Premenstrual Syndrome

About the Disease
Premenstrual Tension, also known as premenstrual syndrome, is related to neurotic disorder and endogenous depression, and has symptoms including pelvic pain, unspecified symptom associated with female genital organs and mittelschmerz. An important gene associated with Premenstrual Tension is GNRH1 (Gonadotropin Releasing Hormone 1), and among its related pathways/superpathways are Prader-Willi and Angelman syndrome and "Antipsychotics Pathway (Metabolic Side Effects), Pharmacodynamics". The drugs Estradiol and Polyestradiol phosphate have been mentioned in the context of this disorder. Affiliated tissues include skin, brain and liver.

Common Targets
AVPR1A | NR3C2 | Folate Receptor (nonspecified subtype) | SRD5A1 | SRD5A2 | HTR1A | SLC6A2 | PGR | Estrogen receptor (nonspecified subtype) | GABA(A) receptor | HSD11B1 | Voltage-Gated Sodium Channel Complex | GNRHR | Sodium channel (nonspecified subtype) | G196 | G367 | SLC6A4 | 5-Hydroxytryptamine Receptor 2 (5-HT2) (nonspecified subtype) | SLC5A1 | HTR2A | HTR2C

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