Disease

Keratosis

About the Disease
Keratosis, also known as actinic keratosis, is related to keratosis pilaris atrophicans and keratosis, seborrheic, and has symptoms including exanthema, pruritus and trichorrhexis invaginata. An important gene associated with Keratosis is CTSC (Cathepsin C), and among its related pathways/superpathways are Nervous system development and Keratinization. The drugs Lidocaine and Hydrogen peroxide have been mentioned in the context of this disorder. Affiliated tissues include skin, kidney and liver, and related phenotypes are homeostasis/metabolism and growth/size/body region

Common Targets
RARA | FLG | TYR | DSG4 | ATP2A2 | SERPINB7 | RARG | G8878

疾病靶点研报
Keratosis

Note: If you'd like to get a target analysis report for Keratosis, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Keratosis at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Primrose Syndrome | Papulopustular Rosacea | Sandhoff Disease | Anorchia | Carbamoyl Phosphate Synthetase I Deficiency | Osteoporosis, Postmenopausal | Mucolipidosis Type IV | Arts Syndrome | Chronic Thromboembolic Pulmonary Hypertension | Aspergillosis | Reticular Dysgenesis | Adenosine Deaminase 2 Deficiency | Hereditary Hemorrhagic Telangiectasia | Gastroenteritis | Nicotine Dependence | WAGR Syndrome | Pulmonary Veno-occlusive Disease | Sarcoidosis | Charcot-Marie-Tooth Disease Type 2T | Bloom Syndrome | Fundus Albipunctatus | Tietze Syndrome | Cancer, Breast | Pulmonary Alveolar Microlithiasis | Choreoathetosis, Hypothyroidism, And Neonatal Respiratory Distress | Renal Hypouricemia | Gestational Trophoblastic Disease | Cenani-Lenz Syndactyly Syndrome | Hemimegalencephaly | Intestinal Hypomagnesemia 1 | Carcinoma, Squamous Cell | Johanson-Blizzard Syndrome | T-cell Lymphoma, Subcutaneous Panniculitis-like | Cantu Syndrome | Epidermolysis Bullosa | Anorexia Nervosa | Adrenal Insufficiency | Thyroid Dyshormonogenesis | Periodontitis | Acral Lentiginous Melanoma | Epilepsy | Anxiety Disorders | Coloboma | Endometrial Hyperplasia | Pancreatitis, Chronic | Schwannomatosis | Primary Lateral Sclerosis | Alzheimer Disease, Late Onset | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Acromesomelic Dysplasia | Allergic Contact Dermatitis | Raynaud Phenomenon | Neutrophilia | Myoclonus-dystonia Syndrome | Muckle-Wells Syndrome | Corneal Edema | Camptocormia | Diabetes Type 1 | Gingivitis | Hereditary Neuropathy With Liability To Pressure Palsies | Campomelic Dysplasia | Diabetes | Acute Myeloid Leukemia | B-cell Prolymphocytic Leukemia | Postaxial Polydactyly | Becker Muscular Dystrophy | Hypertension, Portal | Pulmonary Alveolar Proteinosis | Aneurysm, Thoracic Aortic | Cri-du-chat Syndrome | Fibrodysplasia Ossificans Progressiva | Hypertension, Pulmonary | Protein S Deficiency | Chronic Kidney Disease | Carney Triad | IgA Nephropathy | Congenital Dyserythropoietic Anemia Type 4 | Glycogen Storage Disease Type 4 | Benign Recurrent Intrahepatic Cholestasis 1 | Wolfram Syndrome 2 | Acrodermatitis | Microtia | Hyperhomocysteinemia | Hemophilia | Lissencephaly 2 | Early Infantile Epileptic Encephalopathy | Bipolar Disorder | Chordoid Glioma | Angiodysplasia | Tetraplegia | Calcium Pyrophosphate Deposition Disease | Schnitzler Syndrome | Hartnup Disease | Alkaptonuria | Episodic Ataxia Type 2 | Retinal Coloboma | Dubin-Johnson Syndrome | Blomstrand Osteochondrodysplasia | Epiphyseal Chondrodysplasia, Miura Type | Gigantism | Guanidinoacetate Methyltransferase Deficiency | Bronchitis, Chronic | Hemolytic Uremic Syndrome | Pierpont Syndrome | Cataplexy | NGLY1 Deficiency | Hereditary Pyropoikilocytosis | Antithrombin III Deficiency | Heterotopic Ossification | Wieacker-Wolff Syndrome | Eiken