Disease

Anorexia Nervosa

About the Disease
Anorexia Nervosa, also known as anorexia nervosa, susceptibility to, is related to eating disorder and body dysmorphic disorder, and has symptoms including decrease in appetite An important gene associated with Anorexia Nervosa is HTR2A (5-Hydroxytryptamine Receptor 2A), and among its related pathways/superpathways are GPCR downstream signalling and Signal Transduction. The drugs Aripiprazole and Fluoxetine have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and prefrontal cortex, and related phenotypes are Reduced mammosphere formation and nervous system

Common Targets
HTR3A | 5-Hydroxytryptamine Receptor 3 (5-HT3 receptor) (nonspecified subtype) | SULT1A1 | FFAR4 | SLC22A1 | Corticotropin-Releasing Factor (CRF) Receptor (nonspecified subtype) | GHSR | GHRL | CNR2 | Metabotropic glutamate (mGluR) receptor (nonspecified subtype) | ACE | VGLL4 | COL4A5 | DRD4 | NAT2 | Gamma-Aminobutyric acid type B receptor | DRD2 | EPHX2 | ESR2 | Alpha-2 Adrenergic receptors (nonspecified subtype) | GFRAL | COMT | Estrogen receptor (nonspecified subtype) | TRPM8 | GH1 | HTR1A | PGR | DIP2A | CNR1 | SLC6A2 | UGT1A7 | G23411 | ANKK1 | TNFSF11 | HCRTR1 | LEAP2 | HTR2B | HSD11B1 | PPP3CA | TRPV1 | SAMD5 | TRPV2 | LEP | G2099 | NTRK3 | G9429 | CLRN1-AS1 | ADRA2A | NR3C1 | Nicotinic alpha4beta2 receptor | PDK4 | CES1 | SLC19A1 | OPRL1 | MC3R | UGT1A6 | HTR3C | G367 | NPY5R | NPY4R | NNAT | ADRB1 | HCRTR2 | DRD1 | CHRM3 | HDAC4 | LEPR | NOS3 | SLC6A4 | GHR | LINC02210-CRHR1 | HTR3B | CRHR1 | CNTNAP2 | HTR2A | TRPA1 | HTR1B | BLTP3A | AGTR1 | CES1P1 | SYNE1 | UGT1A1 | MC4R | CRB1 | MYO1D | AKT3 | EPHX1 | WDR11 | ANTXR2 | NQO1 | CSGALNACT1 | HTR2C | PRKAR2B | SLC6A3 | GPR55 | OPCML | OXTR | CHRNB2 | PRKG1 | ZNF833P | Melanin-concentrating hormone (MCH) receptor (nonspecified subtype) | DPYD | SLC47A1 | MC5R | MIR4761 | SOX2-OT | MC1R | NPY4R2 | BDNF

疾病靶点研报
Anorexia Nervosa

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