Currarino Syndrome

About the Disease
Currarino Syndrome, also known as currarino triad, is related to anus, imperforate and sacral defect with anterior meningocele, and has symptoms including chronic constipation An important gene associated with Currarino Syndrome is MNX1 (Motor Neuron And Pancreas Homeobox 1), and among its related pathways/superpathways is Dopaminergic neurogenesis. Affiliated tissues include bone, uterus and kidney, and related phenotypes are aplasia/hypoplasia of the sacrum and sacrococcygeal teratoma

Common Targets
ARID5A | MNX1 | CTNNB1 | NCAPD3 | ETV3L

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