Tic Disorder

About the Disease
Chronic Tic Disorder, also known as chronic motor or vocal tic disorder, is related to transient tic disorder and obsessive-compulsive disorder, and has symptoms including symptoms and recurrent muscle twitches (symptom). An important gene associated with Chronic Tic Disorder is SLITRK1 (SLIT And NTRK Like Family Member 1), and among its related pathways/superpathways are Transmission across Chemical Synapses and Protein-protein interactions at synapses. The drugs Guanfacine and Ondansetron have been mentioned in the context of this disorder. Affiliated tissues include brain, globus pallidus and caudate nucleus, and related phenotypes are nervous system and growth/size/body region

Common Targets
MGLL | GABRG2 | HTR2A | NMDA receptor | FAAH | GABRB3 | DRD2 | GABRA6 | KCNA2 | SLC6A2 | HTR1A | SLC18A2

Note: If you'd like to get a target analysis report for Tic Disorder, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Tic Disorder at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Congenital Hemolytic Anemia | Multiple Sulfatase Deficiency | Congenital Lipoid Adrenal Hyperplasia | Primary Ovarian Insufficiency | Leukocyte Adhesion Deficiency Type 1 | Scapuloperoneal Myopathy, X-linked Dominant | Imerslund-Grasbeck Syndrome | Waardenburg Syndrome Type 4A | Crimean-Congo Hemorrhagic Fever | Paraganglioma | Creutzfeldt-Jakob Disease | Proopiomelanocortin Deficiency | Shwachman-Bodian-Diamond Syndrome | Epilepsy | Geleophysic Dysplasia | GAPO Syndrome | Crigler-Najjar Syndrome | Nestor-Guillermo Progeria Syndrome | Intestinal Tuberculosis | Mitochondrial Encephalomyopathy | Irritable Bowel Syndrome | Colitis, Collagenous | Pelizaeus-Merzbacher Disease | Transient Bullous Dermolysis Of The Newborn | Waardenburg Syndrome Type 1 | Endometrial Hyperplasia | Tangier Disease | Acute Myeloid Leukemia | Medium-chain Acyl-CoA Dehydrogenase Deficiency | Charcot-Marie-Tooth Disease, Type 2A | Ameloblastoma | Crouzon Syndrome With Acanthosis Nigricans | Meningitis | Thrombocythemia, Essential | Blastoma, Pleuropulmonary | Congenital Bile Acid Synthesis Defect | Very Long-chain Acyl-CoA Dehydrogenase Deficiency | Hypertensive Nephropathy | Primary Progressive Aphasia | Blue Rubber Bleb Nevus Syndrome | Prediabetes | Usher Syndrome Type II | Guillain-Barre Syndrome | Contact Dermatitis | Spinocerebellar Ataxia Type 23 | Sezary Syndrome | Chromosome 17q21.31 Deletion Syndrome | Cholestasis, Intrahepatic | Erysipelas | Hyperbilirubinemia | Cardiomyopathy, Dilated, 1L | Exocrine Pancreatic Insufficiency | Myasthenia Gravis | Lattice Corneal Dystrophy Type 1 | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Charcot-Marie-Tooth Disease Type 2D | Lennox-Gastaut Syndrome | Veno-occlusive Disease | Paraganglioma, Carotid Body | Kabuki Syndrome | Sorsby Fundus Dystrophy | Polymyositis | Neutrophilia | Central Core Disease | Erythema Multiforme | Vitamin D Deficiency | Hypertension, Renal | Bernard-Soulier Syndrome | Ganglioglioma | Porphyria, Acute Intermittent | Kaposi Sarcoma | Retinitis | Vaginitis | Primary Progressive Nonfluent Aphasia | Acute Motor Axonal Neuropathy | Rhabdomyosarcoma, Alveolar | Leri Pleonosteosis | Methemoglobinemia Type IV | Seborrheic Dermatitis | Adenocarcinoma | Immunoproliferative Disorders | Diabetes Insipidus | Aneurysm, Thoracic Aortic | Hereditary Pyropoikilocytosis | Encephalopathy, Ethylmalonic | Hypercalcemia | Pemphigus | Blepharitis | Metaphyseal Chondrodysplasia, Schmid Type | Enterocolitis, Necrotizing | 3-methylglutaconic Aciduria Type I | Menkes Disease | Leiomyoma | Retinopathy Of Prematurity | Achromatopsia | Glycogen Storage Disease Type 1a | Fetal And Neonatal Alloimmune Thrombocytopenia | Aldosterone Deficiency | Angelman Syndrome | Schwannomatosis | Progressive Familial