Vitiligo

About the Disease
Vitiligo-Associated Multiple Autoimmune Disease Susceptibility 1, also known as vitiligo, is related to alopecia areata and vogt-koyanagi-harada disease, and has symptoms including exanthema and pruritus. An important gene associated with Vitiligo-Associated Multiple Autoimmune Disease Susceptibility 1 is NLRP1 (NLR Family Pyrin Domain Containing 1), and among its related pathways/superpathways are Regulation of expression of SLITs and ROBOs and NF-kappaB Signaling. The drugs Dinoprost tromethamine and Dinoprost have been mentioned in the context of this disorder. Affiliated tissues include skin, thyroid and t cells, and related phenotypes are vitiligo and no effect

Common Targets
MC1R | CXCR5 | CASP7 | BCL2L12 | DEF8 | CPVL | ERCC1 | IL1RN | IL-15 receptor | FADS2 | G7099 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | MIR4435-2HG | Melanin | TEF | IL2RA | ACE | Folate Receptor (nonspecified subtype) | PSMB9 | FKBP1A | IL1RAPL1 | NAT2 | TYK2 | LTA | NEK6 | IFNGR1 | HLA-B | COMT | TYR | NR1H3 | IL4R | IRF3 | UBE2E2 | OCLN | LPP | TG | PPP3R2 | HLA-DRB1 | HMGCR | TICAM1 | HLA-G | LINC02265 | RALY | PPP3CC | SMOC2 | FOXD3 | PPP3CA | RERE | CD86 | IL-2 receptor | ABCA1 | FOXP1 | REL | SOD2 | GPX1 | IRF4 | HLA-A | ARID5B | BCHE | IL15 | SYK | G999 | G7124 | GZMB | FLI1 | SYNGR2 | CBFA2T3 | CES1 | UBASH3A | TSLP | NR3C1 | NPY | TLR2 | BACH2 | TNFAIP3 | HERC2 | CXCR3 | CTLA4 | SPATA48 | TNFRSF11A | VDR | STAT4 | FASN | DDR1 | MYG1 | NOS3 | CD80 | IL2 | EPHA2 | HCG9 | MTHFR | G196 | FASLG | CRHR1 | TXNRD1 | beta-Hexosaminidase Complex | PTPN22 | PON1 | PPP4R3B | IFIH1 | RNASET2 | IFNG | PARP12 | GAA | NOS2 | C1QTNF6 | CXCL10 | FAS | FARP2 | NLRP1 | G7422 | PPP3CB | LINC02356 | CCR5 | G6PD | PSMB8 | IL21 | PPP3R1 | FYN | GSTP1 | DHFR | PPARGC1B | TAP1 | XPA | IL4 | IL1B | JAK3 | JAK1 | PTPRC | CYP27B1 | HLA-C | IL13 | JAK2 | SLC1A2 | Melanocortin receptor (nonspecified subtype) | FOXP3 | HLA-DQB1 | IL9R | Interleukin 23 complex (IL-23) | IL2RB | ZMIZ1 | PLCB3 | XBP1 | G5133 | CAT | PVT1 | XPC | DDC | RAB5C | Protein Phosphatase 2B

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