Agammaglobulinemia

About the Disease
Agammaglobulinemia, also known as hypogammaglobulinemia, is related to agammaglobulinemia 1, autosomal recessive and agammaglobulinemia 4, autosomal recessive. An important gene associated with Agammaglobulinemia is BTK (Bruton Tyrosine Kinase), and among its related pathways/superpathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. The drugs gamma-Globulins and Rho(D) Immune Globulin have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, bone and b cells, and related phenotypes are splenomegaly and abnormality of bone marrow cell morphology

Common Targets
TTC7A | SH2D1A | TCF3

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