Disease

Hypertriglyceridemia

About the Disease
Hypertriglyceridemia, Transient Infantile, is also known as transient infantile hypertriglyceridemia and hepatosteatosis, and has symptoms including hypertriglyceridemic waist An important gene associated with Hypertriglyceridemia, Transient Infantile is GPD1 (Glycerol-3-Phosphate Dehydrogenase 1). The drugs Ciprofibrate and Glucagon have been mentioned in the context of this disorder. Affiliated tissues include liver, skeletal muscle and heart, and related phenotypes are splenomegaly and hepatomegaly

Common Targets
AKR1C4 | APOE | GLP1R | G5743 | NREP | GCGR | CHN2 | BUD13 | FDXR | Acetyl-CoA Carboxylases (ACC) (nonspecified subtype) | LMF1 | MTHFR | Fibroblast Growth Factor Receptor (FGFR) (nonspecified subtype) | NADPH Oxidase (nonspecified subtype) | C3orf33 | MMP1 | PASK | ERCC6L2 | ZNF322 | ITGA1 | NCAN | CETP | KNL1 | LPL | GPR119 | INSIG1 | FFAR4 | MOGAT2 | G5243 | ZPR1 | ANGPTL4 | TIMD4 | TRIB1 | APOA4 | ADI1 | LDLR | MLPH | MAGEC1 | TSPOAP1 | DGAT1 | gamma-Secretase | PDXDC1 | HFE | APOA5 | MGAT2 | TRPM6 | BMP7 | BUB1B | PRR21 | NCOA4 | CYSLTR1 | NAT2 | TEX26 | C12orf43 | PHF21A | RBFOX2 | ANGPTL3 | AGT | DGAT2 | ADIPOQ | G7124 | MLXIPL | AMP-activated protein kinase (AMPK) | SLC15A1 | CILP2 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | HIF1A | STX2 | RPS6KB1 | MMP3 | GALNT2 | PINX1 | ELANE | WWOX | LOC105369410 | MZF1 | NR0B2 | SBF2 | PPARA | CAPN3 | CNR2 | HHIPL1 | ADAM17 | LAMC1 | ULK4 | OR4K5 | APOC3 | KAT6A | XKR6 | Oxysterols receptor LXR (nonspecified subtype) | ANGPTL8 | G3569 | BCO1 | Peroxisome Proliferator-Activated Receptors (PPAR) (nonspecified subtype) | FAAP24 | PCSK9 | HMGCR | NPPA | NPPA-AS1 | C2orf16 | GIPR | ABCA1 | ZNF280A | AGXT2 | NF-kappaB (NFkB) | GCKR | Casein kinase II (CKII) | LAMC2 | INSR | PKD1L1 | LINC02209 | Estrogen receptor (nonspecified subtype) | SYCE1L | RAB20 | CES1 | HSD11B1 | XPO4 | PPARD | FRMD5 | GPD1 | GPIHBP1 | RNF186 | DPP4 | K(ATP) Channel (nonspecified subtype) | MTTP | EIF2AK1 | GALK2 | PRUNE2 | PNPLA2 | G3605 | P2X Receptor (nonspecified subtype) | LRP1 | Prostanoid TP receptor (nonspecified subtype) | KRTAP4-5 | LIPC | LNX2 | STAB1 | PTGS1 | SLC25A40 | NR1H4 | PPARG | ERO1B | RXRA | HNF1A | TBL2 | F2RL3 | G3630 | TRIB3 | WNT10A | CDC42BPA | CYSLTR2 | WDR18 | BAZ1B | PIM1 | AKR1B10 | APOA1 | TTN | CREB3L3 | Sterol Regulatory Element-Binding Protein (nonspecified subtype) | ADRB2 | SMCHD1 | OR4C16 | EXOC3L4 | ANKMY2 | ERP44 | BMPR1A | APOC2 | NOX3 | KRTAP4-11 | FASTKD1 | PON2 | APOB | TRDMT1 | FTO | FABP2 | cGMP-inhibited 3',5'-cyclic phosphodiesterase 3 (PDE3) (nonspecified subtype) | ACACA | VTI1A | IRS1 | G4233 | TP53BP1 | NADPH Oxidase Complex | KRT32 | SIK3 | RASSF7 | G5562 | CFAP58 | ALOX5

疾病靶点研报
Hypertriglyceridemia

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