Disease

Atrioventricular Septal Defect

About the Disease
Atrioventricular Septal Defect, also known as atrioventricular canal defect, is related to congenital heart defects, multiple types, 4 and ventricular septal defect 1. An important gene associated with Atrioventricular Septal Defect is SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin, Subfamily A Like 1), and among its related pathways/superpathways are G-AlphaQ Signaling and Human Embryonic Stem Cell Pluripotency. The drugs Benzocaine and Tannic acid have been mentioned in the context of this disorder. Affiliated tissues include heart, lung and atrioventricular node, and related phenotypes are growth/size/body region and homeostasis/metabolism

Common Targets
COL18A1 | GATA4 | CRELD2 | GNB2 | G7422 | FOXP1 | RAF1 | NKX2-5 | GATA5 | PTPN11 | COL6A1 | GJA1 | NR2F2 | COL6A2 | FBLN2 | COL6A3 | FRZB | CRELD1

疾病靶点研报
Atrioventricular Septal Defect

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