 27 | X-linked Acrogigantism | Adenylosuccinate Lyase Deficiency | Prolymphocytic Leukemia | GNE Myopathy | Atopic Dermatitis | Chromosome 16p11.2 Deletion Syndrome | Lymphedema-distichiasis Syndrome | Acromicric Dysplasia | Congenital Hereditary Endothelial Dystrophy Type I | Hyperferritinemia-cataract Syndrome | Juvenile Hyaline Fibromatosis | Acute Lymphocytic Leukemia | Familial Isolated Hyperparathyroidism | Epidermolysis Bullosa Simplex, Localized | Alagille Syndrome | Waardenburg Syndrome Type 4A | Autoimmune Polyendocrine Syndrome | Rhabdomyosarcoma | Senior-Loken Syndrome | Infectious Diarrhea | X-linked Myotubular Myopathy | Oculocutaneous Albinism | Hyperglycemia | Holoprosencephaly | 3-hydroxy-3-methylglutaryl-CoA Synthase Deficiency | Lymphoproliferative Disorders | Disseminated Superficial Actinic Porokeratosis | POEMS Syndrome | Sitosterolemia | Fibronectin Glomerulopathy | Learning Disability | Thanatophoric Dysplasia Type 1 | Peeling Skin Syndrome Type B | Lymphoma | Trichothiodystrophy | Vitamin A Deficiency | Meningioma | Generalized Epilepsy With Febrile Seizures Plus | Leber Hereditary Optic Neuropathy | Scleroderma, Diffuse | Polydactyly | Peritonitis | Cholangitis | Ligneous Conjunctivitis | Tendinopathy | Tardive Dyskinesia