Intrahepatic Cholestasis Type 2 | Stuttering | Phenylketonuria II | Oligospermia | Bacterial Meningitis | Crohn's Disease | Zygomycosis | Choriocarcinoma | Takotsubo Cardiomyopathy | Early Infantile Epileptic Encephalopathy 4 | Enhanced S-cone Syndrome | Mast Cell Leukemia | Smoldering Myeloma | Kearns-Sayre Syndrome | 3-methylcrotonyl-CoA Carboxylase Deficiency | Ectodermal Dysplasia | Olmsted Syndrome | Pulmonary Veno-occlusive Disease | Heart Block | Multiple Mitochondrial Dysfunctions Syndrome Type 1 | Pleural Tuberculosis | Hodgkin Lymphoma | Astrocytoma | Gynecomastia | Chronic Thromboembolic Pulmonary Hypertension | Fanconi Syndrome | Primary Carnitine Deficiency | Supravalvular Aortic Stenosis | Mitochondrial DNA Depletion Syndrome | Tardive Dyskinesia | Maple Syrup Urine Disease | Pseudoachondroplasia | Heimler Syndrome | Familial Hypobetalipoproteinemia | Tyrosinemia Type 1 | Rheumatoid Arthritis | Metachromatic Leukodystrophy | Autism Spectrum Disorders | FG Syndrome | Pycnodysostosis | Persistent Hyperplastic Primary Vitreous | MELAS Syndrome | Otosclerosis | Allergic Contact Dermatitis | Infertility | Meningeal Melanocytoma | Charcot-Marie-Tooth Disease Type 4D | Loeys-Dietz Syndrome Type 4 | Plasma Cell Leukemia | Hypohidrotic Ectodermal Dysplasia | Pemphigus Vulgaris | Obsessive-compulsive Disorder | Bulimia Nervosa | Osteogenesis Imperfecta | Dystrophy, Cone-rod | Congenital Adrenal Hyperplasia | Cystinuria | Glomerulonephritis | Lymphomatoid Granulomatosis | Wilson's Disease | Primary Familial Brain Calcification | Congenital Aniridia | Hereditary Coproporphyria | Craniofacial Dysostosis | Hemangioblastoma | Renal Hypomagnesemia 3 | Ileitis | Prostatitis | Japanese Encephalitis | Congenital Dyserythropoietic Anemia Type 4 | 6-pyruvoyl-tetrahydropterin Synthase Deficiency | Asphyxia Neonatorum | Budd-Chiari Syndrome | Congenital Disorders Of Glycosylation Type II | Familial Pheochromocytoma-paraganglioma | Lung Diseases | Pneumonia, Viral | Sclerosteosis 2 | Oculopharyngeal Muscular Dystrophy | Demyelinating Diseases | Autism | WAGR Syndrome | Cheilitis | Rickets | Greig Cephalopolysyndactyly Syndrome | Corneal Ulcer | Leiomyosarcoma | Cerebral Cavernous Malformations | T-cell Leukemia | Anterior Segment Dysgenesis | Hennekam Lymphangiectasia-lymphedema Syndrome | Diastrophic Dysplasia | Hereditary Multiple Exostoses | Sweet Syndrome | Stickler Syndrome | Iron Metabolism Disorders | Gliosarcoma | Acne Vulgaris | Congenital Hereditary Endothelial Dystrophy Type I | Colitis | Mucolipidosis Type II | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 1 | Pernicious Anemia | Lymphedema | Diabetes Mellitus, Transient Neonatal | Papillorenal Syndrome | Localized Scleroderma | Spinocerebellar Ataxia Type 27 | Epithelioid Hemangioma | Babesiosis | Familial Partial Lipodystrophy | Thyroid Dysgenesis | Adenylosuccinate Lyase Deficiency | KBG Syndrome | Spinocerebellar Ataxia Type 3 | Acute Anterior Uveitis | Long QT Syndrome Type 3 | Parapsoriasis | Larsen Syndrome | Pure Red Cell Aplasia | Low Tension Glaucoma | Antisocial Personality Disorder | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Primary Aldosteronism | DOCK8 Immunodeficiency Syndrome | Haim-Munk Syndrome | Anti-NMDA Receptor Encephalitis | Trigonocephaly | Rett Syndrome | Anuria | Benign Familial Neonatal Convulsions | Spinal Cord Diseases | Celiac Disease | Greenberg Dysplasia | 17-beta-hydroxysteroid Dehydrogenase X Deficiency | Congenital Dysfibrinogenemia | Hyperuricemia | Okihiro Syndrome | Leber Hereditary Optic Neuropathy | Alopecia Areata | Pancreatitis | Avellino Corneal Dystrophy | Kabuki Syndrome 2 | Spinal Muscular Atrophy Type 2 | Sensorineural Hearing Loss | Lymphoma, Mantle Cell | Hypothalamic Obesity | Wolff-Parkinson-White Syndrome | Mucolipidosis | Osteogenesis Imperfecta Type I | Arterial Tortuosity Syndrome | Richter's Syndrome | Combined Pituitary Hormone Deficiency | Anodontia | Pseudohypoaldosteronism | Pyruvate Dehydrogenase Deficiency | POEMS Syndrome | Schistosomiasis Mansoni | Autoimmune Interstitial Lung, Joint, And Kidney Disease | Partington Syndrome | Endophthalmitis | Skin Fragility-woolly Hair Syndrome | Yellow Fever | Familial Male-limited Precocious Puberty | Werner's Syndrome | Hereditary Hemorrhagic Telangiectasia | Senior-Loken Syndrome | Micropenis | Neurodermatitis | Ectrodactyly | Trichomegaly | Axenfeld-Rieger Syndrome | Intellectual Disability, Autosomal Dominant 5 | Basan Syndrome | Aldosteronism | Angioimmunoblastic T-cell Lymphoma | Agnathia-Otocephaly Complex | Hidradenitis | Cyst | Multiple Congenital Anomalies-hypotonia-seizures Syndrome 2 | Niemann-Pick Disease, Type B | Encephalocele | Common Cold | Low Phospholipid Associated Cholelithiasis | Cholecystitis | Glomerulonephritis, Membranoproliferative | Blepharoconjunctivitis | Hypogammaglobulinemia | Esophagitis | Cholestasis | Alzheimer Disease, Late Onset | Primary Erythromelalgia | Addison Disease | Glomerulonephritis, Membranous | Focal Cortical Dysplasia Type 2 | Arrhythmogenic Right Ventricular Cardiomyopathy | Tularemia | Chronic Myelomonocytic Leukemia | Esophageal Motility Disorders | Craniosynostosis | NDH Syndrome | Ichthyosis Bullosa Of Siemens | Cryopyrin-associated Periodic Syndromes | Prune Belly Syndrome | Coloboma | COACH Syndrome | Ophthalmia, Sympathetic | Macular Corneal Dystrophy | Sitosterolemia | Isovaleric Acidemia | Hemoglobinopathies | Panniculitis | Intestinal Obstruction | Intracerebral Hemorrhage | Peters-plus Syndrome | Retinitis Pigmentosa 3 | Spondyloarthritis | Aicardi-Goutieres Syndrome | Hyperandrogenemia | Pituitary Disorders | Congestive Heart Failure | Lymphangioleiomyomatosis | Lamellar Ichthyosis | Tendinitis | Trismus-pseudocamptodactyly Syndrome | Diabetes | Erectile Dysfunction | Extramammary Paget's Disease | Ichthyosis Hystrix, Curth-Macklin Type | Sponastrime Dysplasia | Nephroblastoma | Inflammatory Myopathy | Pseudohypoparathyroidism Type 2 | Hernia, Inguinal | Fanconi Anemia | Leber Congenital Amaurosis | Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive 2 | CHARGE Syndrome | Eccrine Porocarcinoma | Ligneous Conjunctivitis | Mesothelioma, Malignant | Cervical Dystonia | Nasodigitoacoustic Syndrome | Juvenile Xanthogranuloma | Pseudoexfoliation Syndrome | Cocaine-Related Disorders | Potocki-Shaffer Syndrome | Evans Syndrome | Ovarian Sex Cord-stromal Tumor | Chediak-Higashi Syndrome | Nephrotic Syndrome | Hemorrhoids | Vertebrobasilar Insufficiency | Persistent Fetal Circulation | Schnitzler Syndrome | Non-bullous Congenital Ichthyosiform Erythroderma | Epithelial-myoepithelial Carcinoma | Noonan Syndrome | Discoid Lupus Erythematosus | Brenner Tumor | Jalili Syndrome | Non-small Cell Lung Cancer | Autoimmune Autonomic Ganglionopathy | Leishmaniasis, Visceral | Optic Nerve Diseases | Analgesia | Leprosy | Meniere's Disease | Hypopigmentation | Glioblastoma Multiforme | Prader-Willi Syndrome | Holoprosencephaly | Epidermal Nevus Syndrome | Beare-Stevenson Syndrome | T-cell Prolymphocytic Leukemia | Headache | Micro Syndrome | Rift Valley Fever | Polyneuropathy | Proctitis | Primary Cutaneous Amyloidosis | Hypophosphatasia | Venous Insufficiency | Microphthalmia | Anencephaly | Infantile Nephropathic Cystinosis | Situs Inversus | Multiple System Atrophy | Anorchia | Glycogen Storage Disease Type 4 | Myelofibrosis | Protein C Deficiency | Sleep Disorder | Cutaneous T-cell Lymphoma | Charcot-Marie-Tooth Disease, Type 1A | Coma | Behcet's Disease | Gout | Neurodevelopmental Disorder With Central Hypotonia And Dysmorphic Facies | Cancer, Prostate