Spastic Paraplegia Type 7

About the Disease
Spastic Paraplegia 7, Autosomal Recessive, also known as spg7, is related to paraplegia and spasticity, and has symptoms including leg cramps, pain in lower limb and urgency of micturition. An important gene associated with Spastic Paraplegia 7, Autosomal Recessive is SPG7 (SPG7 Matrix AAA Peptidase Subunit, Paraplegin), and among its related pathways/superpathways is Mitochondrial calcium ion transport. The drugs Acetylcholine and Cholinergic Agents have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, eye and brain, and related phenotypes are spastic gait and nystagmus

Common Targets
SPG7

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