Disease

Congenital Hereditary Endothelial Dystrophy Type I

About the Disease
Congenital Hereditary Endothelial Dystrophy Type I, also known as autosomal dominant congenital hereditary endothelial dystrophy, is related to corneal dystrophy, posterior polymorphous, 1 and contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a. An important gene associated with Congenital Hereditary Endothelial Dystrophy Type I is OVOL2 (Ovo Like Zinc Finger 2). Affiliated tissues include endothelial and eye.

Common Targets
OVOL2

疾病靶点研报
Congenital Hereditary Endothelial Dystrophy Type I

Note: If you'd like to get a target analysis report for Congenital Hereditary Endothelial Dystrophy Type I, or if you are interested to learn how our AI-powered BDE-Chem can design therapeutic molecules to interact with the target(s) above against the disease of Congenital Hereditary Endothelial Dystrophy Type I at a cost 90% lower than traditional approaches, please feel free to contact us at BD@silexon.ai.

Other Diseases

Partington Syndrome | MIRAGE Syndrome | Neural Tube Defect | Harlequin Ichthyosis | Angioedema, Acquired | Spondylocarpotarsal Synostosis Syndrome | Bleeding Disorder Due To CalDAG-GEFI Deficiency | Angelman Syndrome | Renal Hypouricemia | Fanconi Anemia | Gangliosidosis, GM1 | Torticollis | Primary Hyperoxaluria Type 3 | Rheumatic Heart Disease | Oculodentodigital Dysplasia | Succinic Semialdehyde Dehydrogenase Deficiency | Otitis Externa | Acne Vulgaris | Usher Syndrome Type III | Neurofibromatosis | Craniofrontonasal Syndrome | Hepatic Steatosis | Multicystic Renal Dysplasia | Esophageal Adenocarcinoma | Osteoglophonic Dysplasia | GM2-gangliosidosis AB Variant | Crigler-Najjar Syndrome | Atherosclerosis | Nephrotic Syndrome Type 1 | Dementia | Thanatophoric Dysplasia | Dystonia Musculorum Deformans | DNA Ligase IV Deficiency | Presbycusis | Angiosarcoma | 3C Syndrome | Pleomorphic Xanthoastrocytoma | Familial Partial Lipodystrophy | Hypokalemic Periodic Paralysis | Ataxia-hypogonadism-choroidal Dystrophy Syndrome | Rhabdomyosarcoma | Primrose Syndrome | Kabuki Syndrome 2 | Optic Neuritis | Dyskeratosis Congenita | Depression | Portal Vein Thrombosis | Hereditary Xerocytosis | Pure Autonomic Failure | Asplenia | Achondrogenesis | Actinomycetoma | 3-hydroxy-3-methylglutaric Aciduria | Lymphopenia | Wolcott-Rallison Syndrome | Basan Syndrome | CHARGE Syndrome | Palmoplantar Keratoderma | Iron Deficiency Anemia | Oligodendroglioma | Constipation | Chordoma | Keratosis | Bernard-Soulier Syndrome | Hyperkalemic Periodic Paralysis | Dupuytren Disease | Autoimmune Hemolytic Anemia | Demyelinating Diseases | Thyroiditis | Hypotrichosis Simplex | Camurati-Engelmann Disease | Sarcoidosis, Pulmonary | Dysplastic Nevus | Trichothiodystrophy | Bicuspid Aortic Valve | Glaucoma, Congenital | Behavioral Variant Of Frontotemporal Dementia | Focal Segmental Glomerulosclerosis | Polymicrogyria | Frontotemporal Dementia With Amyotrophic Lateral Sclerosis | Thrombotic Microangiopathy | Raynaud Phenomenon | Hereditary Coproporphyria | Leukoplakia | Coffin-Lowry Syndrome | Sleep Apnea | Jacobsen Syndrome | Sorsby Fundus Dystrophy | Perivascular Epithelioid Cell Tumor | D-2-Hydroxyglutaric Aciduria | Hemochromatosis Type 2 | Pupil Disorders | Ornithine Transcarbamylase Deficiency | Generalized Epilepsy And Paroxysmal Dyskinesia | Beta-Propeller Protein-associated Neurodegeneration | Ectrodactyly | Gastritis, Atrophic | Hyperlipidemia | Pseudohypoaldosteronism | Pseudohypoparathyroidism Type 1A | Glycogen Storage Disease Type 0, Muscle | Aicardi-Goutieres Syndrome | Diverticulitis | Cyclic Vomiting Syndrome | Giant Cell Glioblastoma | Congenital Nephrotic Syndrome | Primary Aldosteronism | Zygomycosis | Desbuquois Syndrome | Polymyositis | Hyperbilirubinemia, Neonatal | Cervicitis | Cutaneous Lupus Erythematosus | Withdrawal Syndrome | Congenital Adrenal Hyperplasia 1 | Li-Fraumeni Syndrome | Hypertension, Renovascular | Leri Pleonosteosis | 3-methylglutaconic Aciduria Type IV | Leukoencephalopathy, Progressive Multifocal | Nemaline Myopathy 10 | Prurigo Nodularis | Paraganglioma, Carotid Body | Synpolydactyly | Peeling Skin Syndrome, Acral Type | Muscular Dystrophy | Polydactyly | Micro Syndrome | Cluster Headache | Nephropathy | Nail Disorder, Nonsyndromic Congenital | Aarskog-Scott Syndrome | Mitochondrial Cytopathy | Neuronal Ceroid Lipofuscinosis | Osmotic Demyelination Syndrome | Granular Corneal Dystrophy Type 1 | Ileitis | Autosomal Recessive Congenital Ichthyosis | Meier-Gorlin Syndrome | Benign Familial Neonatal Convulsions | Cancer, Brain | Hereditary Neuropathy With Liability To Pressure Palsies | Early Infantile Epileptic Encephalopathy | Menkes Disease | Persistent Mullerian Duct Syndrome | DICER1 Syndrome | Recurrent Respiratory Papillomatosis | Meesmann Corneal Dystrophy | Glioma | Microphthalmia, Syndromic 7 | Endocarditis | Temporal Lobe Epilepsy | Acute Kidney Injury | Hypotrichosis, Congenital, With Juvenile Macular Dystrophy | Lymphoma, Primary Cutaneous Anaplastic Large Cell | Choroideremia | Isobutyryl-CoA Dehydrogenase Deficiency | Cannabis Abuse | Focal Dermal Hypoplasia | Walker-Warburg Syndrome | C3 Glomerulopathy | Opisthorchiasis | Primary Ovarian Insufficiency | DiGeorge Syndrome | Hypertensive Retinopathy | Hereditary Mixed Polyposis Syndrome | Hemosiderosis | Stuve-Wiedemann Syndrome | Congenital Bile Acid Synthesis Defect | Leukocyte Adhesion Deficiency Type 1 | Hypertriglyceridemia | DRESS Syndrome | Stickler Syndrome | Eating Disorder | Arthritis, Gouty | Oculocutaneous Albinism Type 1 | Antisocial Personality Disorder | Microvillus Inclusion Disease | Meningioma | Triphalangeal Thumb-polysyndactyly Syndrome | Bulimia Nervosa | Chromosome 16p11.2 Deletion Syndrome | Focal Facial Dermal Dysplasia | Intermittent Explosive Disorder | Charcot-Marie-Tooth Disease Type 4D | Androgen Insensitivity | Neonatal Progeroid Syndrome | Progressive Familial Intrahepatic Cholestasis Type 1 | Schnitzler Syndrome | Nail-Patella Syndrome | Epidermolysis Bullosa Simplex | Retinal Coloboma | Glycogen Storage Disease Type 0 | Episodic Ataxia | Peripheral Neuropathy | Carey-Fineman-Ziter Syndrome | Wiskott-Aldrich Syndrome | Micropenis | Azoospermia | Anosmia, Congenital | Vitreoretinal Degeneration, Snowflake Type | Chronic Neutrophilic Leukemia | Roberts Syndrome | Milk Allergy | Hereditary Spastic Paraplegia | Esthesioneuroblastoma | Congenital Dyserythropoietic Anemia | 3-M Syndrome | Anencephaly | Aspartylglycosaminuria | Anodontia | Gastroschisis | Superficial Spreading Melanoma | Sarcoma, Endometrial Stromal | Essential Fructosuria | Choroiditis | Mastitis | Netherton Syndrome | Sponastrime Dysplasia | Epidermolysis Bullosa Simplex, Dowling-Meara Type | Fuchs Dystrophy | Ocular Hypertension | Cholangitis | Von Hippel-Lindau Disease | Cholecystitis | Fibrosarcoma | Intracranial Hypertension | Craniometaphyseal Dysplasia | Niemann-Pick Disease, Type B | Reflex Epilepsy | Cold-induced Sweating Syndrome | Carcinoma, Merkel Cell | Spinocerebellar Ataxia | Bainbridge-Ropers Syndrome | Ameloblastoma | Lymphoproliferative Disorders | Mumps | Genitopatellar Syndrome | Spinocerebellar Ataxia Type 42 | Sarcoma | Calcium Pyrophosphate Deposition Disease | Swine Influenza | Dentinogenesis Imperfecta | Oguchi Disease-2 | Achromatopsia | Sick Sinus Syndrome 1 | Angioimmunoblastic T-cell Lymphoma | Epidermolytic Ichthyosis, Annular | Amebiasis | Diffuse Intrinsic Pontine Glioma | Central Retinal Artery Occlusion | Non-Hodgkin Lymphoma | Idiopathic Pulmonary Fibrosis | Postpoliomyelitis Syndrome | Aneurysm, Abdominal Aortic | Omenn Syndrome | Progressive Familial Intrahepatic Cholestasis Type 3 | Cholera | Juvenile Myoclonic Epilepsy | Cushing Syndrome | Ameloblastic Carcinoma | Dyslexia | Pemphigus Foliaceus | Usher Syndrome | Autonomic Nervous System Disorders | Multiple Sulfatase Deficiency | Oculocutaneous Albinism | Intermittent Claudication | Lipid Storage Diseases | Intestinal Pseudo-obstruction | Epilepsy Of Infancy With Migrating Focal Seizures | Cystitis, Interstitial | Hepatitis A | Pure Red Cell Aplasia | Peutz-Jeghers Syndrome | 5-oxoprolinase Deficiency | Porphyria, Variegate | Myeloid Leukemia | Dyslipidemia | Spinocerebellar Ataxia Type 40 | Norrie Disease | Autosomal Recessive Spastic Paraplegia Type 35 | Hyperostosis | Pilomatrix Carcinoma | VACTERL Association | Thyrotoxic Periodic Paralysis | Syphilis | Renal Tubular Dysgenesis | Astrocytoma, Anaplastic | Thin Basement Membrane Disease | Paraganglioma | Epidermolysis Bullosa Simplex, Localized | Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | Gerodermia Osteodysplastica | Cancer, Bladder | Hypospadias | Galloway-Mowat Syndrome | IgA Nephropathy | Sclerosteosis | Trismus-pseudocamptodactyly Syndrome | Hereditary Spherocytosis | Behcet's Disease | Otitis Media | Myhre Syndrome | Lipoma | Encephalopathy | Budd-Chiari Syndrome | Gardner Syndrome | Feingold Syndrome | IgA Deficiency | Language Disorders | Cyst | Rotor Syndrome | Patent Foramen Ovale | Saul-Wilson Syndrome | Vogt-Koyanagi-Harada Syndrome | Pancreatitis, Chronic | Hyperekplexia | Synovitis | Rolandic Epilepsy | Trimethylaminuria | Hyperprolactinemia | Sulfite Oxidase Deficiency | Spinocerebellar Ataxia Type 6 | Gaze Palsy, Familial Horizontal, With Progressive Scoliosis, 2 | Malignant Fibrous Histiocytoma | Hemophilia | Hyperphenylalaninemia | Adrenoleukodystrophy, X-linked | Pneumonia, Bacterial | Glanzmann Thrombasthenia | Schnyder Crystalline Corneal Dystrophy | Woodhouse-Sakati Syndrome | Sarcoma, Alveolar Soft Part | Epidermodysplasia Verruciformis | Microcephaly, Seizures, And Developmental Delay | Blepharophimosis Syndrome | Pyloric Stenosis, Infantile Hypertrophic | Spinocerebellar Ataxia Type 23 | Contact Dermatitis | Corneal Dystrophy | Chondroma | Scleritis | Anti-glomerular Basement Membrane Disease | Acromesomelic Dysplasia | Granuloma Annulare | Pontocerebellar Hypoplasia Type 2 | Mycosis Fungoides | Bloom Syndrome | Polycystic Ovary Syndrome | Pseudohypoparathyroidism Type 1C | Pendred Syndrome | Bronchiolitis | Kernicterus | Pseudohermaphroditism | Mitochondrial DNA Depletion Syndrome 13 | Oligospermia | Cranial Nerve Disease | Wiedemann-Steiner Syndrome | Craniopharyngioma | Scapuloperoneal Myopathy, X-linked Dominant | Spondylo-megaepiphyseal-metaphyseal Dysplasia | Leishmaniasis, Cutaneous | Hyperthermia, Malignant | Endometritis | Osteochondroma | Ophthalmoplegia | Proctitis | Pleurisy | Glomerulonephritis | Coronary Restenosis | Autism | Liver Failure, Acute Infantile | Turner's Syndrome | Macular Degeneration | Macrophagic Myofasciitis | Charcot-Marie-Tooth Disease Axonal Type 2N | Scapuloperoneal Spinal Muscular Atrophy | Rett Syndrome | Hyperinsulinemia | Transient Bullous Dermolysis Of The Newborn | Warsaw Breakage Syndrome | Craniolenticulosutural Dysplasia | Hypoparathyroidism | Episodic Ataxia Type 1 | Congenital Stationary Night Blindness | Coronary Artery Disease | Alpers Syndrome | Lentigo | Wagner Disease | Aphasia | Hidradenitis | Heart Septal Defects | Diabetes Mellitus, Transient Neonatal | Giant Cell Arteritis | Lafora Disease | Microcephalic Osteodysplastic Primordial Dwarfism, Type I | Oculocutaneous Albinism Type 4 | Pigment Dispersion Syndrome | Toxoplasmosis