Syndrome | Metabolic Diseases | Waldenstrom Macroglobulinemia | Sick Sinus Syndrome | Autonomic Neuropathy | Enterocolitis, Necrotizing | Atherosclerosis | Ligneous Conjunctivitis | Cysticercosis | Diastrophic Dysplasia | Lymphedema | Opisthorchiasis | Bursitis | Poikiloderma With Neutropenia | Pituitary Dwarfism | Best Macular Dystrophy | Supravalvular Aortic Stenosis | Spinocerebellar Ataxia Type 23 | Papilledema | Short-chain Acyl-CoA Dehydrogenase Deficiency | Odonto-onycho-dermal Dysplasia | Purpura | Hereditary Folate Malabsorption | Colon Adenoma | Progressive Familial Intrahepatic Cholestasis Type 2 | Personality Disorders | Impetigo | Thrombosis | Proximal Symphalangism | Moyamoya Disease | Schistosomiasis | SAPHO Syndrome | Migraine | Hypophosphatemic Rickets, Autosomal Recessive, 1 | Hyperinsulinemic Hypoglycemia | Aldosterone Synthase Deficiency | Anorectal Fistula | Williams Syndrome | Malaria, Cerebral | Craniopharyngioma | Cirrhosis | Transient Bullous Dermolysis Of The Newborn | Pyruvate Kinase Deficiency | Takotsubo Cardiomyopathy | Paternal Uniparental Disomy Of Chromosome 14 | Nager Acrofacial Dysostosis | Trichotillomania | Pontocerebellar Hypoplasia Type 2 | Congenital Mirror Movements | Giant Axonal Neuropathy | Myofibromatosis | Mitochondrial DNA Depletion Syndrome | TARP Syndrome | Familial Cerebral Amyloid Angiopathy | Hemangioma | Abetalipoproteinemia | Stroke, Ischemic | Spinocerebellar Ataxia Type 10 | Adenoid Cystic Carcinoma | Sarcosinemia | Von Willebrand Disease | Patent Foramen Ovale | Multiple Sclerosis, Relapsing-remitting | Bronchitis | Anterior Segment Dysgenesis | Hypertension | Polycystic Liver | Giant Cell Arteritis | Hyperparathyroidism | VACTERL/VATER Association | Spinal Muscular Atrophy Type 3 | Primary Hyperoxaluria Type 1 | Hartsfield Syndrome | Potocki-Shaffer Syndrome | Nanophthalmos | Chondrodysplasia Punctata 2, X-linked Dominant | Joubert Syndrome | Ileitis | Shwachman-Bodian-Diamond Syndrome | Bartter Syndrome | Pancreatitis | Rhizomelic Chondrodysplasia Punctata | Vestibular Disease | Muscle Wasting | Dengue Hemorrhagic Fever | Graft-versus-host Disease | Stevens-Johnson Syndrome | Poretti-Boltshauser Syndrome | Blue Rubber Bleb Nevus Syndrome | Chanarin-Dorfman Syndrome | Poirier-Bienvenu Neurodevelopmental Syndrome | Uremia | C3 Glomerulopathy | Cystinuria | Congenital Dyserythropoietic Anemia | Hyperlipidemia, Familial Combined | Scapuloperoneal Myopathy, X-linked Dominant | Premature Ejaculation | Silicosis | Myopathy | Charcot-Marie-Tooth Disease Axonal Type 2N | Pre-eclampsia | Disseminated Superficial Actinic Porokeratosis | Familial Partial Lipodystrophy | Trichomegaly | Spondylolisthesis | Angioedema, Acquired | Multiple Sclerosis, Chronic Progressive | Multiple Sclerosis, Primary Progressive | Intermittent Explosive Disorder | Polyradiculopathy | Hyperparathyroidism, Primary | Ureteropelvic Junction Obstruction | Aplasia Cutis Congenita | Kearns-Sayre Syndrome | Glioblastoma | Tylosis With Esophageal Cancer | Lattice Corneal Dystrophy | Genitopatellar Syndrome | Niemann-Pick Disease | T-cell Leukemia | Imerslund-Grasbeck Syndrome | Hyperparathyroidism-jaw Tumor Syndrome | Cerebrotendinous Xanthomatosis | Mood Disorder | Gliosarcoma | Citrullinemia | Retinitis | 3-hydroxy-3-methylglutaric Aciduria | Myocarditis | Primary Ovarian Insufficiency | Palmoplantar Keratoderma | Polymicrogyria | GAPO Syndrome | Epidermolysis Bullosa Simplex, Localized | Mountain Sickness | Scleritis | Pseudohypoparathyroidism Type 1A | Spondylocarpotarsal Synostosis Syndrome | CDKL5 Deficiency Disorder | Congestive Heart Failure | Leprosy | Spinocerebellar Ataxia Type 7 | Schwartz-Jampel-Aberfeld Syndrome | Retinal Diseases | Acromicric Dysplasia | Gyrate Atrophy Of The Choroid And Retina | Myelomeningocele | Pseudohypoparathyroidism Type 2 | Atopy | Zellweger Syndrome | Ghosal Syndrome | Spinocerebellar Ataxia Type 12 | Heart Block | Arthritis, Gouty | Irritable Bowel Syndrome | Pyruvate Carboxylase Deficiency Disease | Overactive Bladder | Toxic Epidermal Necrolysis | Asthma | Syphilis | Nevus | Persistent Mullerian Duct Syndrome | Corticobasal Syndrome | Rett Syndrome | Familial Advanced Sleep Phase Syndrome | Hypertensive Retinopathy | Thyroid Hormone Resistance | Juvenile Xanthogranuloma | Lactose Intolerance | Crouzon Syndrome With Acanthosis Nigricans | Alstrom Syndrome | Pachyonychia Congenita | Dysfibrinogenemia | Pituitary Stalk Interruption Syndrome | Absence Epilepsy | Mitochondrial Encephalomyopathy | Alopecia Areata | Trichorhinophalangeal Syndrome | Polymyositis | Congenital Torticollis | Prolactinoma | Glomerulonephritis | Mucolipidosis Type II | Oligoasthenoteratozoospermia | Agammaglobulinemia | Retinopathy Of Prematurity | Granuloma Annulare | Mosaic Variegated Aneuploidy Syndrome 2 | Anovulation | Agnathia-Otocephaly Complex | Synovitis | Pulmonary Tuberculosis | Amyotrophic Lateral Sclerosis-parkinsonism-dementia Complex | Kabuki Syndrome | Hypokalemia | Cardiofaciocutaneous Syndrome | Angioimmunoblastic T-cell Lymphoma | Blood Protein Disorders | Chromosome 17q21.31 Deletion Syndrome | Myosin Storage Myopathy | Heavy Chain Disease | Bulimia Nervosa | Fragile X Syndrome | Nephropathy | Malnutrition | Glioblastoma Multiforme | Otitis Externa | Tangier Disease | Alpers Syndrome | Cervicitis | X-linked Creatine Transporter Deficiency | Familial Digital Arthropathy-brachydactyly | Early Infantile Epileptic Encephalopathy 1 | Empyema | Vogt-Koyanagi-Harada Syndrome | Multiple Sclerosis | Hemolytic Uremic Syndrome, Atypical | Olmsted Syndrome | Polycystic Kidney, Autosomal Recessive | Epidermolysis Bullosa Simplex With Mottled Pigmentation | Congenital Central Hypoventilation Syndrome | Acquired Partial Lipodystrophy | Fibromuscular Dysplasia | Optic Neuropathy, Anterior Ischemic | Loeys-Dietz Syndrome Type 4 | Mixed Connective Tissue Disease | Menetrier Disease | Hypercalciuria | Sarcoma, Ewing | B-cell Chronic Lymphocytic Leukemia | Ellis-Van Creveld Syndrome | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Progressive External Ophthalmoplegia | Milk Allergy | Amebiasis | Goldenhar Syndrome | Hyperphosphatasia With Intellectual Disability Syndrome 4 | Histiocytic Sarcoma | Seizures-scoliosis-macrocephaly Syndrome | Osteopetrosis | Aphasia | Epithelioid Hemangioma | Spinocerebellar Ataxia Type 42 | Portal Vein Thrombosis | Tyrosine Hydroxylase Deficiency | Cardiac Arrest | Vitamin D Deficiency | HIBCH Deficiency | Astrocytoma, Anaplastic | Hidradenitis Suppurativa | Osteopathia Striata With Cranial Sclerosis | Lymphopenia | Shock, Cardiogenic | Charcot-Marie-Tooth Disease, Type 6 | Craniometaphyseal Dysplasia | Erythromelalgia | Varices | Ophthalmia, Sympathetic | Hypothyroidism | Chondroma | Netherton Syndrome | Epilepsy, Generalized | Hereditary Elliptocytosis | Malignant Peripheral Nerve Sheath Tumor | Apraxia | Dystonia Musculorum Deformans | PASLI Disease | Venous Insufficiency | Acute Leukemia | Osmotic Demyelination Syndrome | Myasthenia | Mast Cell Leukemia | Thrombophlebitis | Cutaneous Mastocytosis | Left Ventricular Noncompaction | ICF Syndrome | Wolcott-Rallison Syndrome | Alazami Syndrome | Viral Meningitis | Generalized Epilepsy And Paroxysmal Dyskinesia | Idiopathic Pulmonary Fibrosis | Frontometaphyseal Dysplasia | Insulinoma | Leukoplakia | Hyperglycemia | Nephrocalcinosis | Periodic Limb Movement Disorder | Influenza | Primary Erythromelalgia