Alopecia

About the Disease
Alopecia is related to alopecia universalis congenita and alopecia-mental retardation syndrome 1, and has symptoms including exanthema and pruritus. An important gene associated with Alopecia is SASH1 (SAM And SH3 Domain Containing 1), and among its related pathways/superpathways are Direct p53 effectors and Validated transcriptional targets of TAp63 isoforms. The drugs Cetirizine and Histamine have been mentioned in the context of this disorder. Affiliated tissues include Hair, and related phenotypes are no effect and no effect

Common Targets
SULT1A1 | AMP-activated protein kinase (AMPK) | SMO | ERCC1 | ADK | G29126 | Prostanoid Receptor (nonspecified subtype) | WNT6 | GPR35 | HSD17B2 | PREP | Tyrosine-Protein Kinases Src (nonspecified subtype) | SLC28A3 | G7099 | NR3C2 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | FKBP4 | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | ACE | Protein kinase C (nonspecified subtype) | THRB | MOCOS | FKBP1A | IL17RA | KCNK18 | SRD5A1 | ABCC5 | EPHX2 | Hedgehog Protein (nonspecified subtype) | AKR1C2 | IL-31 Receptor | Thyroid hormone receptor (nonspecified subtype) | G1950 | CYP17A1 | TPMT | LPAR1 | ESR2 | KCND3 | TYR | HER (erbB) (nonspecified subtype) | CDK5 | Estrogen receptor (nonspecified subtype) | DNA Topoisomerase II (nonspecified subtype) | Steroid 5-alpha-Reductase (nonspecified subtype) | AQP3 | KRT17 | HDAC7 | PGR | HTR1A | HDAC5 | FGF5 | HDAC1 | PEG3 | Transforming growth factor (nonspecified subtype) | SRD5A2 | ENG | VIP | CNR1 | NFATC2 | MTRR | NUDT15 | Neurotrophic Factor (nonspecified subtype) | SYTL1 | CCN2 | PTGS1 | DKK1 | TIRAP | PTCH1 | G9429 | G3605 | ADRB3 | G7124 | HPGD | SYK | TGFBR1 | IMPDH1 | AADACL2-AS1 | GSTT1 | PTPN1 | NTRK1 | GSK3B | Prolactin receptor (isoform 1) | XDH | CXXC5 | FKBP5 | SLC19A1 | ERCC2 | IL-6 receptor | KCNA5 | IMPDH2 | K(ATP) Channel (nonspecified subtype) | EBF1 | PTGER4 | Amyloid beta A4 precursor protein-binding family (APP-BP) (nonspecified subtype) | G367 | CDK1/Cyclin B | G5743 | Anandamide membrane transporter (AMT) | GNRHR | ACP3 | CTLA4 | STS | AKR1C3 | G5243 | HDAC4 | RBM28 | FAAH | VDR | PDE3B | STAT4 | ABCC8 | FLT3 | PLCG1 | TGFB2 | Integrin alphaLbeta2 (LFA-1) receptor | Transforming growth factor beta (nonspecified subtype) | MTHFR | EPHA2 | Heat shock protein 70 (nonspecified subtype) | RORB | PDE5A | ITPA | TLR9 | NMDA receptor | TYMS | PTH1R | GMPS | PTGER1 | TRPA1 | VHL | TACR1 | APP | IL31RA | CREBBP | Muscarinic Acetylcholine Receptor (mAChR) (nonspecified subtype) | GSTM1 | WNT10A | GSTP1 | Mitochondrial pyruvate carrier complex (MPC) | Proteasome Complex | CYP19A1 | HSD17B1 | SFRP1 | MIF | UGT1A1 | EPHX1 | NLRP3 Inflammasome | MIR4713 | IL1B | G3569 | JAK3 | alpha-Amylase (nonspecified subtype) | CDK1 | AHSG | RARG | ABCC4 | JAK1 | Potassium Channels (nonspecified subtype) | CTNNB1 | MAOB | SLC29A1 | G114548 | JAK2 | PTGER2 | Soluble guanylyl cyclase | DPYD | SHMT1 | RAB27A | PDE3A | HSD17B3 | Vasoactive intestinal polypeptide receptor (VIP-R) (nonspecified subtype) | RAB27B | Transforming growth factor (TGF)-beta receptor (nonspecified subtype) | MBTPS2 | KCNJ11 | Glutamate Receptor Ionotropic AMPA Receptor | EDNRA | CSNK1E | HDAC2 | Cyclin B (nonspecified subtype)

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