Chylomicron Retention Disease

About the Disease
Chylomicron Retention Disease, also known as anderson disease, is related to hypolipoproteinemia and hypobetalipoproteinemia, familial, 2, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Chylomicron Retention Disease is SAR1B (Secretion Associated Ras Related GTPase 1B), and among its related pathways/superpathways are Metabolism and Transport of inorganic cations/anions and amino acids/oligopeptides. The drugs Benzocaine and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include liver, heart and bone, and related phenotypes are hypocholesterolemia and diarrhea

Common Targets
SAR1B | PCSK9 | KCNJ2

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